Clinical trials
Liposomal Bupivacaine clinical trials
Below are recruiting liposomal bupivacaine clinical trials, each written for real people, not researchers. We’re tracking 55 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07792044Enrolling by invitation
Pain relief after shoulder surgery
This study tests a numbing medicine injected near the shoulder to see if it gives better pain relief after arthroscopic shoulder surgery than the standard approach. It might help you recover with less pain and fewer side effects.
Jiaxing, ZhejiangAges 18 years+ - NCT07689162RecruitingPhase 2
Long-acting vs standard numbing for nose surgery pain
This study compares two types of numbing medicine used during open rhinoplasty (nose surgery) to see which one controls pain better after surgery. One is a long-acting version (liposomal bupivacaine) and the other is the standard numbing medicine (bupivacaine).
St Louis, MissouriAges 18 years+ - NCT07458256Recruiting
Liposomal bupivacaine for pain after laparoscopic surgery
This trial tests a long-acting painkiller injected during surgery to see if it reduces pain after keyhole (laparoscopic) procedures like gallbladder removal, hernia repair, or appendix removal. It may help you need fewer opioids and recover more comfortably.
Beijing, Beijing MunicipalityAges 18–64 - NCT07458282Recruiting
Testing a long-lasting numbing medicine for pain after laparoscopic surgery
This trial is testing if a special numbing medicine called liposomal bupivacaine, given as a nerve block during surgery, can help reduce pain after laparoscopic procedures like gallbladder removal or hernia repair. It might help you feel better with less need for strong painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT07509866Recruiting
Comparing pain relief options for knee replacement surgery
This trial tests two different numbing medicines for knee replacement surgery. It compares a long-acting numbing medicine (liposomal bupivacaine) with a standard one (ropivacaine) mixed with other drugs to see which provides better pain control. The goal is to find a way to reduce pain and improve recovery.
Wuhan, HubeiAges 18–80 - NCT07458295Recruiting
Liposomal bupivacaine for pain after gynecologic cancer surgery
This trial tests whether a long-acting numbing medication (liposomal bupivacaine) injected into the abdominal wall can reduce pain after laparoscopic surgery for gynecologic cancer. If effective, it may help patients recover with less discomfort and fewer painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT06942689RecruitingPhase 4
Finding the best dose of numbing medicine for knee surgery pain
This trial tests different amounts of a long-lasting numbing medicine (liposomal bupivacaine) injected near the nerve in your thigh to see which volume works best for controlling pain after knee surgery. If you qualify, you may receive better pain relief and need fewer opioids.
Nanjing, JiangsuAges 18–85 - NCT07512635RecruitingPhase 4
Nerve Block Pain Relief for Minimally Invasive Lung Surgery
This trial tests whether numbing medication injected around nerves in the chest can reduce pain and help patients recover faster after minimally invasive lung surgery. The goal is to improve how you feel after the procedure.
Sanming, FujianAges 18–65 - NCT06179004RecruitingPhase 3
Numbing medicine comparison for wrist surgery pain
This study compares two types of numbing medicine (bupivacaine and liposomal bupivacaine) given near the collarbone before wrist surgery to see which provides better pain relief afterward.
Chapel Hill, North CarolinaAges 18 years+ - NCT06471348Recruiting
Pain control after scoliosis surgery: comparing two numbing medicines
This study compares two types of numbing medicine used during scoliosis surgery to see which provides better pain relief after the operation. One is a long-acting version (liposomal bupivacaine) and the other is a standard short-acting mix (bupivacaine with epinephrine). If you are a teen having surgery for Adolescent Idiopathic Scoliosis, this trial may help find a way to reduce pain and possibly lessen the need for opioids afterward.
Boston, MassachusettsAges 10–17 - NCT06737341RecruitingPhase 4
Liposomal vs. Standard Bupivacaine for Pain after Keyhole Abdominal Surgery
This trial tests whether a long-acting numbing medicine (liposomal bupivacaine) works better than standard bupivacaine to control pain after keyhole surgery on the liver, bile ducts, or pancreas. It may help you experience less pain and need fewer painkillers after surgery.
Wuhan, HubeiAges 18–80 - NCT06740214RecruitingPhase 3
Different doses of liposomal bupivacaine for knee replacement pain
This trial tests different doses of a long-acting painkiller (liposomal bupivacaine) injected into a nerve block in the thigh to see which dose works best for pain after knee replacement surgery. It may help you have better pain control and recover faster.
Hong Kong, Hong KongAges 18–80 - NCT07432711Recruiting
Liposomal bupivacaine for pain after lung surgery
This trial tests if a long-acting numbing medicine called liposomal bupivacaine can reduce pain after video-assisted lung surgery. It aims to help patients feel better after the procedure with less need for other painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT07441902Recruiting
Numbing medicine for lung surgery pain relief
This trial tests whether a numbing medicine (liposomal bupivacaine) injected near the ribs can reduce pain after lung surgery. If you qualify, you may experience less pain and need fewer painkillers after your operation.
Beijing, Beijing MunicipalityAges 18–64 - NCT07442539Recruiting
Numbing medicine for pain after hemorrhoid surgery
This trial tests a long-acting numbing medicine called liposomal bupivacaine to see if it reduces pain after hemorrhoid surgery better than standard care. It may be an option for people who are otherwise healthy and scheduled for this surgery.
Beijing, Beijing MunicipalityAges 18–64 - NCT07577934Recruiting
Liposomal Bupivacaine for Pain Relief in Gallbladder Surgery
This trial tests a long-acting numbing medication (liposomal bupivacaine) injected around abdominal muscles during laparoscopic gallbladder removal to reduce pain after surgery. The goal is to see if it provides better pain control compared to standard approaches.
Tianjin, Tianjin MunicipalityAges 18–65 - NCT06995352Enrolling by invitationPhase 4
Better pain relief after ankle surgery
This trial compares two methods of pain management after ankle surgery: a one-time injection of long-lasting numbing medicine (liposomal bupivacaine) versus a continuous nerve block via a small tube (catheter) placed near the nerve. The goal is to find which approach provides better pain relief with fewer side effects.
La Jolla, CaliforniaAges 18 years+ - NCT06646172Recruiting
Long-acting pain medicine during heart surgery
This trial tests a long-acting numbing medicine (liposomal bupivacaine) compared to standard local anesthetic during heart surgery through the breastbone. It aims to provide better pain control with fewer side effects.
Wuhan, HubeiAges 18–90 - NCT07587203Enrolling by invitation
Numbing medication for shoulder surgery and breathing
This trial compares two types of numbing medications (liposomal bupivacaine and standard bupivacaine) given as a nerve block for shoulder surgery. Researchers want to see which one works better for pain relief and causes fewer problems with your breathing afterward.
Nanjing, JiangsuAges 18–80 - NCT06565910RecruitingPhase 4
Pain relief after hip surgery: long-acting vs standard numbing medicine
This study tests if a long-acting numbing medicine (bupivacaine liposome) combined with a standard numbing medicine works better for pain control after hip fracture surgery. It compares two different combinations to see which provides more effective pain relief.
Wuhan, HubeiAges 18–60 - NCT05964868Enrolling by invitationPhase 3
Liposome anesthesia to reduce pain after nose surgery
This Phase 3 study tests whether a special form of local numbing medicine (liposomal bupivacaine) helps reduce pain after septorhinoplasty (nose and septum surgery). You may be considered if you’re planning this surgery and can follow study instructions before and after.
Hershey, PennsylvaniaAges 18–99 - NCT07263295Recruiting
Diaphragm function after shoulder block with long-lasting numbing medication
This study checks how a nerve block for upper arm surgery affects the diaphragm, the muscle that helps you breathe. It uses a long-lasting numbing medicine to see if breathing is affected.
Hangzhou, ZhejiangAges 18 years+ - NCT06284434RecruitingPhase 3
EXPAREL for pain after cleft gum repair
This trial tests if a long-lasting numbing medicine (EXPAREL) can help control pain after surgery to repair the gum in children and adults with cleft lip or palate. It may mean less discomfort after the procedure.
Chicago, IllinoisAges 6 years+ - NCT06529432RecruitingPhase 2
Study of a long-acting painkiller for lung surgery recovery
This trial tests a long-acting pain medication (bupivacaine liposome injection) to control pain after lung surgery done through a small cut. It may help you feel more comfortable and reduce the need for other pain medicines.
Shanghai, Shanghai MunicipalityAges 18 years+
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Common questions
- Are there clinical trials for liposomal bupivacaine?
- Yes. Clin2 currently lists 55 recruiting liposomal bupivacaine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a liposomal bupivacaine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a liposomal bupivacaine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.