Clinical trials
Children clinical trials
Below are recruiting children clinical trials, each written for real people, not researchers. We’re tracking 3,111 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04230356RecruitingPhase 2
Viral immune T-cells for viral infections after stem cell transplant
This Phase 2 study tests donor-made immune T-cells that specifically target viruses to treat or prevent viral infections after a stem cell transplant. It may help your body control dangerous viruses like adenovirus, CMV, EBV, and BK virus, while checking safety with different timing of the treatment.
Cincinnati, OhioAges Any age - NCT04244721Recruiting
Parent training program for children with autism
This trial tests whether a parent-led program (with PACT) can improve autism-related symptoms in children. It focuses on giving parents structured support, and it compares outcomes after families complete the program.
BronAges 1.5 years–3 years - NCT04246944Recruiting
Induced membrane bone repair study in critical defects
This study looks at how a specific bone-repair technique (called induced membrane reconstruction) works in people with large “critical-sized” bone defects. It may help doctors understand the results and properties of this method in both children and adults.
AmiensAges 9 months–60 years - NCT04249830Recruiting
Donor stem cell transplant after donor cell targeting in youth
This trial studies a special donor stem cell transplant where the donor’s immune cells are reduced, aiming to lower harmful immune attacks after transplant. It may help children and young adults with certain high-risk blood cancers or rare bone marrow disorders.
Palo Alto, CaliforniaAges 1 month–60 years - NCT04254419RecruitingPhase 1
Natural killer cell injections in the brain tumor area
This early-phase trial tests injections of lab-grown immune cells directly into (or near) a brain tumor. It aims to see if the treatment is safe and can help control recurrent, progressive, or resistant CNS tumors.
Columbus, OhioAges 1–39 - NCT04289467RecruitingPhase 2
Fenfluramine for stubborn infantile spasms
This Phase 2 trial studies fenfluramine to treat infantile spasms that haven’t improved after standard medicines (ACTH and vigabatrin). If you/your child has ongoing seizures, the study may offer another treatment option and will monitor safety closely, especially heart-related side effects.
Los Angeles, CaliforniaAges 1–3 - NCT04293562RecruitingPhase 3
Testing targeted drugs plus chemo for newly diagnosed AML
This study compares standard chemotherapy to chemotherapy plus CPX-351 and/or gilteritinib in children and young adults newly diagnosed with AML. It aims to see whether adding these targeted treatments improves outcomes, especially for certain gene changes like FLT3.
Birmingham, AlabamaAges Up to 21 years - NCT04299828Recruiting
Study of inflammation activity during complex heart surgery
This study measures how active white blood cells and inflammation are during complex heart surgery using a heart-lung machine. It may help doctors better understand what triggers inflammation during surgery and how to improve care.
Boston, MassachusettsAges Any age - NCT04318678RecruitingPhase 1
CD123 CAR T-cell therapy for relapsed leukemia and related cancers
This early-phase study tests a lab-made immune therapy (CD123 CAR T cells) for children and young adults up to age 21 whose cancer has come back or didn’t respond to treatment. The goal is to see if these CAR T cells can find and attack cancer cells that carry a marker called CD123.
Memphis, TennesseeAges Up to 21 years - NCT04331353Recruiting
Asthma trial to reduce cockroach exposure at home
This study looks at whether reducing cockroaches in a child’s home can improve asthma control and reduce asthma flare-ups. It enrolls children who have ongoing (uncontrolled) asthma and will spend most nights in the study home.
New Orleans, LouisianaAges 5–17 - NCT04331639Recruiting
High-dose vitamin D for kids with IBD on biologic therapy
This trial studies whether giving a higher dose of vitamin D3 helps children and teens with inflammatory bowel disease (Crohn’s or ulcerative colitis) who have low vitamin D levels. Participants are already on biologic medicines and will be treated while monitoring blood (and safety) related to vitamin D.
Boston, MassachusettsAges 5–25 - NCT04338048Recruiting
Study for autosomal dominant polycystic kidney disease
This study enrolls people who have been diagnosed with autosomal dominant polycystic kidney disease (ADPKD), a genetic kidney condition that can cause kidney cysts. It aims to learn about this specific form of the disease so better care is possible for the right patients.
Washington D.C., District of ColumbiaAges Up to 18 years - NCT04358146Recruiting
Test a new formula to reduce infant spit-up
This study tests whether a new anti-regurgitation infant formula can reduce how often your baby spits up, and whether babies tolerate it well. It may help families who are feeding with formula and seeing frequent regurgitation (spit-up).
NamurAges 2 weeks–4 months - NCT04370899Recruiting
Early checkup for inherited high cholesterol in children
This study looks at children who may have inherited high cholesterol, especially when one parent is affected. It may help doctors detect the condition earlier and understand how it runs in families.
Reus, TarragonaAges 2–18 - NCT04370730Recruiting
Study brain and symptoms in youth with early psychosis
This study looks at how psychosis symptoms and development change over time in children and teens. It may help doctors better understand different patterns of illness and how to support young people with these disorders.
GentillyAges 7–20 - NCT04372485Recruiting
Text-message support to help teens finish STI antibiotics
This trial tests whether a mobile phone text-message program can help teens stick to their outpatient antibiotic treatment for common sexually transmitted infections (STIs). It may help improve cure rates by supporting correct medication timing and completion.
Washington D.C., District of ColumbiaAges 15–21 - NCT04372875Recruiting
Help for teens using health tech in the emergency room
This trial tests whether using a health information technology tool in the emergency department can improve sexual health care and reduce health disparities for teens. It focuses on gathering survey and screening information so care can better meet needs.
Washington D.C., District of ColumbiaAges 15–21 - NCT04375800RecruitingPhase 2
Doravirine for children with HIV infection and stable treatment
This Phase 2 study tests doravirine (a type of HIV medicine) in children with HIV who are about 4 weeks to under 12 years old and weigh under 45 kg. It aims to see whether this regimen can control the virus safely, and some children may continue into an extension if they benefit.
Aurora, ColoradoAges 4 weeks–11 years - NCT04380051Recruiting
Sensory touch therapy to help parents bond with very preterm babies
This study tests whether a gentle sensory “stimulation” approach can improve how parents and very preterm babies interact and support the baby’s social development. If you qualify, you and your baby would be asked to take part so researchers can see whether this early intervention helps bonding and social skills.
ReimsAges Up to 1 day - NCT04380740RecruitingPhase 2
Longer vs shorter abatacept doses to prevent graft-versus-host disease
This trial tests whether giving abatacept for a longer or shorter time can better prevent graft-versus-host disease (a common complication after a stem cell transplant). If you’re having a planned unrelated donor transplant, the results may help reduce the risk or severity of transplant-related immune problems.
Duarte, CaliforniaAges 2 years+ - NCT04390035Recruiting
Blood-flow training after ACL surgery for teens
This trial looks at whether a special exercise method that changes blood flow during physical therapy (called BFRT) can improve recovery after ACL reconstruction in teens. It may help strength and rehab progress, but you would need to meet several surgery and safety requirements and attend many PT visits.
Atlanta, GeorgiaAges 12–18 - NCT04395495Recruiting
RASopathy disorder study biobank for kids and families
This study collects and stores health samples and information from people with RASopathy conditions (like Noonan or Costello syndromes) and from family members who may not have the condition. It helps researchers understand these disorders and supports future studies that could lead to better care.
Cincinnati, OhioAges Any age - NCT04416178Recruiting
Survey and interviews for families affected by sickle cell disease
This study collects feedback through surveys, interviews, and focus groups from people affected by sickle cell disease. Your input helps the research team improve how genomic and gene-therapy information and needs are understood for patients and caregivers.
Memphis, TennesseeAges 13 years+ - NCT04425421Recruiting
Treatment plan for children with Burkitt lymphoma
This trial uses a recommended treatment approach for children who have Burkitt lymphoma, a specific type of blood cancer. It may help by guiding care when the full standard treatment schedule can’t be followed for every child.
OuagadougouAges Up to 18 years
Hear when a new Children trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for children?
- Yes. Clin2 currently lists 3,111 recruiting children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.