Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,299 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05655494Recruiting
Helping underrepresented people find cancer clinical trials
This study tests an approach to help people from groups historically underrepresented in cancer trials learn about and connect to clinical trials. It may help you get easier, more personal ways to be contacted about research options.
Gainesville, FloridaAges 18–100 - NCT05655780Recruiting
Irinotecan care guided by tumor genes and gut bacteria
This study looks at whether a patient’s tumor genetic makeup and gut bacteria activity can predict how well irinotecan-based treatment works and what side effects they might have. It may help personalize treatment to improve survival and quality of life for people with metastatic or unresectable colon cancer.
Maastricht, LimburgAges 18 years+ - NCT05655949RecruitingPhase 2
Y-90 radiation plus immunotherapy and chemo for bile duct cancer
This trial studies whether combining Y-90 liver radiation with an immunotherapy drug (durvalumab) and chemo (gemcitabine and cisplatin) can better control locally advanced or metastatic intrahepatic cholangiocarcinoma (bile duct cancer in the liver). It may help shrink tumors and slow disease growth, depending on how well the treatment works for your cancer type and overall health.
Boston, MassachusettsAges 18 years+ - NCT05656807Recruiting
Weight management program for child care staff and families
This study tests a weight management program delivered through child care centers, involving teachers and parents. It aims to improve healthy habits for children ages 2–5 through changes in the child care setting.
Chapel Hill, North CarolinaAges 2 years+ - NCT05659732RecruitingPhase 1
Testing a new drug for advanced blood cancers
This early-phase study tests PEP07, a drug that blocks a cancer signal pathway (Checkpoint Kinase 1). It aims to see how well it works and how safely it can be given to people with certain advanced relapsed or refractory blood cancers.
Clayton, VictoriaAges 18 years+ - NCT05663203Recruiting
Web-based support program for colorectal cancer patients and caregivers
This trial tests a web-based coaching/support program done together by you and your main caregiver. It may help by addressing common emotional and brain-related symptoms during active chemotherapy.
Atlanta, GeorgiaAges 18 years+ - NCT05663502Recruiting
Donate blood and tissue samples for HIV-related cancer research
This study collects blood and tissue samples to help researchers learn more about cancers related to HIV/AIDS. You may be able to join if you’re 18+ and have HIV and a cancer diagnosis, or (if HIV-negative) a certain cancer that is closely linked to AIDS-related cancers.
La Jolla, CaliforniaAges 18 years+ - NCT05663242RecruitingPhase 4
Comparing anesthetics for outcomes after lung tumor surgery
This study looks at whether using different anesthesia drugs during planned lung tumor surgery affects recovery and longer-term outcomes. It also aims to understand why the anesthesia choice might make a difference.
Kaohsiung CityAges 20–80 - NCT05665361RecruitingPhase 1/Phase 2
Testing palbociclib plus sasanlimab for advanced kidney cancers
This study tests a combination of two medicines—palbociclib and sasanlimab—in people with advanced clear cell or papillary kidney cancer. It’s mainly designed to check safety (and early signs of how well the treatment may work) in these cancer types.
Bethesda, MarylandAges 18–100 - NCT05667948Recruiting
Testing targeted treatments for thymus cancer using tumor testing
This trial studies people with thymus (thymic) cancers that have been confirmed by tissue testing. It uses tumor “molecular” (biologic/genetic) test results to guide treatment options and see how well they work.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT05669846RecruitingPhase 2
FMT plus pembrolizumab for advanced lung cancer after prior treatment
This Phase 2 trial studies whether adding fecal microbiome transplant (FMT) to pembrolizumab can help people with advanced, PD-L1–positive non-small cell lung cancer that has returned or progressed after anti–PD-1/PD-L1 therapy. You may be asked to give new tumor tissue and undergo gut procedures, because the study aims to change gut bacteria to boost the immune response.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05672108RecruitingPhase 2
Chemo delivered into lung tumors using a catheter
This trial studies a treatment that delivers chemotherapy directly to lung tumors by placing a catheter into lung blood vessels. It may help people with lung cancer or lung metastases that are growing despite standard treatment, or who cannot tolerate it.
Duarte, CaliforniaAges 18 years+ - NCT05673928RecruitingPhase 2
Tucatinib and T-DM1 for HER2-positive brain-metastasis tumors
This Phase 2 study tests tucatinib plus T-DM1 (ado-trastuzumab emtansine) in people with HER2-positive metastatic solid tumors that have spread to the brain. It aims to shrink brain and body tumors and help control cancer that is progressing in the brain.
Houston, TexasAges 18 years+ - NCT05674396RecruitingPhase 2
Short-course radiation to ease symptoms from head and neck cancer
This Phase 2 trial tests a specific, shorter type of focused radiation to help relieve symptoms from head and neck squamous cell carcinoma. It compares two radiation timing/planning approaches to see which better improves comfort and quality of life.
Houston, TexasAges 18 years+ - NCT05675930RecruitingPhase 2
Light therapy for mouth GVHD after a stem cell transplant
This Phase 2 study tests a special light treatment (photobiomodulation) to improve oral graft-versus-host disease (GVHD) after a stem cell transplant. It may help people whose mouth symptoms have not improved with at least one prior treatment.
Bethesda, MarylandAges 4 years+ - NCT05676450Recruiting
Test blood DNA to find lymphoma changes and leftover disease
This study checks a blood test that looks for small DNA fragments (“cell-free DNA”) to find cancer changes that could guide treatment in diffuse large B-cell lymphoma. It also looks for “minimal residual disease,” meaning tiny amounts of lymphoma that may remain after treatment, and whether this test works across community cancer centers in Texas.
Houston, TexasAges 18 years+ - NCT05679557Recruiting
Assessing frailty before bladder surgery to improve recovery
This trial tests whether a thorough “geriatric assessment” (a health check focused on older adults) can help you be better prepared for bladder removal surgery. It may guide supportive care before and around surgery to improve safety and recovery.
OdenseAges 65 years+ - NCT05679349Recruiting
Help your clinic improve lung cancer screening for smokers
This study helps primary care clinics reach people who have a long smoking history so they can get lung cancer screening at the right time. It may help you (and others) get reminders and outreach to make screening easier to schedule.
Philadelphia, PennsylvaniaAges 50–77 - NCT05679921RecruitingPhase 2
Pazopanib, with or without pembrolizumab, for metastatic soft-tissue cancer
This Phase 2 trial tests pazopanib alone or together with pembrolizumab to slow or shrink metastatic soft-tissue sarcoma after prior chemotherapy. It may help some people by strengthening the anti-cancer effect compared with pazopanib by itself.
SeoulAges 20–80 - NCT05681962Recruiting
Improving breathing support during flexible bronchoscopy
This trial studies how to give oxygen and breathing support during a flexible bronchoscopy (a camera test through the airways). It may help make the procedure safer and more comfortable by refining the way oxygen is managed during the test.
CatanzaroAges 18 years+ - NCT05682131RecruitingPhase 4
Study for children with certain relapsed leukemia
This trial looks at treatment for children whose leukemia has come back for the first time. It focuses on a specific type of leukemia and risk level to see whether the approach improves outcomes.
Guangzhou, GuangdongAges 1–14 - NCT05686434RecruitingPhase 2
Osimertinib after surgery for early-stage EGFR-mutated lung cancer
This trial tests osimertinib (a targeted pill) given after surgery to help prevent early-stage lung cancer from coming back. It’s for people with fully removed, high-risk stage I non-small cell lung cancer that has specific EGFR gene changes.
Tianjin, Tianjin MunicipalityAges 18 years+ - NCT05686798RecruitingPhase 1
Gene therapy plus radiation for recurring brain tumor
This early-phase study tests a “suicide gene” therapy delivered by a virus along with radiation for adults whose high-grade brain tumor has come back or grown again. The goal is to see if the treatment is safe and can help control the tumor.
Detroit, MichiganAges 18 years+ - NCT05687084Recruiting
Uterine manipulator vs no manipulator in endometrial cancer surgery
This trial compares using a surgical “uterine manipulator” device versus not using it during endometrial cancer surgery. It may help clarify which approach is safer and works better during planned hysterectomy.
Cuneo, ItalyAges 18–100
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,299 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.