Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,042 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04945330Recruiting
Study for NTRK fusion cancers taking larotrectinib
This trial is for people with advanced or returning solid tumors that have specific gene changes called NTRK gene fusions. It looks at patients who are already being treated with larotrectinib as part of normal care, to understand this treatment in real life.
Multiple LocationsAges Any age - NCT04953910RecruitingPhase 1
Oral decitabine for cancers with liver problems
This Phase 1 trial studies how a pill form of decitabine/cedazuridine behaves in the body and how safe it is for people whose livers don’t work normally. It may help doctors better understand dosing and safety in patients with hepatic impairment.
Houston, TexasAges 18 years+ - NCT02129543Recruiting
Study immune recovery after stem cell or T-cell treatment
This study looks at how your immune system “rebuilds” after certain cell-based cancer treatments or stem cell transplants. It may help researchers better understand why immune recovery differs between people and how to improve protection against infections.
Miami, FloridaAges 18–75 - NCT04913064Recruiting
White button mushroom supplement for inflammation in high-risk breast cancer
This trial tests whether a white button mushroom powder supplement can lower inflammation in postmenopausal women who have a high risk of breast cancer. If it helps, it could improve early prevention strategies for people at higher risk.
Duarte, CaliforniaAges 21 years+ - NCT04934293Recruiting
Virtual reality support during proton radiation for children
This trial tests whether virtual reality (VR) can be used safely and comfortably for children receiving proton radiation. It aims to improve the experience of treatment by using a VR helmet during radiotherapy sessions.
NiceAges 7–18 - NCT04968834Recruiting
Collecting children’s and young adults’ blood and marrow for genetic testing
This study collects and stores blood and bone marrow samples from young people with certain blood cancers so doctors can do genetic (“genomic”) testing now and in the future. It may help improve understanding of the disease and support better matching of care for patients.
Hartford, ConnecticutAges Up to 30 years - NCT04988009Recruiting
Telemedicine care experience survey for brain tumor patients
This trial asks brain tumor patients and caregivers to share what they think about the quality of care they receive through telemedicine. Your feedback may help improve how neuro-oncology visits are done by video in the future.
Houston, TexasAges 18 years+ - NCT04991870RecruitingPhase 1
Early-stage immune cell therapy for recurrent grade 4 brain tumors
This Phase 1 trial tests a gene-edited immune cell treatment given into the brain to treat recurrent (returning) grade 4 glioblastoma or related tumors. It aims to find a safe dose and see whether the treatment can slow tumor growth.
Houston, TexasAges 12 years+ - NCT04949737Recruiting
Study stomach bacteria and stomach cancer in Martinique adults
This study looks at how common Helicobacter pylori (a common stomach germ) is in adults with stomach cancer in Martinique, and how it relates to stomach cancer. It mainly involves answering questionnaires and allowing study details to be collected to better understand risk and patterns.
Fort-de-FranceAges 18 years+ - NCT04934540Recruiting
Bladder tumor surgery approach registry study
This study is for adults who have a bladder tumor and are having a standard kind of surgery through the urethra. Researchers will collect information about this “en bloc resection” approach to better understand outcomes and care for people with bladder tumors.
Hong KongAges 18 years+ - NCT04986293Recruiting
CPAP or BiPAP to reduce motion during radiation
This study tests whether using a breathing machine (CPAP or BiPAP) can help keep you still during radiation treatment. This may improve how accurately radiation is delivered for certain cancers treated with curative intent.
Groningen, Provincie GroningenAges 18 years+ - NCT04982653RecruitingPhase 2
Stitch type study to prevent hernia after liver surgery
This trial compares two ways of closing the belly incision after open liver surgery to see which best lowers the chance of getting an incisional hernia (a bulge near the scar). It may help by guiding surgeons toward the closure method that prevents hernias better.
Houston, TexasAges 18 years+ - NCT04937309Recruiting
Vagus nerve stimulation for nausea from chemo
This trial tests a non-invasive device that stimulates a nerve in your ear to help prevent nausea caused by chemotherapy. It is for people with breast cancer who are about to start a specific type of chemo (anthracycline and cyclophosphamide).
BloisAges 18 years+ - NCT04987086Recruiting
68Ga PSMA PET-CT for kidney cancer spread
This study checks whether a special PET-CT scan using 68Ga PSMA can better find where renal cell carcinoma has spread. It may help doctors plan the right next steps by confirming suspected metastases on CT.
Lanzhou, GansuAges 18–90 - NCT04981821Recruiting
Mobile exercise coaching for older adults with blood cancers
This study tests whether a mobile (phone-based) exercise program can help older adults with myeloid blood cancers stay active and function better while they receive outpatient cancer treatment. You may be asked to follow an exercise plan and participate in assessments during the trial.
Rochester, New YorkAges 60 years+ - NCT04975152RecruitingPhase 1
Cemiplimab before surgery for Merkel cell and skin cancers
This early-phase study tests cemiplimab (an immune therapy that helps your immune system attack cancer) given before surgery. It aims to shrink tumors and improve outcomes for people with Merkel cell cancer or certain locally advanced skin squamous cell cancers (CSCC).
Tampa, FloridaAges 18 years+ - NCT04988074RecruitingPhase 2
Test cemiplimab for HPV-positive throat cancer using tumor biomarkers
This Phase 2 trial studies whether cemiplimab (with or without chemotherapy first) can improve treatment for HPV-positive oropharynx throat cancer. It also uses lab “biomarkers” to help guide which treatment you get next.
Baltimore, MarylandAges 18 years+ - NCT04933903RecruitingPhase 2
Neoadjuvant low-dose radiation plus immunotherapy before lung surgery
This trial tests whether giving low-dose focused radiation and two immunotherapy drugs before lung surgery can improve outcomes for people with operable, resectable non-small cell lung cancer. It aims to shrink or control the cancer before surgery and help reduce the chance it comes back.
Providence, Rhode IslandAges 18 years+ - NCT04994067Recruiting
Registering radiation given during breast-conserving surgery
This study records details about radiation delivered while your surgery is happening for certain early breast cancers or pre-cancers. It may help doctors better understand who benefits most from this “intra-operative” radiation approach.
The Bronx, New YorkAges 18 years+ - NCT04993859Recruiting
Testing how chemotherapy affects kids’ urinary markers
This study looks at urinary (bladder and urine) measurements in children who previously had cancer and were treated with certain chemotherapy drugs. It may help researchers understand how past chemotherapy can affect bladder function and related health markers over time.
Aurora, ColoradoAges 5–13 - NCT04942717Recruiting
Talking about health values with Spanish or English-speaking patients
This study tests an approach for discussing and sharing what patients value about their health, and adapting it for Latinx communities. It involves separate interviews with patients, families/caregivers, and oncology clinicians to improve how the intervention works and is understood.
New York, New YorkAges 21 years+ - NCT04954820RecruitingPhase 2
Second round Lutathera for intestinal NET after regrowth
This Phase 2 study looks at whether giving Lutathera again (a second round) can control an intestinal neuroendocrine tumor (NET) that came back or progressed after the first treatment. It mainly targets adults whose scan shows tumors still take up the right “target” signal and who previously benefited for at least 12 months.
AngersAges 18 years+ - NCT04928677RecruitingPhase 1
Codrituzumab for children and young adults with GPC3-positive solid tumors
This Phase 1 study tests codrituzumab, an antibody medicine, in children and young adults whose solid tumor has come back or did not respond to standard treatment. It’s designed to see how the treatment works and how safe it is, especially for tumors that test positive for GPC3.
Los Angeles, CaliforniaAges 1–21 - NCT04945317Enrolling by invitation
ROSE to improve lung cancer marker testing with a breathing scope
This trial studies a quick scan method (called ROSE) during bronchoscopy to help doctors get the right lung cancer tissue and test cancer markers more accurately. If you are being evaluated for non-small cell lung cancer, the study may improve how well and how fast your samples can be tested.
Chicago, IllinoisAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,042 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.