Clinical trials
Clinical High Risk for Psychosis clinical trials
Below are recruiting clinical high risk for psychosis clinical trials, each written for real people, not researchers. We’re tracking 19 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05398120Recruiting
Skills group for teens at high risk for psychosis
This study offers a skills-based group program for teens who are considered at high risk of developing a psychotic disorder. It aims to help young people cope and possibly lower the impact of early warning symptoms.
Pittsburgh, PennsylvaniaAges 13–18 - NCT05509998Enrolling by invitation
Improving early care for untreated psychosis
This trial looks at ways to help people get treatment sooner after psychosis starts. It focuses on how screening and better communication across care teams may reduce the time before treatment begins.
New York, New YorkAges 12–30 - NCT05968560Recruiting
Online therapy to help youth at risk for psychosis
This trial tests a telehealth (video/phone) version of cognitive behavioral therapy to help young people who are at risk for developing psychosis. It may help by teaching skills to reduce symptoms and improve coping, with support from a key family or close person.
New York, New YorkAges 14–25 - NCT06582901Recruiting
Support for youth at clinical high risk for psychosis in Tunisia
This study tests a support program for young people in Tunisia who show early signs of possible psychosis. It aims to help them before more serious symptoms develop.
TunisAges 14–28 - NCT07226895RecruitingPhase 1/Phase 2
Study of MT1988 for people at high risk for psychosis
This trial tests a new drug called MT1988 in people who show early warning signs of psychosis. Researchers want to see if it changes certain markers in the body related to mental health.
Irvine, CaliforniaAges 17–30 - NCT06802952Recruiting
Personalized magnetic brain stimulation for early psychosis risk
This study tests whether a type of magnetic brain stimulation (rTMS) can help people who are at high risk for psychosis. The stimulation is personalized using a brain scan called magnetoencephalography (MEG) to target the right areas.
ShanghaiAges 13–35 - NCT05827549RecruitingPhase 2
Blinatumomab for relapsed ALL, matched by risk group
This Phase 2 study tests how well blinatumomab works for children and adults whose acute lymphoblastic leukemia (ALL) has come back. It also looks at whether results differ based on the patient’s relapse “risk group.”
DaeguAges 1–22 - NCT06542640Recruiting
Understanding brain changes in youth at risk for psychosis
This research study looks at how the brain changes in young people who are at high risk for developing psychosis. It aims to find better ways to predict and prevent psychosis by using brain imaging and thinking tests.
Shanghai, Shanghai MunicipalityAges 15–35 - NCT06640803Recruiting
Early psychosis risk stepped-care program
This study offers a step-by-step care program for teens and young adults at high risk for psychosis. It aims to provide the right level of support early on to prevent or reduce the severity of symptoms.
Elk Grove, CaliforniaAges 12–25 - NCT06649552Recruiting
French validation of a psychosis risk questionnaire for teens
This study is testing a new French version of a questionnaire (SPI-CY) that helps doctors better understand early signs of psychosis in teenagers. If you are 12 to 17 and already being checked for these signs, you may be able to help improve the tool.
LilleAges 12–17 - NCT06774417Recruiting
Digital strategies to help young people seek help for mental health
This trial tests a digital tool designed to help young people recognize early signs of mental health conditions and take steps toward getting help. It may be a good fit if you are between 12 and 29, live near certain research sites, and can complete a short screening questionnaire in English.
New York, New YorkAges 12–29 - NCT06774430Recruiting
Digital outreach for young people at risk of psychosis
This study tests a digital program designed to encourage young people to seek help for early signs of psychosis. It aims to see if online messages can increase connections to care.
New York, New YorkAges 12–29 - NCT07093671Recruiting
Therapy for Teens and Young Adults at Risk for Psychosis
This trial tests a type of therapy called Mentalization Based Treatment (MBT) for young people who are at high risk for developing psychosis. The therapy helps you understand your own and others' thoughts and feelings, with the goal of reducing distress and preventing psychosis.
LausanneAges 14–30 - NCT07499934Recruiting
Mindfulness experience for young people at risk of psychosis
This study explores how young people who are at high risk for psychosis or have had a first episode experience mindfulness. It uses interviews to understand their personal experience, which could help improve future treatments.
LaxouAges 15–30 - NCT03970005Enrolling by invitation
Step-based program for teens with early signs of psychosis
This trial tests a staged (“step-based”) mental health program for people ages 12–25 who have early warning signs that could develop into psychosis. It may help by targeting symptoms early and reducing the chance of worsening over time.
Columbus, OhioAges 12–25 - NCT05131035Recruiting
Trial for thinking-speed training to lower psychosis risk
This study targets problems with “processing speed,” or how fast your brain handles information, to see if it can improve social functioning and lower the risk of developing full psychosis. It’s for people who are considered at high risk for psychosis but do not already have schizophrenia.
Glen Oaks, New YorkAges 14–20 - NCT06151158Recruiting
Preventing suicide in high-risk youth after a crisis visit
This study tests a program to help teens and young adults who have had thoughts of suicide or made an attempt. The program provides extra support after they leave the hospital or treatment program to help keep them safe.
St. Petersburg, FloridaAges 12–24 - NCT07346014Recruiting
Sleep therapy for college students at risk of suicide
This study tests if improving sleep can help college students who are already getting mental health treatment for suicidal thoughts. You will try light therapy or sleep schedule changes to see if it reduces suicide risk.
Pittsburgh, PennsylvaniaAges 18–25 - NCT06329245Recruiting
Tracking social skills and brain growth in infants at risk for autism
This study looks at how social behaviors and brain connections develop in infants who have a higher or lower chance of developing autism. It helps doctors understand early signs and may lead to better support for children and families.
ShanghaiAges birth–1.5 years
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Common questions
- Are there clinical trials for clinical high risk for psychosis?
- Yes. Clin2 currently lists 19 recruiting clinical high risk for psychosis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a clinical high risk for psychosis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a clinical high risk for psychosis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.