Clinical trials
Cancer Risk clinical trials
Below are recruiting cancer risk clinical trials, each written for real people, not researchers. We’re tracking 722 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07242352RecruitingPhase 3
Comparing elacestrant to standard hormone therapy for high-risk early breast cancer
This trial tests a new hormone therapy drug called elacestrant against standard hormone treatments for people with a specific type of early breast cancer (ER+/HER2-) that has a high chance of coming back. The goal is to see if elacestrant works better at keeping the cancer from returning.
Mannheim, Baden-WurttembergAges 18 years+ - NCT06087068RecruitingPhase 2
Thyroid hormone therapy after lobectomy for low-risk thyroid cancer
This trial is testing whether thyroid hormone replacement after surgery is safe for people with low-risk papillary thyroid cancer. It may help maintain normal hormone levels after part of the thyroid is removed.
Beijing, Beijing MunicipalityAges 1.5 years–70 years - NCT07019363RecruitingPhase 3
CDK4/6 inhibitor plus hormone therapy for high-risk breast cancer
This trial tests whether adding a CDK4/6 inhibitor (a type of targeted pill) to standard hormone therapy after surgery can lower the risk of breast cancer coming back in women with high-risk, hormone-receptor-positive, HER2-positive early breast cancer.
ShanghaiAges 18–70 - NCT07622914Recruiting
Dietary fiber and muscle health in head and neck cancer
This study tests whether eating more fiber can help prevent muscle loss in people newly diagnosed with head and neck cancer. Researchers will track your nutrition and muscle strength over time to see if dietary fiber makes a difference.
Oklahoma City, OklahomaAges 18 years+ - NCT06523374Recruiting
Studying quality of life and cancer risk in Barrett's esophagus
This study looks at how Barrett's esophagus affects your quality of life and fear of cancer. It uses new tests to better predict who might develop esophageal cancer, so you can get the right care sooner.
Edegem, AntwerpenAges 18 years+ - NCT07279077RecruitingPhase 2
Low-dose radiation with chemo and immunotherapy for high-risk colon cancer
This trial tests a combination of low-dose radiation, chemotherapy, and an immunotherapy drug (PD-1 inhibitor) for people with a specific type of high-risk colon cancer that has not spread. The goal is to see if this approach can shrink the tumor before surgery and improve outcomes.
Guangzhou, GuangdongAges 18–75 - NCT05694559Recruiting
Genetic risk screening and counseling for Black adults
This study connects Black adults to genetic counseling and genetic testing to learn whether they may have an inherited cancer risk. It uses a simple risk screening tool, including visits by phone or video, to guide next steps.
Houston, TexasAges 18 years+ - NCT07051044Recruiting
Cheek swab light test for lung cancer risk
This trial uses a simple cheek swab and a special light test to look for signs of lung cancer risk. It aims to help doctors decide who needs more testing, especially if you have symptoms or are currently being checked for lung cancer.
North ShieldsAges 18 years+ - NCT06523868Recruiting
Multi-cancer early detection test for military veterans
This trial is testing a blood test that looks for early signs of multiple types of cancer. It is designed for current or former military members who are at least 45 years old and have used VA healthcare. If the test finds something, you would need to be willing to travel to Boston for follow-up.
Boston, MassachusettsAges 45 years+ - NCT07168993Recruiting
Testing a new sputum test for lung cancer in high-risk adults
This study tests a new, non-invasive sputum test (FlowPath Lung) to see if it can accurately detect lung cancer in people at high risk who have a lung nodule. If you are between 50 and 80, have a smoking history, and have a lung nodule, this test may help decide if further steps are needed.
Palo Alto, CaliforniaAges 50–80 - NCT05775471RecruitingPhase 2
Check PD-1 plus enfortumab after kidney-urine-duct surgery
This Phase 2 study tests giving pembrolizumab (an immune therapy) and enfortumab vedotin (an antibody-drug medicine) before and after surgery to remove high-risk upper urinary tract cancer. The goal is to lower the chance the cancer comes back.
Los Angeles, CaliforniaAges 18 years+ - NCT06628570Recruiting
Screening methods for anal cancer in high-risk adults
This study is looking at ways to screen for anal cancer in people who are at higher risk, such as those with weakened immune systems or a history of abnormal cells in the lower genital tract. It aims to find better methods for early detection.
Miami, FloridaAges 30–80 - NCT04428671RecruitingPhase 1
Cemiplimab before and after surgery for high-risk skin cancer
This Phase 1 trial tests the drug cemiplimab given before and after surgery to reduce the chance that high-risk cutaneous squamous cell cancer comes back. You may be a candidate if your cancer is high-risk on pathology or imaging and is planned for surgical removal.
Atlanta, GeorgiaAges 18 years+ - NCT06335420Recruiting
Can carrot juice prevent colon polyps from coming back?
This study tests whether drinking carrot juice every day can lower the chance that large colon polyps or early colon cancers will come back. Researchers want to see if the nutrients in carrot juice help protect the lining of the colon.
OdenseAges 18 years+ - NCT07392320RecruitingPhase 2
Immunotherapy or chemo pills after chemoradiation for high-risk nasopharyngeal cancer
This trial compares two options—a type of immunotherapy or a chemotherapy pill (capecitabine)—as maintenance treatment after standard chemoradiation for high-risk nasopharyngeal cancer. It aims to see which helps prevent the cancer from coming back.
Guangzhou, GuangdongAges 18–70 - NCT07438080Recruiting
HPV self-screening vs. doctor screening for anal cancer risk
This trial compares two ways to screen for HPV, a virus linked to anal cancer. People living with HIV will either collect their own sample or have a doctor do it, then switch methods. The goal is to see which is more comfortable and accurate.
Saint-PaulAges 30–65 - NCT07230639RecruitingPhase 2
Shorter radiation with chemo and immunotherapy for high-risk colon cancer
This trial tests a shorter course of radiation combined with chemotherapy and an immunotherapy drug (PD-1 inhibitor) for people with a specific type of high-risk colon cancer that has not spread. The goal is to see if this approach can shrink the tumor before surgery and improve outcomes.
Guangzhou, GuangdongAges 18–75 - NCT04453826RecruitingPhase 3
Test PD-1 plus chemo-radiation for high-risk nasopharyngeal cancer
This Phase 3 trial tests whether adding a PD-1 immunotherapy (given with chemotherapy and radiation, and also after) can improve outcomes for people with high-risk nasopharyngeal cancer. It may help by strengthening the immune system’s attack on the cancer alongside standard treatment.
Guangzhou, GuangdongAges 18–70 - NCT04912739Recruiting
Targeted health conversations in primary care
This study offers targeted health dialogues with people receiving care in primary settings, to see how well these conversations can support health. You may be invited because of your age and where you receive healthcare in Skåne County.
Malmö, Skåne CountyAges 40–70 - NCT05384769Recruiting
Blood test for early lung cancer screening in high-risk people
This study checks whether a blood test (a liquid biopsy) can be used along with standard lung cancer screening to find lung cancer early in people at higher risk. It may help see if the blood test is practical and useful for screening—without needing symptoms.
Duarte, CaliforniaAges 50–80 - NCT06268405Recruiting
PET scan and blood test for high-risk breast screening
This study tests a new PET scan machine for the breast (positron emission mammography) along with a blood test called a liquid biopsy for women who need a biopsy after a high-risk breast screening. It may help find cancer more accurately and less invasively.
Toronto, OntarioAges 18 years+ - NCT06384222RecruitingPhase 2
MRI scan to monitor response to abiraterone before prostate surgery
This trial tests whether a special MRI scan can show how well the drug abiraterone works against high-risk prostate cancer before surgery. If you have high-risk prostate cancer that hasn't spread, you might be able to take abiraterone for a few months and then have a prostatectomy, with the MRI helping your doctor see the drug's effect.
San Francisco, CaliforniaAges 18 years+ - NCT06507917Recruiting
HPV self-screening vs doctor screening for anal cancer in HIV
This study compares self-sampling (doing your own swab) to a healthcare professional doing the swab for HPV, a virus that can lead to anal cancer. It is for people with HIV on Réunion Island.
Saint-DenisAges 30 years+ - NCT06725576Recruiting
Comparing microwave ablation vs. surgery for low-risk thyroid cancer
This study compares a less invasive procedure (microwave ablation) with traditional surgery for treating a small, low-risk papillary thyroid cancer. If you have a single, small tumor with certain low-risk gene changes, you might be able to avoid surgery and have a quicker recovery.
Guangzhou, GuangdongAges 18–70
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Common questions
- Are there clinical trials for cancer risk?
- Yes. Clin2 currently lists 722 recruiting cancer risk studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer risk trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer risk trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.