Clinical trials
Children clinical trials
Below are recruiting children clinical trials, each written for real people, not researchers. We’re tracking 3,111 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04425434Recruiting
Treatment plan study for children with retinoblastoma
This trial looks at care recommendations for children with retinoblastoma (a childhood eye cancer). It may help standardize the best treatment approach for different patterns of tumor spread.
OuagadougouAges Up to 18 years - NCT04427462Recruiting
Study of energy balance and heart health in children
This study looks at how children’s “energy use” relates to heart and metabolism health. It may help doctors understand what healthy and unhealthy patterns look like in kids.
Little Rock, ArkansasAges 8–10 - NCT04439552Recruiting
MRI study during cornea cross-linking for keratoconus
This trial uses an MRI scan (and a close-up eye scan) to study what happens in the cornea during treatment for keratoconus. It may help doctors better understand how treatment works and who benefits most.
Boston, MassachusettsAges 8–35 - NCT04442516Recruiting
Testing kidney injury risk from cisplatin cancer treatment
This study looks at how cisplatin chemotherapy affects the kidneys. It may help doctors better predict and protect against kidney damage when patients start cisplatin.
London, OntarioAges 3 months+ - NCT04446442Recruiting
Brain stimulation study for children with autism symptoms
This study tests a noninvasive brain stimulation approach (through the scalp) to see if it can help children with autism spectrum disorder. Families may be asked about the child’s development, communication level, and medical history to make sure the treatment is safe.
Dallas, TexasAges 4–17 - NCT04455906Recruiting
Study why some people with eczema get more severe
This study looks at why disease tends to be more severe in some people with atopic dermatitis (eczema), especially those with a specific genetic change in the IL-4 receptor (IL-4Ra). The results may help explain what drives flare-ups and could guide better treatments in the future.
Boston, MassachusettsAges 6–65 - NCT04467671RecruitingPhase 2
Tested new blood vessel graft for a heart surgery
This trial studies whether a newer “tissue-engineered” blood vessel graft is safe and works well in children who need a specific heart surgery connection outside the heart. It may help by offering a new type of graft, but your team will screen for size and medical factors first.
Columbus, OhioAges Any age - NCT04475705RecruitingPhase 4
Propofol or sevoflurane for anesthesia in child tumor surgery
This trial compares two types of anesthesia medicine—propofol versus sevoflurane—during planned surgery to remove a solid tumor. It aims to find which option is safer and works better for children having curative tumor surgery.
Hong KongAges 6 months–18 years - NCT04477681Recruiting
Expanded access to cancer medicines for young people who need options
This trial helps children, teens, and young adults get an innovative cancer medicine when their disease has returned or hasn’t responded—and standard options are not available. It checks whether a “compassionate use” or off-label medicine plan can be carried out safely for the people who need it.
Villejuif, Val de MarneAges Up to 25 years - NCT04477928Recruiting
Checking type 1 diabetes risk using routine child care
This study estimates the chance of developing type 1 diabetes in children by using information gathered during regular well-child visits. It may help identify children who could benefit from earlier monitoring.
Bemidji, MinnesotaAges birth–17 years - NCT04477967Recruiting
Creating a liver transplant biobank for children
This trial sets up a long-term collection of medical information and samples from children who have had a liver transplant. It helps doctors study outcomes over time and improve care for future patients.
Chongqing, Chongqing MunicipalityAges 1 month–18 years - NCT04499066Recruiting
Mental health study during early pregnancy in Guangzhou
This study follows pregnant people in early pregnancy to better understand mental health during the perinatal (pregnancy and around delivery) period. It may help the clinic improve support for mental well-being before and after birth.
Guangzhou, GuangdongAges Any age - NCT04501718RecruitingPhase 2
Study of apatinib plus chemotherapy for recurrent childhood medulloblastoma
This trial tests whether adding apatinib to temozolomide and etoposide helps children whose medulloblastoma has come back. It aims to slow the tumor and improve outcomes after standard treatments.
BeijingAges 2–21 - NCT04510051RecruitingPhase 1
CAR T cell therapy for IL13Rα2 positive pediatric brain tumors
This Phase 1 study tests a type of immune therapy (CAR T cells) for children with brain tumors that come back or do not respond to standard treatment. The cells are given after chemotherapy that temporarily lowers the body’s immune system, which may help the CAR T cells work better.
Duarte, CaliforniaAges 4–25 - NCT04507997Recruiting
Study of the natural course of Angelman syndrome
This study follows people with Angelman syndrome to understand how their symptoms and development change over time. It may help researchers better describe the condition and support future treatments.
Los Angeles, CaliforniaAges Any age - NCT04528303Recruiting
Genetic testing comparison for long-lasting childhood diarrhea
This study compares two types of genetic tests—whole genome sequencing and whole exome sequencing—to find causes of long-lasting diarrhea in children. It may help doctors diagnose the reason for diarrhea faster, which can guide treatment.
Shanghai, Shanghai MunicipalityAges Up to 6 years - NCT04528082RecruitingPhase 3
Apremilast for children with frequent mouth ulcers from Behçet’s disease
This study tests apremilast to help reduce active, recurring mouth (oral) ulcers in children with Behçet’s disease. It may help if your child has had repeated mouth ulcers despite at least one non-biologic treatment.
BronAges 2–17 - NCT04529889Recruiting
Study of gestational diabetes during pregnancy and child outcomes
This study follows pregnant people with gestational diabetes to see how it affects mothers and babies over time. The team may use this information to better understand risks and care for both you and your child.
Guangzhou, GuangdongAges Any age - NCT04529967Recruiting
Screening kids for inherited high cholesterol
This study checks children ages 1 to 3 during routine care to see who may have familial hypercholesterolemia, a genetic condition that causes high cholesterol. Early identification can help families learn about next steps and prevention.
Hefei, AnhuiAges 1–3 - NCT04558736RecruitingPhase 2
Haploidentical transplant for severe aplastic anemia in children
This trial tests a “half-matched” stem cell transplant for children and teens with severe aplastic anemia when a fully matched donor isn’t available. It may help rebuild blood-making cells after prior treatments did not work well enough.
Memphis, TennesseeAges Up to 21 years - NCT04559425Recruiting
Registry study for immune-related serious slowed fetal heart rhythm
This study follows pregnancies where the baby has a serious immune-related heart rhythm problem (high-grade AV block). It collects information to better understand what happens during pregnancy and after delivery, especially when blood tests show anti-Ro/La antibodies.
Phoenix, ArizonaAges 16–50 - NCT04569162Recruiting
RCDP patient registry for children with related genetic conditions
This trial is a registry that collects medical and genetic information from people with rhizomelic chondrodysplasia punctata (RCDP) or closely related conditions. It helps researchers better understand the condition and plan future studies that could lead to better care.
Wilmington, DelawareAges Any age - NCT04571658Recruiting
NEPTUNE Match study linking you to possible kidney research trials
This study is an add-on process that uses information from the NEPTUNE kidney study to see whether you might be able to join other kidney research trials. It may help connect eligible people with appropriate new treatment studies when they become available.
Atlanta, GeorgiaAges 1–80 - NCT04577690RecruitingPhase 4
PECS pain study for children getting a chest device implanted
This trial tests a pain-control method (PECS) during surgery for children who are having a small chest device implanted. It may help reduce discomfort during and after the operation.
Toronto, OntarioAges 3–18
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Common questions
- Are there clinical trials for children?
- Yes. Clin2 currently lists 3,111 recruiting children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.