Clinical trials
Cancer (With or Without Metastasis) clinical trials
Below are recruiting cancer (with or without metastasis) clinical trials, each written for real people, not researchers. We’re tracking 13,278 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06028412Enrolling by invitation
Lobectomy vs. Sublobar Resection for Small NSCLC
This trial compares two types of lung surgery for early-stage non-small cell lung cancer. You may qualify if you have a small tumor (2 cm or less) with specific features on a CT scan. The goal is to see which surgery offers better outcomes.
Xi'an, ShannxiAges 18–75 - NCT05877456Enrolling by invitation
Checking a polyp-removal scoring tool for doctors
This study tests and confirms a scoring tool (GPAT) that helps describe how well doctors perform polyp removal during endoscopy. It may help standardize training and assessment, which can improve consistency in care.
Ghent, GentAges 18–100 - NCT05876390Enrolling by invitation
Regional anesthesia to reduce long-term breast surgery pain
This trial studies whether a pain-control technique called regional anesthesia during certain breast surgeries can lower chronic (long-lasting) pain after surgery. It may help improve comfort and quality of life for people at risk of ongoing pain after their breast operation.
Milan, LombardyAges 18 years+ - NCT05753046Enrolling by invitationPhase 4
Nerve-block during robotic prostate surgery to reduce pain
This trial studies whether a laparoscopic nerve block (called a TAP block) given during robotic prostate surgery can reduce postoperative pain. It compares comfort after surgery and looks for side effects or issues that could affect results.
Royal Oak, MichiganAges 18 years+ - NCT05746104Enrolling by invitationPhase 1
Testing a glowing dye to find nervous system tumor tissue
This early (Phase 1) study tests whether a glowing dye called indocyanine green helps surgeons better see nervous system tumor tissue during an operation, with the goal of lowering the chance of tumor coming back locally. It’s for adults whose tumor is expected to be removable and at risk for local recurrence.
Philadelphia, PennsylvaniaAges 18 years+ - NCT05699343Enrolling by invitation
Gum surgery for implant inflammation using bone filler and a membrane
This study tests a gum surgery approach to treat peri-implantitis (infection/inflammation around a dental implant). It compares using a bone substitute alone versus adding a dissolvable collagen membrane to see which helps the implant area heal better.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT05486520Enrolling by invitation
Low-field MRI test for breast cancer screening
This study tests a special MRI scanner that uses much weaker magnets to look at breast tissue for screening and possible follow-up. It may help find breast changes while aiming to reduce noise and discomfort compared with standard MRI.
Boston, MassachusettsAges 20–80 - NCT05415800Enrolling by invitation
Quality improvement pilot with healthy volunteers
This study is testing a quality-improvement approach in a group of normal, healthy volunteers. It may help improve how care or services are delivered, even though you may not have a specific illness in the study.
Lexington, KentuckyAges 18–99 - NCT05303532Enrolling by invitationPhase 3
Continue durvalumab after finishing a prior cancer study
This study lets people who already finished (or can no longer continue) an earlier AstraZeneca cancer treatment study keep receiving durvalumab. It tests whether continuing the same kind of treatment on a regular schedule can help keep your cancer under control.
Newport Beach, CaliforniaAges 18–99 - NCT05231993Enrolling by invitation
Treats HPV-positive atypical cervical cells found on screening
This study is for women whose cervical screening shows atypical glandular cells and who test positive for HPV types 16 or 18. It aims to decide the best way to triage and manage these findings so people get the right follow-up and treatment.
StockholmAges 23–64 - NCT05116137Enrolling by invitation
Exercise therapy to build muscle after glioblastoma
This trial studies whether a resistance (strength-building) exercise program can help survivors of glioblastoma keep or increase their muscle mass. If you are able to safely exercise, it may support recovery and overall strength after treatment.
Halifax, Nova ScotiaAges 18 years+ - NCT05102981Enrolling by invitation
Compare emergency versus planned stoma recovery and quality of life
This trial studies how having a stoma made in an emergency versus as a planned procedure may affect your day-to-day life and recovery. It may help doctors better understand which approach leads to better quality of life.
GothenburgAges 18 years+ - NCT05041166Enrolling by invitationPhase 1
MRI scan using a safe imaging molecule in healthy adults
This study uses a labeled nutrient-like molecule ([13C]pyruvate) to create clearer MRI images. It’s for healthy volunteers and helps researchers understand how well this imaging agent works.
New York, New YorkAges 18–80 - NCT05001009Enrolling by invitation
Goals of care conversation support for certain serious illnesses
This study helps primary care clinicians and their patients have structured “goals of care” conversations (about what matters most and care preferences). It may help you get clearer, earlier planning—especially if you have a serious illness and higher risk of hospitalization or death.
Palo Alto, CaliforniaAges 18 years+ - NCT04954625Enrolling by invitation
Blood patch treatment for leaking air after lung surgery
This study looks at whether an “autologous blood patch” (using your own blood) can help stop an air leak after certain lung operations. It’s designed for adults who still have an air leak on the morning of the third day after surgery.
Chicago, IllinoisAges 18 years+ - NCT04945317Enrolling by invitation
ROSE to improve lung cancer marker testing with a breathing scope
This trial studies a quick scan method (called ROSE) during bronchoscopy to help doctors get the right lung cancer tissue and test cancer markers more accurately. If you are being evaluated for non-small cell lung cancer, the study may improve how well and how fast your samples can be tested.
Chicago, IllinoisAges 18 years+ - NCT04879121RecruitingPhase 2
Larotrectinib for tumors with extra NTRK gene copies
This trial studies larotrectinib, a targeted medicine, in people with solid tumors that have extra copies (amplification) of the NTRK1, NTRK2, or NTRK3 gene. It’s for cancers that have already been treated with standard options or where standard options are unlikely to help.
Houston, TexasAges 16 years+ - NCT04762459Enrolling by invitationPhase 3
Almonertinib after lung tumor surgery, with or without chemo
This study tests whether almonertinib taken after complete surgery can improve outcomes for people with stage II–IIIA non-small cell lung cancer (NSCLC) that has certain EGFR gene changes. It also compares almonertinib plus chemotherapy versus almonertinib alone to see which approach is safer and works better.
Beijing, Beijing MunicipalityAges 18–130 - NCT04357574Enrolling by invitation
Testing a radiation treatment decision system during COVID-19 changes
This trial looks at whether a computer system can help guide high-intensity radiation treatment decisions when care has been disrupted during COVID-19. It may help improve how treatment is planned and adjusted during times when patients’ situations change.
Durham, North CarolinaAges 18 years+ - NCT04266093Enrolling by invitation
Gene therapy follow-up for adults previously treated at NCI
This study is a follow-up check for people who were previously enrolled in certain NCI gene therapy treatment studies. It helps the research team monitor long-term effects and outcomes after treatment.
Bethesda, MarylandAges 18–120 - NCT04202094Enrolling by invitation
Fertility options for young men after childhood cancer treatment
This study looks at fertility outcomes in young men who had cancer or blood disorders as children and then received high-risk treatment that can affect future fertility. It also compares people who did or did not store testicular tissue through a biopsy when they were younger.
BrusselsAges 18 years+ - NCT03907475RecruitingPhase 2
Durvalumab with chemotherapy for advanced solid tumors
This trial studies durvalumab (an immune therapy) combined with chemotherapy to treat advanced solid tumors that have grown despite prior standard treatment or have no proven standard option. It aims to improve control of the cancer and help people live longer.
Bethesda, MarylandAges 18 years+ - NCT03851458Enrolling by invitationPhase 2
Spanish coaching for healthier food choices for weight
This Phase 2 study tests a program (with food guidance, text messages, and check-ins) to help people eat more healthfully. It is designed for adults who are overweight or obese and can speak Spanish (with some separate tracks for different groups).
New York, New YorkAges 18 years+ - NCT03713229Enrolling by invitation
Seville study of people with HIV at risk for anal cancer
This study follows people living with HIV who may be at higher risk for anal cancer. It aims to better understand risk and outcomes, which could help guide future screening or prevention.
SevilleAges 18 years+
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Common questions
- Are there clinical trials for cancer (with or without metastasis)?
- Yes. Clin2 currently lists 13,278 recruiting cancer (with or without metastasis) studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cancer (with or without metastasis) trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cancer (with or without metastasis) trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Breast Cancer Early Stage Breast Cancer (Stage 1-3)
- Non Small Cell Lung Cancer
- Liver Metastasis Colon Cancer
- Gastric Cancer, Gastroesophageal Junction Cancer
- Lung Cancer Non-Small Cell Cancer (NSCLC)
- Colorectal Cancer Liver Metastasis
- Breast Cancer (Triple Negative Breast Cancer (TNBC))
- Leptomeningeal Metastasis of Breast Cancer
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.