Clinical trials
Chronic Postoperative Pain clinical trials
Below are recruiting chronic postoperative pain clinical trials, each written for real people, not researchers. We’re tracking 301 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06721819RecruitingPhase 3
Sleep and brain training before heart surgery to prevent delirium
This study tests whether a combination of sleep therapy, brain games, and light exercise before heart surgery can help prevent confusion or disorientation (delirium) after the operation. Participants will be asked to use a tablet and fitness tracker daily for about an hour before their surgery.
Boston, MassachusettsAges 60 years+ - NCT07226700RecruitingPhase 3
Suzetrigine for pain after hip replacement surgery
This study tests an investigational pain medicine called suzetrigine to see how well it controls pain after total hip replacement surgery. It is for adults 18–80 who are having a first-time hip replacement and can receive spinal anesthesia.
New York, New YorkAges 18–80 - NCT04811209Recruiting
Testing better pain control and recovery after orthopedic surgery
This trial looks at how well a pain-control plan works after certain orthopedic surgeries and how it affects recovery and patient-reported outcomes. It may help determine what level of pain relief is meaningful to patients after surgery.
Toronto, OntarioAges 18–80 - NCT05179928Recruiting
Numbing injections for less pain after belly surgery
This trial compares two different numbing injection techniques to help control pain after surgery above the belly button. It may help people who qualify have better or longer-lasting pain relief with fewer side effects.
Damanhūr, El-BeheiraAges 21–60 - NCT06653803Recruiting
Nerve blocks for pain after chest wall surgery
This trial compares two types of nerve blocks (rhomboid intercostal and retrolaminar) to see which provides better pain relief after a type of chest surgery called thoracoscopic sympathectomy. If you are having this surgery, you may be eligible to join.
Damanhūr, El-BeheiraAges 18–60 - NCT07209345Recruiting
Scalp pain relief after brain surgery
This trial tests whether numbing the scalp before brain surgery can reduce pain afterward. You would receive a painkiller injection in your scalp before your surgery begins.
BeijingAges 18–64 - NCT07208799RecruitingPhase 2
Steroid comparison for jaw fracture recovery
This trial compares two steroid medicines (dexamethasone and methylprednisolone) to see which one better reduces swelling, pain, and other symptoms after surgery for a broken lower jaw near the chin. It could help you recover faster and with less discomfort.
Multan, Punjab ProvinceAges 18–40 - NCT07666646Recruiting
Nerve block comparison for lung function after gallbladder surgery
This trial compares two types of nerve blocks to see which one better preserves lung function after laparoscopic gallbladder removal. It may help patients recover breathing ability more quickly after surgery.
Kayseri, KocasinanAges 18–70 - NCT06704698Recruiting
Pain relief after esophageal surgery: comparing two nerve blocks
This trial compares two types of nerve blocks (paravertebral and epidural) to see which provides better pain relief after esophagectomy. The goal is to find the safest and most effective way to manage pain for patients undergoing this surgery.
Hangzhou, ZhejiangAges 18–80 - NCT07401134RecruitingPhase 4
Pain relief study after vaginal surgery using witch hazel and spray
This trial tests a pain relief routine using witch hazel pads and a numbing spray after vaginal surgery. The goal is to see if using these products together helps with recovery and reduces the need for stronger pain medicine.
Miami, FloridaAges 18 years+ - NCT07094386Recruiting
Pain relief study after open upper abdominal surgery
This trial compares two types of nerve blocks to control pain after open upper abdominal surgery. It aims to find which block works better and may help you recover with less pain.
CairoAges 18–60 - NCT07388953Recruiting
Nerve block for better pain relief after colon surgery
This study tests adding a special nerve block (peripheral autonomic block) to a standard abdominal wall block to see if it provides better pain relief after minimally invasive left-sided colon surgery. It may help patients experience less pain and use fewer pain medications.
Belo Horizonte, Minas GeraisAges 18–80 - NCT07081373Recruiting
Repeat dose of liposomal bupivacaine for pain after anal fistula surgery
This trial tests if a repeat dose of liposomal bupivacaine (a long-acting numbing medicine) helps reduce pain after surgery for anal fistula. It may be a good option if you are having this surgery and want better pain control.
Guangzhou, GuangdongAges 18–60
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Common questions
- Are there clinical trials for chronic postoperative pain?
- Yes. Clin2 currently lists 301 recruiting chronic postoperative pain studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic postoperative pain trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic postoperative pain trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
- Postoperative Pain
- Postoperative Pain, Acute
- Postoperative Pain Management
- Total Knee Arthroplasty (Postoperative Pain)
- POSTOPERATIVE DELIRIUM AND POSTOPERATIVE COGNITIVE DECLINE
- Postoperative Pain After Endodontic Treatment
- Postoperative Pain Following Knee Arthroplasty
- Postoperative Pain Management in Oral Surgery
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.