Clinical trials
Bupivacaine clinical trials
Below are recruiting bupivacaine clinical trials, each written for real people, not researchers. We’re tracking 210 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06995352Enrolling by invitationPhase 4
Better pain relief after ankle surgery
This trial compares two methods of pain management after ankle surgery: a one-time injection of long-lasting numbing medicine (liposomal bupivacaine) versus a continuous nerve block via a small tube (catheter) placed near the nerve. The goal is to find which approach provides better pain relief with fewer side effects.
La Jolla, CaliforniaAges 18 years+ - NCT06740214RecruitingPhase 3
Different doses of liposomal bupivacaine for knee replacement pain
This trial tests different doses of a long-acting painkiller (liposomal bupivacaine) injected into a nerve block in the thigh to see which dose works best for pain after knee replacement surgery. It may help you have better pain control and recover faster.
Hong Kong, Hong KongAges 18–80 - NCT07458256Recruiting
Liposomal bupivacaine for pain after laparoscopic surgery
This trial tests a long-acting painkiller injected during surgery to see if it reduces pain after keyhole (laparoscopic) procedures like gallbladder removal, hernia repair, or appendix removal. It may help you need fewer opioids and recover more comfortably.
Beijing, Beijing MunicipalityAges 18–64 - NCT07458282Recruiting
Testing a long-lasting numbing medicine for pain after laparoscopic surgery
This trial is testing if a special numbing medicine called liposomal bupivacaine, given as a nerve block during surgery, can help reduce pain after laparoscopic procedures like gallbladder removal or hernia repair. It might help you feel better with less need for strong painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT07458295Recruiting
Liposomal bupivacaine for pain after gynecologic cancer surgery
This trial tests whether a long-acting numbing medication (liposomal bupivacaine) injected into the abdominal wall can reduce pain after laparoscopic surgery for gynecologic cancer. If effective, it may help patients recover with less discomfort and fewer painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT06646172Recruiting
Long-acting pain medicine during heart surgery
This trial tests a long-acting numbing medicine (liposomal bupivacaine) compared to standard local anesthetic during heart surgery through the breastbone. It aims to provide better pain control with fewer side effects.
Wuhan, HubeiAges 18–90 - NCT06737341RecruitingPhase 4
Liposomal vs. Standard Bupivacaine for Pain after Keyhole Abdominal Surgery
This trial tests whether a long-acting numbing medicine (liposomal bupivacaine) works better than standard bupivacaine to control pain after keyhole surgery on the liver, bile ducts, or pancreas. It may help you experience less pain and need fewer painkillers after surgery.
Wuhan, HubeiAges 18–80 - NCT07432711Recruiting
Liposomal bupivacaine for pain after lung surgery
This trial tests if a long-acting numbing medicine called liposomal bupivacaine can reduce pain after video-assisted lung surgery. It aims to help patients feel better after the procedure with less need for other painkillers.
Beijing, Beijing MunicipalityAges 18–64 - NCT07441902Recruiting
Numbing medicine for lung surgery pain relief
This trial tests whether a numbing medicine (liposomal bupivacaine) injected near the ribs can reduce pain after lung surgery. If you qualify, you may experience less pain and need fewer painkillers after your operation.
Beijing, Beijing MunicipalityAges 18–64 - NCT07442539Recruiting
Numbing medicine for pain after hemorrhoid surgery
This trial tests a long-acting numbing medicine called liposomal bupivacaine to see if it reduces pain after hemorrhoid surgery better than standard care. It may be an option for people who are otherwise healthy and scheduled for this surgery.
Beijing, Beijing MunicipalityAges 18–64 - NCT07689162RecruitingPhase 2
Long-acting vs standard numbing for nose surgery pain
This study compares two types of numbing medicine used during open rhinoplasty (nose surgery) to see which one controls pain better after surgery. One is a long-acting version (liposomal bupivacaine) and the other is the standard numbing medicine (bupivacaine).
St Louis, MissouriAges 18 years+ - NCT07573969RecruitingPhase 3
Pain Relief Medicines Added to Spinal Injection for Back Surgery
This trial tests whether adding one of two different medicines (dexmedetomidine or ketamine) to a numbing injection in the lower spine improves pain relief after back surgery. You would receive the injection while asleep during surgery to help manage pain afterward.
CairoAges 21–60 - NCT06165991RecruitingPhase 4
Comparing two types of numbing medicine for lung surgery pain
This trial compares two forms of a numbing medicine (bupivacaine) injected near the spine to reduce pain after lung surgery. It aims to find which works better for controlling pain after a lobectomy (removal of a lung lobe).
Jinan, ShandongAges 18 years+ - NCT07587203Enrolling by invitation
Numbing medication for shoulder surgery and breathing
This trial compares two types of numbing medications (liposomal bupivacaine and standard bupivacaine) given as a nerve block for shoulder surgery. Researchers want to see which one works better for pain relief and causes fewer problems with your breathing afterward.
Nanjing, JiangsuAges 18–80 - NCT07512635RecruitingPhase 4
Nerve Block Pain Relief for Minimally Invasive Lung Surgery
This trial tests whether numbing medication injected around nerves in the chest can reduce pain and help patients recover faster after minimally invasive lung surgery. The goal is to improve how you feel after the procedure.
Sanming, FujianAges 18–65 - NCT07263295Recruiting
Diaphragm function after shoulder block with long-lasting numbing medication
This study checks how a nerve block for upper arm surgery affects the diaphragm, the muscle that helps you breathe. It uses a long-lasting numbing medicine to see if breathing is affected.
Hangzhou, ZhejiangAges 18 years+ - NCT06179004RecruitingPhase 3
Numbing medicine comparison for wrist surgery pain
This study compares two types of numbing medicine (bupivacaine and liposomal bupivacaine) given near the collarbone before wrist surgery to see which provides better pain relief afterward.
Chapel Hill, North CarolinaAges 18 years+ - NCT06471348Recruiting
Pain control after scoliosis surgery: comparing two numbing medicines
This study compares two types of numbing medicine used during scoliosis surgery to see which provides better pain relief after the operation. One is a long-acting version (liposomal bupivacaine) and the other is a standard short-acting mix (bupivacaine with epinephrine). If you are a teen having surgery for Adolescent Idiopathic Scoliosis, this trial may help find a way to reduce pain and possibly lessen the need for opioids afterward.
Boston, MassachusettsAges 10–17 - NCT06565910RecruitingPhase 4
Pain relief after hip surgery: long-acting vs standard numbing medicine
This study tests if a long-acting numbing medicine (bupivacaine liposome) combined with a standard numbing medicine works better for pain control after hip fracture surgery. It compares two different combinations to see which provides more effective pain relief.
Wuhan, HubeiAges 18–60 - NCT07049094RecruitingPhase 4
Scalp nerve block for pain after brain surgery
This trial tests if a long-lasting numbing medicine (bupivacaine liposomes) injected into scalp nerves can reduce pain after brain surgery. It may help you need less pain medicine and feel better after your operation.
Hangzhou, ZhejiangAges 18 years+ - NCT05851768Recruiting
Easing thoracotomy pain with two different drugs
This trial compares two drugs added to a standard numbing medicine to see which works better for pain relief after chest surgery (thoracotomy). It may help find a way to reduce pain more effectively.
CairoAges 18–65 - NCT07550348Recruiting
Pain Relief Comparison for Lower Leg Surgery Nerve Block
This study compares two common numbing medications used together versus one alone for nerve-blocking surgery on the lower leg. Researchers want to see which approach works better and lasts longer for pain relief after your procedure.
ErzurumAges 18–65 - NCT07140640RecruitingPhase 4
Lowering anesthetic dose for C-section safety
This trial tests if using 20% less of a standard numbing medicine (bupivacaine) during a C-section can reduce the chance of the spinal block going too high. This may lower risks and improve safety for mothers.
Aswān, Aswan GovernorateAges 18–45 - NCT07783386Recruiting
Comparing nerve block volumes for breast surgery pain
This study compares different volumes of a nerve block (SPSIP) for pain relief after breast surgery. It aims to see if one volume provides better pain control with fewer side effects.
Nilufer, BursaAges 18–75
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Common questions
- Are there clinical trials for bupivacaine?
- Yes. Clin2 currently lists 210 recruiting bupivacaine studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a bupivacaine trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a bupivacaine trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.