Clinical trials
Chronic Diseases in Children clinical trials
Below are recruiting chronic diseases in children clinical trials, each written for real people, not researchers. We’re tracking 157 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05457283RecruitingPhase 3
Finerenone safety study for children with kidney disease
This trial studies how safely finerenone works over 18 months in children and young adults with chronic kidney disease who also take an ACE inhibitor or ARB. It aims to better understand long-term side effects when used together with standard kidney blood-pressure medicines.
Palo Alto, CaliforniaAges 1–18 - NCT06430684RecruitingEarly Phase 1
SGLT2 inhibitor trial for children with kidney disease
This trial tests a medication called SGLT2 inhibitor (a type of diabetes drug that may also help protect the kidneys) in children with chronic kidney disease. It aims to see if the drug is safe and easy to use in children ages 2–18 with moderate to severe kidney problems.
Chicago, IllinoisAges 12–25 - NCT07768865Recruiting
Artery stiffness in young people with kidney disease
This study looks at how stiff the arteries are in children and young adults with chronic kidney disease (CKD) compared to healthy controls. The results may help doctors better understand heart risks and improve care for young people with kidney problems.
London, Greater LondonAges 10–25 - NCT06820593Recruiting
Asthma care with technology for kids and families
This study tests whether a sensor that tracks inhaler use can help children ages 4–17 with persistent or uncontrolled asthma. It aims to make managing asthma at home easier for caregivers.
Chicago, IllinoisAges 4 years+ - NCT07544524Recruiting
Plant-Based Diet for Kidney Disease in Asian Adults
This study tests whether eating mostly plants (with some animal products) can safely help people with moderate kidney disease. Researchers will compare this diet to a standard kidney-friendly diet and see how it affects kidney function and overall health.
SingaporeAges 21–79 - NCT07716488Recruiting
Screening for high cholesterol in children with chronic conditions
This study screens children and teens with certain chronic conditions (like heart defects or inflammatory bowel disease) for early signs of high cholesterol or other lipid problems. The goal is to find and manage these risks sooner.
JenaAges 6–18 - NCT03991169RecruitingPhase 4
Oral iron for children with chronic kidney disease
This trial studies whether taking iron by mouth can improve iron levels and anemia (low red blood cell counts) in children with chronic kidney disease. It may help reduce fatigue and support normal blood-making, by comparing different approaches for children who meet specific iron test results.
New York, New YorkAges 1–21 - NCT04741646RecruitingPhase 2
Ferric citrate for kids with chronic kidney disease
This Phase 2 study tests ferric citrate, a medicine that helps control phosphate and iron balance, in children with chronic kidney disease. It may help slow problems related to kidney disease by improving lab measures like phosphate levels.
Los Angeles, CaliforniaAges 6–18 - NCT04806620Recruiting
Online app study for brain inflammation lifestyle data
This study uses a digital platform (app/website) to collect lifestyle and symptom information to better understand brain inflammation. You may qualify if you have certain conditions like Long COVID, migraines, autoimmune disease, inflammatory gut issues, mood disorders, or if you are a healthy comparison person.
Delafield, WisconsinAges 2 years+ - NCT04848623Recruiting
Listening test to find voice clues of long-term health
This study is looking for “vocal biomarkers,” meaning voice patterns that could hint at how well people are doing with chronic (long-term) health conditions. Your participation would involve providing voice samples so researchers can see what voice features relate to health.
LuxembourgAges 15 years+ - NCT05970172RecruitingPhase 3
Roxadustat for anemia in kids with chronic kidney disease
This study tests roxadustat, a medicine that helps the body make more red blood cells, in children and teens with anemia caused by chronic kidney disease. It may help improve anemia and related blood counts, while also monitoring safety.
BrusselsAges 2–17 - NCT06683339Recruiting
Functional capacity in children with chronic kidney disease
This study looks at how well children with chronic kidney disease can do daily activities, like walking, climbing, and playing. It helps doctors understand how kidney disease affects a child's strength and energy.
AnkaraAges 6–18 - NCT06981585Recruiting
Physical effects in children with chronic kidney failure
This study looks at physical changes in children with chronic kidney failure compared to healthy children. If you join, you will have some physical measurements taken to help doctors understand how kidney disease affects the body.
IzmirAges 8–18 - NCT07116031RecruitingPhase 2
Belumosudil for children with chronic GVHD
This study tests a new medicine called belumosudil for children with chronic graft-versus-host disease (GVHD) that hasn't improved with at least 2 other treatments. The goal is to see if it can help control the disease and improve symptoms.
Los Angeles, CaliforniaAges 1–18 - NCT00327860Recruiting
Kidney disease in children study that follows patients over time
This is a long-term study that watches children and young adults with chronic kidney disease to understand how the illness changes and to improve care. You may be asked to complete regular visits and questionnaires, and your kidney function will be tracked over time.
Kansas City, MissouriAges 6 months–22 years - NCT06679595Enrolling by invitation
Study of care coordination programs for children with chronic illness
This study looks at programs that help children with long-term health needs get better care from different doctors and hospitals. It aims to see how well these programs work and how to improve them.
BrusselsAges Any age - NCT07107945RecruitingPhase 3
Study of empagliflozin for children with chronic kidney disease
This trial tests if empagliflozin, a daily pill, is safe and helps children ages 2–17 with chronic kidney disease (CKD). Your child may be eligible if they have reduced kidney function and elevated protein in their urine, and are already on stable kidney treatments.
Birmingham, AlabamaAges 2–17 - NCT07670611RecruitingPhase 4
Vitamin D2 alone or with calcitriol for children with liver disease
This trial compares two types of vitamin D—one is plain vitamin D2, the other is vitamin D2 plus a more active form (calcitriol)—to see which works better for children with liver problems and low vitamin D levels.
BangkokAges Up to 18 years - NCT07221604Recruiting
Goal-setting for advanced kidney disease
This trial tests a program that helps patients with advanced kidney disease, their families, and their doctors work together to set care goals. The program aims to improve communication and quality of life.
Keene, New HampshireAges 18 years+ - NCT07122921Recruiting
Sleep study in Hong Kong children with cancer
This study compares sleep patterns in children with cancer, children with other chronic illnesses, and healthy children. Researchers want to understand how cancer and its treatment affect sleep during hospitalization.
Hong KongAges 6–18 - NCT07561957Recruiting
Smartphone app to help manage chronic kidney disease
This study tests a smartphone app designed to help people with chronic kidney disease (CKD)—a condition where the kidneys don't filter blood as well as they should—follow the latest medical guidelines. The app aims to make it easier for younger adults to stay on top of their kidney health and treatment.
DublinAges 16–30 - NCT06656767Enrolling by invitation
Studying liver cell changes in chronic liver disease
This trial uses already collected liver tissue samples from adults to study how cells change over time in chronic liver disease. It could help researchers understand the disease better and find new ways to treat it.
CambridgeAges 18 years+ - NCT06324045Recruiting
Deprescribing medicines for kidney disease patients
This study looks at whether carefully reducing or stopping some medicines (deprescribing) can help people with advanced kidney disease. The goal is to improve quality of life and avoid side effects from unnecessary medications.
DohaAges 18 years+ - NCT07001631Recruiting
EMDR for pain relief in children with sickle cell disease
This trial tests if EMDR therapy can help children with sickle cell disease reduce pain interference in daily life. If you or your child has sickle cell disease and experiences significant pain, this study may offer a new way to manage it.
AmsterdamAges 6–18
Hear when a new Chronic Diseases in Children trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for chronic diseases in children?
- Yes. Clin2 currently lists 157 recruiting chronic diseases in children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic diseases in children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic diseases in children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.