Clinical trials
Chronic Venous Disease clinical trials
Below are recruiting chronic venous disease clinical trials, each written for real people, not researchers. We’re tracking 69 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07165340Enrolling by invitationPhase 1/Phase 2
Physiotherapy for leg swelling from vein disease
This study tests whether adding a special physiotherapy program can help reduce leg swelling in people with vein disease. If you have swelling from varicose veins or other vein problems and have not tried certain treatments before, you may be able to join.
Houston, TexasAges 18 years+ - NCT07737236Recruiting
Ruscus study for symptom relief in chronic vein problems
This study tests a natural plant extract called Ruscus to see if it helps control symptoms of chronic venous insufficiency, a condition where leg veins have trouble moving blood back to the heart. It is for people who are already starting this treatment as part of their regular care.
Ankara, AnkaraAges 18–75 - NCT05628948Recruiting
Donate blood for a heart and metabolism research biobank
This study builds a “biobank,” which is a collection of blood and related samples, to support future research on heart and metabolic (sugar/body-fat) conditions. It may help researchers better understand these diseases and improve future prevention and treatments.
Cleveland, OhioAges 18 years+ - NCT06798766Recruiting
Understanding darker skin tones and vein disease care
This study looks at how people with darker skin tones experience chronic venous insufficiency (a condition that affects blood flow in the legs) and aims to improve how it's diagnosed and treated. It involves two parts: one is sharing your experience through an interview, and the other includes a skin check and photos at the hospital.
London, LondonAges 18 years+ - NCT06738394Recruiting
Exercise study for older adults with kidney disease
This study tests whether a supervised exercise program can help older adults with chronic kidney disease improve their physical function and stay active. You have to be able to do exercise and not be on dialysis.
Winston-Salem, North CarolinaAges 65–100 - NCT04896047Recruiting
Test whether FGF19 helps non-diabetic kidney disease
This study looks at FGF19 to see if it can improve chronic kidney disease in people who do not have diabetes. Participants may receive FGF19 (and may need extra testing such as muscle biopsies).
Pierre-BéniteAges 18–70 - NCT06752577Recruiting
Stem cell treatment for chronic kidney disease safety study
This study tests whether a single infusion of stem cells from bone marrow is safe for people with chronic kidney disease (CKD). It aims to see if this treatment can help slow kidney function loss.
Jacksonville, FloridaAges 18 years+ - NCT04487314Recruiting
Study of chronic vein disease over time
This study follows people (and certain close family members) to document how chronic vein problems develop and change over time. You would get yearly checkups and ultrasound scans to track the natural course of the condition.
Saint PetersburgAges 10 years+ - NCT03035747Recruiting
Registry for treatment of varicose veins
This study collects information about people who have varicose veins with abnormal backflow in the leg veins. It’s meant to track how treatments for chronic venous problems are working over time, which can help improve care for others in the future.
Saint PetersburgAges 18 years+ - NCT06015620Recruiting
Health changes after mini gastric bypass surgery
This study looks at how mini gastric bypass surgery helps with obesity-related health problems and changes in body composition. It aims to see if patients experience improvements in conditions like diabetes or high blood pressure.
Bhubaneswar, OdishaAges 18–65 - NCT06225544RecruitingPhase 2
Lumasiran for high oxalate patients on hemodialysis
This trial tests a drug called Lumasiran to lower oxalate levels in patients on hemodialysis (a type of kidney dialysis). It may help reduce complications from high oxalate, which can damage organs.
BerlinAges 18–80 - NCT05249634RecruitingPhase 2
Testosterone treatment study for men with chronic kidney disease
This Phase 2 study tests whether testosterone therapy can help men with chronic kidney disease who have low testosterone and related symptoms. It looks to see if treatment is safe and beneficial, while carefully checking heart, blood, prostate, and clotting risks.
St Louis, MissouriAges 18–85 - NCT07335861Recruiting
Hyalomatrix for healing venous leg ulcers
This trial tests a special gel-like dressing (Hyalomatrix) to see if it helps heal leg ulcers caused by poor blood flow in the veins. It may be a good option if you have a chronic venous leg ulcer that hasn't healed much despite standard care.
Alexandria, LouisianaAges 18 years+ - NCT00001405Recruiting
Blood Cell Collection Study for Immune and Blood Disorders
This study collects blood cells and bone marrow from people with immune system or blood disorders, and from healthy volunteers. Researchers will study these cells and may convert them into special stem cells (iPS cells) to better understand diseases and develop treatments.
Bethesda, MarylandAges 18–70 - NCT07592000RecruitingPhase 1/Phase 2
New Treatment for Type 1 Diabetes With Kidney Disease
This study tests a new experimental medication for people with type 1 diabetes who experience dangerous low blood sugar episodes and have early-stage kidney disease. The trial aims to help improve blood sugar control and reduce these risky episodes.
Miami, FloridaAges 18–70 - NCT06942910RecruitingPhase 2
New combination therapy for chronic kidney disease with high proteinuria
This study tests a combination of two drugs (zibotentan and dapagliflozin) compared to dapagliflozin alone in people with chronic kidney disease and high protein in their urine. The goal is to see if the combination works better at protecting your kidneys.
AramilAges 18 years+ - NCT06663722RecruitingPhase 2
Axatilimab and ECP for chronic graft-versus-host disease
This trial tests a new drug (axatilimab) combined with a light-based blood treatment (ECP) for people with chronic graft-versus-host disease (cGVHD) after a stem cell transplant. It's for those who have already tried at least 2 other treatments or need high doses of steroids.
San Francisco, CaliforniaAges 12 years+ - NCT05679024RecruitingPhase 3
Apixaban to prevent stroke in atrial fibrillation and kidney failure
This trial tests apixaban (a blood thinner) to prevent stroke in people with atrial fibrillation or atrial flutter who have very poor kidney function or are on dialysis. If you qualify, you may help researchers find a safer way to lower stroke risk for this higher-risk group.
HelsinkiAges 18 years+ - NCT07760363Recruiting
Foot exercise device for leg swelling
This study tests if using a foot pedal device while lying down can help reduce leg swelling in the hospital. It aims to see if this simple exercise can improve comfort and outcomes for people with fluid buildup.
Tulsa, OklahomaAges 18 years+ - NCT07233616Recruiting
Radiofrequency ablation for chronic venous insufficiency in patients 80+
This study tests whether a procedure called radiofrequency ablation (using heat to close faulty veins) is safe and effective for people aged 80+ with chronic venous insufficiency. It aims to relieve symptoms like leg swelling, skin changes, or ulcers.
Chengdu, SichuanAges 80 years+ - NCT06925217Recruiting
Closed-loop insulin for type 2 diabetes and kidney disease
This study tests whether a special type of insulin delivery system (closed-loop) can help people with type 2 diabetes and chronic kidney disease. You'll wear a continuous glucose monitor and insulin pump, and researchers will track how your kidneys respond over time.
Lausanne, Canton of VaudAges 18 years+ - NCT07478406Enrolling by invitation
Pelvic floor and vein health connection study
This study looks at how pelvic floor muscles relate to leg vein problems (venous insufficiency). You may benefit if you have vein issues and are willing to try telerehabilitation.
Istanbul, IstanbulAges 30–65 - NCT06062199Recruiting
Study on easier first-attempt IV insertion
This trial tests a new scoring method called A-DIVA to help nurses find a vein on the first try when starting an IV (VVP). It may reduce multiple needle sticks and improve comfort.
Clermont-FerrandAges 18 years+ - NCT04944615Recruiting
IVUS-guided stent placement for blocked heart artery using longer guidance
This trial compares two ways to place a stent (a small mesh tube) for a completely blocked heart artery: using an IVUS camera inside the artery versus using a standard x-ray approach. It may help people get better heart outcomes by improving how accurately the stent is placed in long-term blockages.
BeijingAges 18 years+
Hear when a new Chronic Venous Disease trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for chronic venous disease?
- Yes. Clin2 currently lists 69 recruiting chronic venous disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a chronic venous disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a chronic venous disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.