Clinical trials
Children With Cancer clinical trials
Below are recruiting children with cancer clinical trials, each written for real people, not researchers. We’re tracking 147 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07444216Recruiting
A study on hope in teens and young adults with advanced cancer
This study explores hope in patients aged 12-25 with pediatric cancer that has returned, not responded to treatment, or has no cure. Participants take photos and share their stories to help doctors and families understand what hope means during early-phase clinical trials (phase 1 or 2).
Memphis, TennesseeAges 12 years+ - NCT04993859Recruiting
Testing how chemotherapy affects kids’ urinary markers
This study looks at urinary (bladder and urine) measurements in children who previously had cancer and were treated with certain chemotherapy drugs. It may help researchers understand how past chemotherapy can affect bladder function and related health markers over time.
Aurora, ColoradoAges 5–13 - NCT05918640RecruitingPhase 1/Phase 2
Lurbinectedin for cancers with specific EWS-related gene fusions
This early-phase study tests lurbinectedin, a chemotherapy medicine, in children and young adults whose solid tumors have a specific “FET fusion” gene change. It may help shrink tumors that have come back or did not respond to prior treatment, depending on the exact fusion type.
Los Angeles, CaliforniaAges 10 years+ - NCT07515430Enrolling by invitation
Gut Bacteria and Cancer Symptoms in Children With Leukemia
This study looks at how the bacteria living in your child's gut may affect cancer-related symptoms (like nausea, fatigue, or pain) during leukemia treatment. Researchers will collect stool samples and track symptoms to understand this connection better.
Guangzhou, GuangdongAges 5–18 - NCT01660984Recruiting
Natural history study for medullary thyroid cancer or MEN2
This study follows children and adults with medullary thyroid cancer (MTC) and/or MEN2 to better understand how the condition progresses over time. It may help doctors plan care in the future by collecting long-term health and lab information, not by giving a new treatment.
Bethesda, MarylandAges 4 months+ - NCT05999994RecruitingPhase 2
Testing new drugs for children and young adults with cancer
This trial tests several experimental drugs for children and young adults with cancer. It aims to find safe and effective treatments by matching participants to one of several drug studies based on their cancer type and health.
Birmingham, AlabamaAges 1–39 - NCT04475705RecruitingPhase 4
Propofol or sevoflurane for anesthesia in child tumor surgery
This trial compares two types of anesthesia medicine—propofol versus sevoflurane—during planned surgery to remove a solid tumor. It aims to find which option is safer and works better for children having curative tumor surgery.
Hong KongAges 6 months–18 years - NCT04477681Recruiting
Expanded access to cancer medicines for young people who need options
This trial helps children, teens, and young adults get an innovative cancer medicine when their disease has returned or hasn’t responded—and standard options are not available. It checks whether a “compassionate use” or off-label medicine plan can be carried out safely for the people who need it.
Villejuif, Val de MarneAges Up to 25 years - NCT05004116RecruitingPhase 1/Phase 2
Repotrectinib plus chemotherapy for relapsed solid tumors in youth
This early-phase study tests repotrectinib (a targeted anti-cancer pill) combined with chemotherapy in children and young adults whose solid tumors have come back or did not respond to standard treatment. The goal is to see how safe the treatment is and whether it can shrink tumors.
New York, New YorkAges 1–25 - NCT06761417RecruitingPhase 2
Liposomal mitoxantrone for children and young adults with relapsed solid tumors
This trial tests a new form of chemotherapy (liposomal mitoxantrone) for children, adolescents, and young adults whose solid tumors have come back or not responded to treatment. The goal is to see if this combination regimen can help shrink tumors.
BeijingAges 6–24 - NCT04644016RecruitingPhase 2
Cord blood transplant for children and young adults with blood cancers
This Phase 2 trial studies using a cord blood transplant after finding it is risky enough that standard treatment may not be sufficient. It may help certain children and young adults with specific leukemia, lymphoma, and some non-cancer blood/immune or inherited disorders who do not have a well-matched donor available in time.
New York, New YorkAges Up to 21 years - NCT07566377RecruitingPhase 2
Cord Blood Transplant for Children and Young Adults With Blood Cancer
This study tests whether using cord blood stem cells (collected from umbilical cords after birth) can help treat high-risk blood cancers in children and young adults when a matched donor is not quickly available. Cord blood transplants may help prevent cancer from coming back.
New York, New YorkAges Up to 26 years - NCT07727694Recruiting
Access to new cancer drugs for children and young adults
This trial helps children, teens, and young adults with cancer get early access to promising new drugs that are not yet fully approved for their age group. It collects information on how these drugs work in real-world use.
AntwerpAges birth–25 years - NCT03779854RecruitingPhase 2
Preventing graft-versus-host disease in kids after stem cell transplant
This trial tests whether removing certain immune cells (T cells) from the donor transplant can lower the risk of chronic graft-versus-host disease (long-term immune attack after transplant) in children and young adults with blood cancers. If you qualify, it may help improve transplant outcomes while tracking safety and side effects.
Los Angeles, CaliforniaAges 6 months–26 years - NCT04956133Recruiting
Physical activity program for kids during cancer treatment
This trial tests whether a structured physical activity program can help children and teens feel better and stay active during cancer treatment or shortly after. It involves the child and a parent/caregiver for safety during sessions.
Calgary, AlbertaAges 5–18 - NCT05748210Recruiting
App to help children’s cancer after-treatment symptoms
This study tests a smartphone/tablet app that helps children who have finished cancer treatment and their caregivers manage early symptoms that may come back after treatment. It may help families track symptoms and get supportive guidance during the early survivorship period.
Hong KongAges 9–16 - NCT06621810Recruiting
AI for melanoma detection in children and young adults
This study uses artificial intelligence to help detect melanoma (a type of skin cancer) and predict risk in children, teens, and young adults. Researchers want to see if AI can spot melanoma early and assess risk better.
TübingenAges Any age - NCT05975333Recruiting
Writing support for grieving parents of young cancer patients
This study offers a writing-focused intervention for parents who are grieving the loss of their child or young person who had a type of cancer (ChronCan). It aims to see whether guided writing can help with coping and emotional well-being during bereavement.
Memphis, TennesseeAges 15–25 - NCT07450872Recruiting
Gut health and symptoms in childhood cancer survivors
This study looks at how cancer survivors' symptoms (like pain, fatigue, or mood) are connected to the bacteria living in their gut. It aims to understand why some children have different symptom patterns after treatment, which could help doctors provide better care.
Hangzhou, ZhejiangAges 8–18 - NCT03910465Recruiting
Study for children and adults with chordoma
This trial studies people with chordoma (a rare bone/soft-tissue tumor) and collects information and samples to learn more about the disease. It may help by improving understanding of chordoma and supporting future research.
Bethesda, MarylandAges 2 years+ - NCT07381959Recruiting
Brain injury markers in children with brain tumors
This study looks at markers of brain injury in children with brain tumors who have or have not received radiation therapy, compared to healthy children. It aims to better understand how treatments affect the brain.
UppsalaAges Up to 17 years - NCT06612645RecruitingPhase 1
CAR T cell therapy for children with solid tumors that returned
This trial tests a new type of immune therapy called CAR T cells designed to find and attack a protein called B7-H3 on solid tumor cells. It's for children and young adults whose cancer came back or didn't respond to standard treatment.
Bangkok, PathumwanAges 1–25 - NCT06926751RecruitingPhase 2
Preventing low white blood cell counts in kids with solid tumors
This trial compares two drugs (Telpegfilgrastim and Filgrastim) to help prevent dangerously low white blood cell counts after chemotherapy in children and young adults with solid tumors. It's for patients who have already had this problem in a previous chemo round.
BeijingAges 6–24 - NCT05454618Recruiting
Deciding to join a pediatric cancer treatment trial
This study looks at the decision-making process for parents (or legal guardians) when their child is newly diagnosed with cancer and might consider enrolling in a treatment trial. It may help improve how families are informed and supported when making these choices.
Memphis, TennesseeAges Any age
Hear when a new Children With Cancer trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for children with cancer?
- Yes. Clin2 currently lists 147 recruiting children with cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children with cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children with cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.