Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,052 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06207799RecruitingPhase 2
Drug combo before and after transplant for high-risk myeloma
This trial tests a two-step approach for people with newly diagnosed, high-risk multiple myeloma who are eligible for a stem cell transplant. You'll get a drug called elranatamab before transplant to 'purge' the cancer, and then after transplant, you'll get maintenance therapy guided by how well your cancer is controlled. The goal is to see if this reduces the chance of the cancer coming back.
Houston, TexasAges 18–75 - NCT06207812Recruiting
Skin Condition in Youth: Long-Term Study
This study looks at the long-term health of people who were diagnosed with a rare skin lymphoma (mycosis fungoides) or a related skin condition (lymphomatoid papulosis) before age 20. Researchers want to learn how these conditions affect people over time.
Houston, TexasAges 18 years+ - NCT06213311RecruitingPhase 2
CAR T-cells plus antibody drug for relapsed large B-cell lymphoma
This trial tests two immune-based treatments—first a special type of immunotherapy (CAR T-cells, called axi-cel), then a targeted antibody drug (glofitamab)—for people with large B-cell lymphoma that did not fully respond to their first treatment or came back within a year. The goal is to see if this combination can help more people achieve lasting remission.
Houston, TexasAges 18 years+ - NCT06206707Recruiting
FMT for Diarrhea and Colitis After Immunotherapy
This trial tests whether a treatment called fecal microbiota transplant (FMT) — transferring healthy gut bacteria — can help relieve diarrhea and colitis caused by immunotherapy drugs. If you have melanoma or kidney cancer and are experiencing diarrhea after immunotherapy, this study may offer a new option.
Aarhus NAges 18 years+ - NCT06211413Enrolling by invitation
Tracking heart issues in CLL patients on BTK inhibitors
This study watches for high blood pressure and irregular heartbeats in people with CLL who are starting a type of targeted therapy called a BTK inhibitor (acalabrutinib or zanubrutinib). Researchers will use a smartwatch and blood pressure cuff to monitor your heart health at home.
Philadelphia, PennsylvaniaAges 22 years+ - NCT06210854RecruitingPhase 2
HPV16/18 Vaccine Trial for Cervical Lesions
This trial tests a new vaccine (pBI-11) given with a device that uses mild electric pulses to help the vaccine enter cells. It is for people who have HPV16 or 18 but no high-grade cervical changes.
Birmingham, AlabamaAges 18 years+ - NCT06221800Recruiting
Gut bacteria and lung cancer treatment side effects study
This study looks at how the bacteria in your gut (microbiome) might affect how well your lung cancer treatment works and what side effects you experience. The goal is to learn if certain gut bacteria can predict treatment response or side effects for people with advanced non-small cell lung cancer.
Orange, CaliforniaAges 18 years+ - NCT06228482RecruitingPhase 1
Targeted radioactive therapy for advanced lung cancer
This trial tests a new targeted radioactive drug that seeks out a specific marker on lung cancer cells. It first uses a low-dose imaging scan to see if the cancer cells have this marker, then gives a higher-dose treatment to destroy those cells.
Sacramento, CaliforniaAges 18 years+ - NCT06217783Recruiting
Comparing IV catheter lengths for hard-to-find veins in cancer patients
This trial compares two different lengths of IV catheters placed with ultrasound help for cancer patients in the emergency room who have hard-to-find veins. The goal is to see which catheter length works best and lasts longer during a hospital stay.
Houston, TexasAges 18 years+ - NCT06219083Recruiting
Nutrition and outcomes in common cancers
This study looks at how nutrition affects recovery and results in people getting chemotherapy or radiation for common cancers. It may help improve care by tracking what you eat and how your body responds.
Xi'an, ShaanxiAges 18 years+ - NCT06207305RecruitingPhase 1/Phase 2
Paclitaxel into the belly for appendix cancer
This trial tests a chemotherapy drug (paclitaxel) given directly into the belly for people whose appendix cancer has spread inside the belly and cannot be surgically removed. The goal is to see if this approach is safe and helps shrink tumors.
Houston, TexasAges 18 years+ - NCT06207032Recruiting
Cancer biobank registry study
This study collects blood samples and health information from people diagnosed with cancer to build a research database. It may help future patients by enabling better understanding and treatment of cancer.
Birmingham, AlabamaAges 18–99 - NCT06216301RecruitingPhase 3
Electric fields with immunotherapy and chemo for advanced lung cancer
This trial tests adding a device that delivers electric fields (Tumor Treating Fields) to standard immunotherapy and chemotherapy for people with advanced non-small cell lung cancer that has not been treated before. It may help slow tumor growth.
Birmingham, AlabamaAges 18 years+ - NCT04644289RecruitingPhase 2
Olaparib plus durvalumab for early testing in ovarian cancer
This study tests whether olaparib and durvalumab given around the time of diagnosis can help people with advanced ovarian cancer. It also strongly focuses on collecting tumor and blood samples to better understand who may benefit.
Mannheim, Baden-WurttembergAges 18 years+ - NCT04962867RecruitingPhase 2
Targeting FGFR changes in advanced, hard-to-treat cancers
This Phase 2 study tests a treatment aimed at specific FGFR (a cancer-growth signal) changes found in your tumor. It may help people whose cancer has spread, cannot be removed, or has stopped responding to standard treatment.
Chuo-ku, Tokyo, JapanAges 20 years+ - NCT06195527Recruiting
Pembrolizumab blood level monitoring for NSCLC
This study checks how well pembrolizumab (Keytruda) works in people with non-small cell lung cancer (NSCLC) by measuring the drug levels in your blood. It aims to see if adjusting the dose based on these levels improves treatment and reduces side effects.
AngersAges 18 years+ - NCT06182774RecruitingPhase 3
Fixed vs ongoing treatment for older adults with new myeloma
This trial compares stopping treatment after a set number of cycles versus continuing it for people over 65 or those who cannot have a stem cell transplant. It tests whether a fixed treatment period works as well as long-term treatment for newly diagnosed multiple myeloma.
Edmonton, AlbertaAges 18 years+ - NCT06204614Enrolling by invitationEarly Phase 1
Drug screening for bladder cancer before surgery
This trial tests a tiny device placed into bladder tumors before surgery to see which drugs might work best for each patient, helping guide future treatment choices.
Boston, MassachusettsAges 18–120 - NCT06193356Recruiting
Can endoscopists learn to spot scar after polyp removal?
This study tests whether endoscopists can learn to see scarring and find any remaining tissue after polyp removal. It may help improve how doctors check for cancer coming back.
GhentAges 18 years+ - NCT06199492Recruiting
Smart optical probe to guide cancer needle biopsies
This study tests a new optical probe that takes special images during a needle biopsy to help guide doctors to collect better samples. It may help people with cancer in lymph nodes, liver, or lung who are already scheduled for an image-guided biopsy.
Houston, TexasAges 18 years+ - NCT06193083Recruiting
Deprescribing views of patients with advanced cancer
This study asks patients with advanced cancer about their thoughts on stopping medications that may no longer be needed or could be harmful. It aims to understand patient perspectives to improve care.
La Roche-sur-YonAges 18 years+ - NCT06183437RecruitingPhase 4
Can I stop heart meds after cancer therapy?
This trial tests whether it is safe to stop taking heart failure medications in people who developed heart weakness after cancer treatment but whose heart function has since recovered. It aims to see if stopping these drugs leads to any worsening of heart health.
Los Angeles, CaliforniaAges 18 years+ - NCT06194929RecruitingPhase 1/Phase 2
Drug combo for melanoma that spread to the brain
This trial tests a combination of two or three drugs (defactinib, avutometinib, with or without encorafenib) to shrink brain tumors that started from skin melanoma. It may be an option for people whose melanoma has a specific genetic change and who have already tried immunotherapy.
Iowa City, IowaAges 18 years+ - NCT06191133RecruitingPhase 1
Fenofibrate for cervical pre-cancer and cancer
This study tests whether a cholesterol-lowering drug called fenofibrate can help people with cervical pre-cancer or cancer. You take the drug before your scheduled surgery or chemoradiation, and doctors check if it reduces abnormal tissue or enhances treatment.
Cleveland, OhioAges 18 years+
Hear when a new Cancer (With or Without Metastasis) trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,052 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.