Imaging mouth lesions during surgery to see them more clearly
Part of Cancer, Mouth & dental clinical trials.
This study uses a special dye and camera imaging while you have surgery or a biopsy to remove a mouth lesion. The goal is to better visualize the lesion during the operation, which may help doctors guide care more accurately.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be an adult (18 or older) with a mouth (oral) lesion scheduled for surgery or biopsy in the head/neck area
- You must be able to understand the study and agree to sign consent forms
- You must not have a known allergy to proflavine or acriflavine (the imaging dyes)
- You must not be pregnant or nursing (breastfeeding)
- You must not be in another research study that gives you an active medication during the time you are being imaged
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
Similar studies
Other trials that look related to this one.
This study tests a “precision optical” method to help guide an oral biopsy in people with abnormal or potentially cancerous mouth spots. It may help clinicians target the right area to sample, making diagnosis more accurate.
This study tests a new imaging technology (optical biopsy) that may help doctors find early signs of esophageal cancer during a routine endoscopy. It is for people who are already scheduled for a screening procedure with a special dye (Lugol's chromoendoscopy).
This study tests whether a special in-mouth imaging tool can capture clear images of oral cancer before surgery, compared with the final lab diagnosis from tissue (pathology). If the images match the pathology, it could help doctors better assess tumors using real-time imaging.
This trial tests noninvasive imaging methods to look at skin and mouth (mucosal) conditions. It may help doctors better see changes in these areas without taking tissue samples.
This study uses a special camera to look at solid tumors from inside the body during an operation. It tests whether “live” tumor imaging (using a medicine called fluorescein) can be safely performed in people with certain solid cancers.
This Phase 2 study tests a special camera and dye during surgery to help surgeons confirm they removed all cancer at the edge of the removed tissue. If it works, it may lower the chance of cancer being left behind after oral cavity or oropharynx squamous cell cancer surgery.
Hear when a new Oral Cavity Neoplasm trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.