Clinical trials
Cancer Risk clinical trials
Below are recruiting cancer risk clinical trials, each written for real people, not researchers. We’re tracking 717 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05348876RecruitingPhase 4
Darolutamide plus standard hormone therapy for high-risk prostate cancer
This trial studies how safe darolutamide is and how well it works when added to standard hormone therapy for men with high-risk, non-metastatic prostate cancer that is no longer responding to hormone treatment. It may help slow prostate cancer growth and reduce prostate-specific antigen (PSA) rises in real-world care.
Vijayawada, Andhra PradeshAges 18 years+ - NCT07239245RecruitingPhase 2
TACE plus immunotherapy for high-risk liver cancer before surgery
This trial tests whether a combination of two therapies—targeted chemotherapy delivered directly to the liver (TACE) plus immunotherapy (atezolizumab) and a targeted drug (bevacizumab)—can keep liver cancer from coming back after surgery. It is for people whose tumors can be surgically removed but are at high risk of recurrence.
Beijing, Beijing MunicipalityAges 18–75 - NCT06711068Recruiting
Chemotherapy plus targeted therapy for HER2+ early breast cancer
This trial tests whether adding targeted therapy to chemotherapy after surgery can help prevent HER2-positive early breast cancer from coming back. It is for patients whose cancer has not spread to lymph nodes and who have certain tumor sizes and features.
Beijing, Beijing MunicipalityAges Any age - NCT05923684Recruiting
English prostate cancer visit feedback tool for shared decisions
This trial tests an English computer tool that gives feedback during prostate cancer treatment visits. It aims to help you and your clinician make more informed, shared decisions about next treatment steps.
Los Angeles, CaliforniaAges 18 years+ - NCT06957626Recruiting
Predicting polyp return after removal
This study aims to develop a tool using gut bacteria and metabolites to predict if high-risk colon polyps will come back after removal. If you are between 40 and 75 and have had certain types of colon polyps removed, you may be able to help us build better prediction methods.
BeijingAges 40–75 - NCT06722599Recruiting
Shorter chemo with targeted drugs for low-risk HER2 breast cancer
This trial tests whether a short course of chemo plus two targeted drugs (trastuzumab and pertuzumab) before surgery works well for people with early-stage, low-risk HER2-positive breast cancer. It may help reduce the need for stronger chemo later.
Beijing, Beijing MunicipalityAges Any age - NCT06313359Recruiting
Understanding fall risk in people with nerve pain from cancer treatment
This study looks at how nerve damage from cancer treatment affects fall risk and quality of life. By comparing people with nerve symptoms to those without, researchers hope to find ways to improve safety and daily living.
Dallas, TexasAges 18 years+ - NCT05919758Recruiting
Looking at surgery for high-risk appendix tumors in children
This trial studies outcomes after removing the right side of the colon (right-sided hemicolectomy) in children who had a high-risk neuroendocrine tumor of the appendix. It aims to understand whether this more extensive surgery is valuable compared with other approaches.
Amsterdam-ZuidoostAges Up to 17 years - NCT06682728RecruitingPhase 2
Treating high-risk bladder cancer after surgery
This trial tests a combination of two drugs (sacituzumab govitecan and nivolumab) given after surgery to prevent the return of muscle-invasive bladder cancer. It is for patients whose cancer has a high chance of coming back despite surgery.
Orange, CaliforniaAges 18 years+ - NCT06696794RecruitingPhase 3
Testing mitomycin before surgery for high-risk bladder cancer
This trial tests whether giving mitomycin directly into the bladder before surgery can help people with high-risk non-muscle-invasive bladder cancer. The goal is to see if this approach is safe and effective at preventing cancer from coming back.
Wuhan, HubeiAges 18–75 - NCT06947083RecruitingPhase 2
Elranatamab after cilta-cel for high-risk multiple myeloma
This trial tests a new drug, elranatamab, for people with multiple myeloma who recently received a CAR-T cell therapy (cilta-cel) but still have high-risk features. The goal is to see if elranatamab can help keep the cancer from coming back.
Tampa, FloridaAges 18 years+ - NCT00040352Recruiting
Understanding melanoma risk in families and individuals
This research study helps doctors understand why some people and families develop melanoma (a serious skin cancer), especially in unusual circumstances. Researchers will collect medical histories, examine skin, and may do genetic testing to identify risk factors that could help with earlier detection and prevention.
Bethesda, MarylandAges 4 weeks–99 years - NCT03260842Recruiting
Biobank study for people at high risk of pancreatic cancer
This study collects and stores samples (bio-specimens) from adults who have pancreas cysts and are at higher risk for pancreatic cancer. The goal is to help researchers improve early detection so future patients may be diagnosed sooner.
Stanford, CaliforniaAges 18 years+ - NCT06135896RecruitingPhase 2
Study of a medicine to prevent low white blood cells from chemo
This trial tests a medicine (tripegfilgrastim) that helps prevent a serious drop in white blood cells (severe neutropenia) caused by certain chemotherapy. It is for people with advanced pancreatic or bile duct cancer who are starting a new treatment.
Goyang-si, Gyeonggi-doAges 19 years+ - NCT07439991Recruiting
Study of blood clot risks after lung cancer surgery
This study looks at why some people develop blood clots after lung cancer surgery. By tracking your recovery for 30 days, researchers hope to find better ways to predict and prevent clots in the future.
Changchun, JilinAges 18 years+ - NCT07180901Recruiting
Optimizing care for head and neck cancer surgery patients
This trial uses a computer system to send reminders and tracking alerts to doctors and patients, aiming to improve care and outcomes after surgery for head and neck cancer. It may help you stay on track with your treatment plan.
Montreal, QuebecAges 18 years+ - NCT07562490RecruitingPhase 2
Blood Test to Guide Chemotherapy After Colorectal Cancer Surgery
This study tests whether a special blood test (looking for cancer DNA) can help doctors decide if you need chemotherapy after colorectal cancer surgery. The goal is to avoid unnecessary chemotherapy while making sure patients who need it get treated.
ShanghaiAges 18–80 - NCT06722612Recruiting
Chemo plus targeted therapy for high-risk HER2+ early breast cancer
This trial tests whether combining chemotherapy with targeted therapy works better for women with high-risk, HER2 positive early breast cancer that hasn't spread to lymph nodes. If you've had surgery and your tumor fits certain high-risk features, you may be eligible to join.
Beijing, Beijing MunicipalityAges Any age - NCT06841653Recruiting
AI model to predict risk and improve treatment for endometrial cancer
This trial is testing whether a computer model powered by artificial intelligence can better predict outcomes for people with endometrial cancer or related conditions. It uses patient data and tissue samples to see if the model can help doctors choose the best care.
RomeAges 18 years+ - NCT07187908RecruitingPhase 2
Study of Efbemalenograstim Alfa to prevent low white blood cell counts in cancer patients
This trial tests if a drug called Efbemalenograstim Alfa can help prevent a serious drop in white blood cells (febrile neutropenia) during chemotherapy. It is for patients with solid tumors who have a high or intermediate risk of this condition.
Zhengzhou, HenanAges 18–75 - NCT07294040Recruiting
Low blood pressure after anesthesia in older cancer surgery patients
This study looks at what causes low blood pressure after anesthesia starts in older patients with cancer who are having surgery. It may help doctors prevent complications.
Ankara, AnkaraAges 65 years+ - NCT05962541RecruitingPhase 4
Using bladder scans to plan repeat surgery for bladder cancer
This trial checks whether a bladder scan and score (VI-RADS from MRI) can help doctors choose the right way to do a second look surgery for non-muscle-invasive bladder cancer. The goal is to reduce the chance of needing extra (“secondary”) resections while still catching important disease early.
Rome, LazioAges 18 years+ - NCT06086132Recruiting
Preventing heart damage from cancer treatment
This trial tracks how cancer treatments affect the heart. It may help doctors find ways to prevent heart problems during your treatment.
BolognaAges 18 years+ - NCT04047641RecruitingPhase 1/Phase 2
Quizartinib with chemotherapy for new or returning leukemia
This trial tests a combination of anti-leukemia drugs (including quizartinib) together with chemotherapy for people with acute myeloid leukemia (AML), a rare mixed-type leukemia, or high-risk myelodysplastic syndrome (MDS). It may help by trying to better control cancer in people whose disease is newly diagnosed or has returned/not responded to prior treatment.
Houston, TexasAges 18 years+
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Common questions
- Are there clinical trials for cancer risk?
- Yes. Clin2 currently lists 717 recruiting cancer risk studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer risk trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer risk trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.