Clinical trials
Chronic Diseases in Children clinical trials
Below are recruiting chronic diseases in children clinical trials, each written for real people, not researchers. We’re tracking 156 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07097961Recruiting
Rehab program for kids with lung damage after TB
This study tests a rehab program for children aged 6-17 who have lung damage from a past tuberculosis (TB) infection. The program uses mild-to-moderate physical activity to help improve their breathing and daily life.
KampalaAges 6–17 - NCT06026969Recruiting
Study on Lyme disease and baby development after pregnancy exposure
This study looks at how Lyme disease during pregnancy might affect a baby's development. It involves questionnaires and possibly an MRI of the baby's brain, done at a visit or remotely.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06324136Recruiting
Personalized diagnosis for rare kidney diseases
This trial uses genetic testing to find the cause of rare kidney diseases. It is for people with unexplained kidney problems, a family history of kidney disease, or certain findings on ultrasound. The goal is to provide a more personalized diagnosis and see if this approach is cost-effective.
FlorenceAges birth–70 years - NCT07086989Recruiting
Heart health study for kids with chronic conditions
This study looks at heart disease risk in children and young adults (ages 6-25) with long-term health conditions like certain heart, kidney, or diabetes disorders. The goal is to better understand and manage heart risks early.
BudapestAges 6–25 - NCT07382999Recruiting
Gluten-free diet and thinking skills in teens with celiac disease
This study looks at how well teenagers with celiac disease can do two things at once, like thinking and moving, and whether sticking to a gluten-free diet helps. You will be compared to healthy teens to see if there are differences.
MalatyaAges 8–18 - NCT06585774RecruitingPhase 3
Axatilimab plus steroids for new chronic GVHD
This study tests a new drug called axatilimab combined with steroids as a first treatment for chronic graft-versus-host disease (GVHD) after a stem cell transplant. It aims to see if this combination helps control symptoms better than steroids alone.
Birmingham, AlabamaAges 12 years+ - NCT06439862Recruiting
Quality of life in children with posterior urethral valves
This study looks at how children with posterior urethral valves (a condition that affects urination) feel about their quality of life as they grow up. It will help doctors understand how these children are doing emotionally and socially, so they can improve care.
Bron, BronAges 6–17 - NCT06377345Recruiting
Remote monitoring for asthma flare-ups
This trial tests a remote monitoring device that tracks your breathing while you're at home. If you have asthma and are having a flare-up today, you may be able to use a small wearable sensor and a smartphone app to help your doctor keep an eye on your condition.
SingaporeAges 7–90 - NCT05944016RecruitingPhase 3
Dapagliflozin for early Alport kidney disease in teens and young adults
This trial tests dapagliflozin, a daily medicine, to slow kidney problems in people with early-stage chronic kidney disease caused by Alport syndrome. It may help protect kidney function and reduce worsening over time.
Heidelberg, Baden-WürttenbergAges 10–39 - NCT07134595Recruiting
Comparing two peritoneal dialysis schedules in children with kidney failure
This trial tests a modified version of daily peritoneal dialysis (M-CAPD) versus the standard version (C-CAPD) for children in low-resource settings who have end-stage kidney disease. It aims to see if the modified schedule works better for clearing waste and fluid.
Manila, ErmitaAges 2–18 - NCT05858437Recruiting
Testing propionic acid to improve immune function in children with kidney failure
This study tests whether propionic acid can help the immune system work differently in children with advanced chronic kidney disease who receive regular dialysis. It may help regulate immune cells, aiming for better immune function while keeping you medically stable.
BerlinAges 12–20 - NCT06624358Recruiting
Physical activity study for teens with chronic kidney disease
This study looks at physical activity in teens with chronic kidney disease (CKD) who are not yet on dialysis or have had a transplant. It aims to understand their current activity levels and how to help them stay active safely.
Philadelphia, PennsylvaniaAges 13–18 - NCT05161078Enrolling by invitation
Studies CARPEDIEM care for newborns and babies in participating hospitals
This trial looks at how to improve outcomes for newborns and infants who receive CARPEDIEM as part of routine hospital care. It aims to see whether an interdisciplinary team approach can make treatment safer and more effective.
Palo Alto, CaliforniaAges Any age - NCT07867184Enrolling by invitation
Firefighter lung health study
This study looks at how firefighting affects your lungs over time. By tracking your health and exposures, researchers hope to find ways to prevent lung problems in firefighters.
Bethesda, MarylandAges 18–65 - NCT05236062Recruiting
Exercise during steroid treatment for GVHD
This study looks at whether doing moderate-to-vigorous exercise can reduce complications from corticosteroids in people with newly diagnosed GVHD. It may help your body tolerate steroids better, while checking exercise safety during treatment.
Boston, MassachusettsAges 18 years+ - NCT06191640Recruiting
Study of sinus disease in young children with cystic fibrosis
This study looks at sinus problems in young children with cystic fibrosis. One group of children starts a new medicine called a highly effective modulator (like Trikafta), and the other group does not take this medicine. The goal is to see how the medicine affects sinus health over time.
Aurora, ColoradoAges 2–8 - NCT06267859Enrolling by invitationEarly Phase 1
Better treatment for common childhood illnesses
This study aims to improve treatment for children with common illnesses like bronchitis and for those who get sick often, to help them recover faster and stay healthier.
Tashkent, Yunus-obad DistrictAges 3 days–15 years - NCT00032513Recruiting
Genetic study of chronic active Epstein-Barr virus disease
This research study looks for genetic factors that may explain why some people develop severe, long-lasting Epstein-Barr virus (EBV) infection. Researchers will study blood and tissue samples from patients with this rare condition, their healthy relatives, and unrelated volunteers to understand the disease better.
Bethesda, MarylandAges 1–120 - NCT07289620Recruiting
Nerve block boosters for kids' leg surgery
This study tests whether adding dexamethasone, dexmedetomidine, or both to a numbing shot (nerve block) provides better pain relief after leg surgery in children. The goal is to find which combination works best to keep your child comfortable with fewer side effects.
PoznanAges 3–12 - NCT06911749Recruiting
Using MSOT and MRI to measure bowel transit in children
This trial tests whether two imaging techniques, MSOT and MRI, can safely and non-invasively measure how long it takes for food to move through the bowels in children with chronic constipation or other bowel emptying problems. It may help doctors better understand and treat these conditions.
Erlangen, BavariaAges 1 year+ - NCT07529236Recruiting
How Children's Bowel Disease Responds After Switching IBD Medications
This study follows children who had to stop one type of IBD medicine (anti-TNFα) because it caused a skin condition called psoriasis, and were switched to a different medicine called ustekinumab. Researchers want to see how well their bowel disease is controlled with the new treatment.
Nice, FranceAges 6–17 - NCT04806347RecruitingPhase 1
Stem cell transplant using a half-matched donor for children and young adults
This trial studies a type of stem cell transplant (bone marrow transplant) that uses a donor who is only half-matched to the patient, often a parent or sibling. It is for children and young adults with certain blood diseases, including sickle cell disease, thalassemia, bone marrow failure, and immune disorders. The transplant aims to replace the diseased blood-forming cells with healthy ones from the donor.
Madison, WisconsinAges 3 months–25 years - NCT03295279Enrolling by invitation
Use of chest CT scans from WTC Health Plan participants
This study creates a research archive of chest CT scan images from people enrolled in the World Trade Center (WTC) Health Plan program at Mount Sinai. It may help doctors and researchers better understand and track chest health over time using existing scan images.
New York, New YorkAges 18 years+ - NCT07470502Recruiting
Study of infliximab for children and teens with IBD
This trial is looking at children and teenagers with Crohn's disease or ulcerative colitis who are starting a biologic medicine called infliximab. It aims to learn more about how this treatment works in young patients.
Florence, ItalyAges 3–18
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Common questions
- Are there clinical trials for chronic diseases in children?
- Yes. Clin2 currently lists 156 recruiting chronic diseases in children studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic diseases in children trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic diseases in children trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.