Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06436612RecruitingPhase 2
Study of radiation therapy for belly or pelvic sarcomas
This trial is testing a precise type of radiation therapy (called SBRT) for people with sarcoma in the belly or pelvic area. The goal is to see if this targeted radiation can help shrink or control the tumor before surgery, and it may be an option if you haven't had radiation to that area before.
Los Angeles, CaliforniaAges 12 years+ - NCT06423170RecruitingPhase 2
Camrelizumab plus chemo for unresectable gallbladder cancer
This trial tests a combination of the immunotherapy drug camrelizumab with two chemotherapy drugs (gemcitabine and oxaliplatin, known as GEMOX) for people with gallbladder cancer that cannot be surgically removed. It aims to see if this treatment can help shrink the tumor and improve outcomes.
Guangzhou, GuangdongAges 18–75 - NCT06470971RecruitingPhase 2
Siltuximab to prevent severe side effects during immunotherapy rechallenge
This trial tests if siltuximab can prevent severe immune-related side effects when patients restart immunotherapy (anti-PD-1/PD-L1) after previous severe side effects. It aims to make rechallenge safer for people with advanced cancer.
Columbus, OhioAges 18 years+ - NCT06450873RecruitingPhase 2
Turkey tail mushroom before breast cancer surgery
This trial tests whether taking a turkey tail mushroom supplement before breast cancer surgery can help the immune system fight the cancer. It is for post-menopausal women with a common type of breast cancer (ER-positive, HER2-negative) that is growing at a moderate or faster rate (Ki-67 score of 10% or more).
Scottsdale, ArizonaAges 18 years+ - NCT06466395RecruitingPhase 1
Hyper-CVAD plus venetoclax for relapsed pediatric leukemia
This trial tests a combination of chemotherapy drugs (hyper-CVAD) plus a targeted pill called venetoclax for children and young adults with a type of leukemia that has returned or not responded to treatment. The goal is to see if this combo can help control the leukemia.
Houston, TexasAges 2–21 - NCT06402864RecruitingPhase 3
Internal radiation for rectal preservation in intermediate rectal cancer
This study is testing whether a special internal radiation treatment (contact X-ray brachytherapy) can help people with intermediate-stage rectal cancer avoid surgery and keep their rectum intact. It is for patients who are also receiving mFolfirinox chemotherapy.
Avignon, FranceAges 18–99 - NCT06181929Recruiting
Early lung cancer detection in Korean women with family history
This study looks at a new way to find lung cancer early in Korean women who have never smoked but have a family history of lung cancer. You would get a special CT scan (low-dose CT) to check for early signs of cancer, which could help catch it sooner.
Seoul, SeoulAges 45–74 - NCT06179069RecruitingPhase 1
Study of ZL-1310 for small cell lung cancer
This trial tests a new drug called ZL-1310, alone or with other treatments, for people with small cell lung cancer that has spread (extensive-stage). It aims to see if ZL-1310 can help shrink tumors or slow the disease.
Duarte, CaliforniaAges 18 years+ - NCT06167109Recruiting
NBI and MRI to guide radiation planning for one-sided nose cancer
This trial tests whether combining a special scope (NBI) with MRI scans can help doctors better target radiation therapy for a specific type of nose/throat cancer that affects only one side. It aims to make treatment more precise and reduce side effects.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06258863Enrolling by invitation
Comparing incision types in breast reconstruction after mastectomy
This study compares different types of surgical cuts (incisions) used during breast reconstruction after mastectomy. It looks at which incision gives the best cosmetic result and causes the fewest problems. Researchers want to find out which technique is best for you.
Wuhan, Hongshan DistrictAges 18 years+ - NCT06280508RecruitingPhase 2
Perioperative chemo plus immunotherapy for bile duct cancer
This trial tests a combination of chemotherapy, immunotherapy (adebrelimab), and a targeted therapy (apatinib) before and after surgery for bile duct cancer that can be removed and has a high risk of coming back. It aims to see if this approach can lower the chance of recurrence.
Guangzhou, China/GuangdongAges 18 years+ - NCT06241846RecruitingPhase 2
Study of YL201 for advanced prostate cancer that has spread and stopped responding to hormone therapy
This trial tests a new drug, YL201, in men with advanced prostate cancer that has spread and is no longer controlled by standard hormone therapy. The goal is to see if YL201 can shrink tumors or slow the cancer's growth.
Hefei, AnhuiAges 18 years+ - NCT06241781RecruitingPhase 2
Immune cells from your tumor for cervical cancer
This trial tests a new treatment using your own immune cells (called tumor-infiltrating lymphocytes) that are grown in a lab and given back to you. It is for people with cervical cancer that has come back or spread and hasn't been stopped by other treatments.
Beijing, Beijing MunicipalityAges 18–70 - NCT06184464Recruiting
Shrinking the prostate before radiation for prostate cancer
This trial tests how well the hormone drug leuprorelin acetate shrinks the prostate before radiation therapy for men with prostate cancer. The goal is to make radiation safer and more effective.
Terrassa, BarcelonaAges 18–95 - NCT06276686RecruitingEarly Phase 1
Exercise With Chemoradiotherapy for Locally Advanced Rectal Cancer
This study tests whether adding regular exercise during your standard chemoradiotherapy can help the treatment work better for people with locally advanced rectal cancer. It is designed for patients who have already been offered this type of therapy before surgery.
Cottingham, East YorkshireAges 18 years+ - NCT06327685RecruitingPhase 1
Avapritinib and Decitabine for SM-AHN
This trial tests a combination of two drugs, avapritinib and decitabine, for people with systemic mastocytosis plus another blood cancer (SM-AHN). The goal is to see if the combination works better than either drug alone.
Phoenix, ArizonaAges 18 years+ - NCT06307535Recruiting
Meaning-centered therapy for cancer caregivers
This study tests a type of therapy that helps caregivers find meaning and cope with the stress of caring for someone with advanced cancer. It is done online, so you can join from home.
Miami, FloridaAges 18 years+ - NCT06313359Recruiting
Understanding fall risk in people with nerve pain from cancer treatment
This study looks at how nerve damage from cancer treatment affects fall risk and quality of life. By comparing people with nerve symptoms to those without, researchers hope to find ways to improve safety and daily living.
Dallas, TexasAges 18 years+ - NCT06301399RecruitingPhase 2
Rituximab with prior therapy for advanced liver cancer
This trial tests if adding rituximab to previous cancer treatments can help people with advanced hepatocellular carcinoma (a type of liver cancer) that has stopped responding or caused side effects. It aims to see if this combination is safe and effective.
Tianjin, Tianjin MunicipalityAges 17–79 - NCT06317324Recruiting
SBRT vs. surgery for lung cancer with lobe spread
This study compares two treatments—stereotactic body radiation (SBRT) and surgery—for people whose non-small cell lung cancer has spread into the tissue between the lobes of the lung. The goal is to see which treatment leads to better long‑term results for this specific type of cancer.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT07199764RecruitingPhase 2
Maintenance therapy using combination immunotherapy for pancreatic cancer
This trial tests a combination of immunotherapy drugs (targeting CD40 and other immune cells) as a maintenance treatment for people with advanced pancreatic cancer that has not grown or has shrunk after initial chemotherapy. The goal is to see if this approach can keep the cancer from progressing longer.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06317558Recruiting
Real-world study of immunotherapy before surgery for lung cancer
This study looks at how well immunotherapy given before surgery works for non-small cell lung cancer. It aims to help doctors understand real-world outcomes for patients who receive this treatment.
Beijing, Beijing MunicipalityAges 18–85 - NCT06163729RecruitingPhase 2
Testing camrelizumab plus chemo and radiation before/after surgery for stomach-esophagus cancer
This trial tests combining the immunotherapy drug camrelizumab with chemotherapy and radiation before and after surgery for a specific type of stomach-esophagus cancer. It aims to see if this approach helps shrink the tumor and improve outcomes.
Beijing, Beijing MunicipalityAges 18–80 - NCT06292715Recruiting
Spleen shrinking procedure for severe hypersplenism
This trial tests a procedure that uses heat or cold to shrink part of the spleen and block some of its blood supply, which may improve low blood counts caused by cirrhosis-related hypersplenism. It is for patients whose low white blood cells or platelets have not improved with medicine.
Tianjin, Tianjin MunicipalityAges 18–65
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,308 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.