Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04099134Recruiting
Registry study for pancreatic ductal cancer before treatment
This is a “registry” study that collects health information from adults with pancreatic ductal adenocarcinoma before starting treatment. It may help researchers better understand the disease and how patients are managed in real life.
UlmAges 18 years+ - NCT04100174RecruitingPhase 2
HDR radiation boost for prostate cancer during standard treatment
This study tests adding a targeted “boost” of HDR (high-dose-rate) internal radiation to the prostate along with standard external beam radiation. It may help improve cancer control while keeping the treatment focused on the area seen on scans and biopsy.
Montreal, QuebecAges Any age - NCT04101656Recruiting
Shorter breast radiation for early breast cancer
This trial studies a radiation technique that treats only part of the breast using a faster schedule. It may help some people with early breast cancer after breast-conserving surgery by delivering effective treatment with less radiation to the rest of the breast.
SevilleAges 40 years+ - NCT04104607RecruitingPhase 1
Testing a PSMA-targeted immune drug for advanced prostate cancer
This Phase 1 study tests a new drug that aims to attach to PSMA on prostate cancer cells and activate T-cells (an immune cell type) to attack the cancer. It is for men with advanced prostate cancer that no longer responds to hormone therapy, especially after several prior treatments.
Tübingen, Baden-WurttembergAges 18 years+ - NCT04110756Recruiting
Program to help teens change health behaviors
This study tests a program designed to help teens make healthier choices. It’s for teens who are 15–17 and are currently drinking alcohol, who come to specific UCSF pediatric check-up visits.
San Francisco, CaliforniaAges 15–17 - NCT04111978RecruitingPhase 3
Maintenance hormone therapy after ovarian cancer responds
This Phase 3 trial tests whether ongoing treatment with an aromatase inhibitor (a hormone-blocking medicine) after initial chemotherapy can help keep epithelial ovarian/fallopian tube/peritoneal cancer from coming back. It is only for certain tumor types that are hormone-receptor positive (ER+).
GrazAges 18 years+ - NCT04114136RecruitingPhase 2
Study tests pembrolizumab or nivolumab plus a diabetes-like drug
This Phase 2 study tests whether adding a metabolic (diabetes-related) medicine to an immune therapy (pembrolizumab or nivolumab) can better control certain solid tumors. It may help people whose standard treatment would usually be pembrolizumab or nivolumab alone.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT04118660Recruiting
Thoracic specimen registry for adults with chest conditions
This study is a “specimen registry,” meaning it collects and stores samples from adults with chest (thoracic) diseases. It may help researchers better understand lung and chest conditions and improve future testing or treatments.
Rochester, MinnesotaAges 18 years+ - NCT04120935Recruiting
Observational study for adults with possible or confirmed bowel cancer
This study mainly watches and records health information from adults with colorectal cancer (or a strong suspicion of it). It collects past tumor tissue and other clinical details to better understand the disease and care.
Biella, BiellaAges 18 years+ - NCT04128072RecruitingPhase 2
Mogamulizumab plus skin radiation for cutaneous T-cell lymphoma
This trial studies mogamulizumab (an antibody medicine) plus total skin electron beam therapy (whole-skin radiation) to treat cutaneous T-cell lymphoma. It may help by improving skin symptoms and controlling the lymphoma after prior treatments.
CopenhagenAges 18 years+ - NCT04130971Recruiting
Testing tumor tissue to understand and predict colorectal cancer response
This study looks at tissue samples from people with colorectal cancer to better understand tumor features and how they may respond to treatment. If you have colorectal cancer, the trial may help researchers match future treatments more effectively.
GothenburgAges 18 years+ - NCT04135664RecruitingPhase 3
Compare surgery vs chemoradiation for early throat cancer
This study compares two ways to treat a type of esophagus cancer: surgical removal (esophagectomy) versus chemoradiation (chemo plus radiation). It is for people with early-stage findings where scans suggest no lymph node spread.
Nanchang, JiangxiAges 18–75 - NCT04136535RecruitingPhase 2
Treating resistant lung cancer with chemo plus or minus an added drug
This Phase 2 study tests whether adding an extra targeted medicine (anlotinib) to standard chemotherapy (pemetrexed and carboplatin) can better control osimertinib-resistant lung cancer with an EGFR mutation. It’s for people whose lung cancer has already progressed after osimertinib, and it aims to shrink tumors and slow the disease.
Shenzhen, shenzhenAges 18–75 - NCT04140487RecruitingPhase 1/Phase 2
Study drugs for certain FLT3-mutated blood cancers that have returned
This trial tests a combination of three medicines—azacitidine, venetoclax, and gilteritinib—in people with specific gene changes (FLT3 mutations) in leukemia and related bone marrow diseases that have come back or are hard to treat. The goal is to see if this drug combination can control the disease and improve outcomes.
Houston, TexasAges 18 years+ - NCT04165772RecruitingPhase 2
Dostarlimab for locally advanced mismatch-repair deficient solid tumors
This Phase 2 trial studies dostarlimab (an immune therapy that targets PD-1) given before surgery or other initial treatment. It aims to shrink certain locally advanced cancers that have mismatch repair deficiency, potentially making treatment easier and improving outcomes.
Hartford, ConnecticutAges 18 years+ - NCT04165798Recruiting
Pembrolizumab with or without chemotherapy for stage IV lung cancer
This trial tests whether pembrolizumab alone, or pembrolizumab plus chemotherapy, can treat stage IV non-small cell lung cancer. It may help shrink tumors and improve outcomes by boosting the immune system, with or without added chemotherapy.
Gilbert, ArizonaAges 18 years+ - NCT04170634Recruiting
CT scan study to assess bone strength in certain cancers
This study uses a CT scan to estimate how strong a cancer-affected bone area is, helping doctors evaluate fracture risk and bone management. It is aimed at adults with bone lesions from several common cancer types.
AngersAges 18 years+ - NCT04185935Recruiting
Genetic study of cancer in patients and their families
This study looks at DNA patterns in families where cancer may run in families, to better understand inherited (passed-down) cancer risk. You may be able to help even if you’re not sure whether your cancer is genetic—your family history and, if needed, medical records or tumor samples can be used.
Phoenix, ArizonaAges Any age - NCT04186585RecruitingPhase 1
Testing the safest dose for a prostate cancer drug
This early-phase trial (Phase 1) tests the safest dose of BP-C2 in people with prostate cancer who are on hormone treatment. It’s mainly designed to check safety and how the body handles the medicine, which could help future treatment options.
Skjetten, AkershusAges 18–80 - NCT04191551Recruiting
Study of stomach precancer conditions during endoscopy
This study looks at people with certain stomach symptoms or precancer risk factors when they get a camera test of the upper digestive tract (endoscopy). The goal is to learn how to better detect and evaluate stomach precancer conditions early, which may help guide treatment or follow-up.
Stanford, CaliforniaAges 35–84 - NCT04195633RecruitingPhase 2
Haploidentical donor stem cell transplant to treat blood cancers
This Phase 2 trial tests whether a specific stem cell transplant method (from a related “half-matched” donor) plus conditioning chemo and radiation can improve outcomes for several blood cancers. It may help people whose cancer is in remission but still considered high risk, or those who have had limited response after prior treatment.
Seattle, WashingtonAges 6 months+ - NCT04197297RecruitingPhase 2
Brain scan tests for biomarkers in people with brain metastases
This trial studies brain scan findings to see if specific imaging markers can help understand or predict outcomes in people with brain metastases. It may help researchers improve how brain metastases are evaluated before radiation treatment.
Toronto, OntarioAges 18 years+ - NCT04199026Recruiting
Tiny implanted device delivers drugs to sarcoma tumors
This trial tests an implantable device placed during planned surgery to deliver cancer medicines directly to sarcoma tumors and study how they affect the tumors. It may be an option if your sarcoma has come back or spread and surgery is part of standard care.
Houston, TexasAges 10 years+ - NCT04207437Recruiting
Daily handheld vibration therapy for chemotherapy nerve pain
This trial studies whether daily handheld vibration can lessen nerve damage symptoms in the hands after certain chemotherapy medicines. It may help reduce numbness, tingling, or pain from chemotherapy-related nerve problems.
Avon, IndianaAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,308 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.