Clinical trials
Cognition clinical trials
Below are recruiting cognition clinical trials, each written for real people, not researchers. We’re tracking 2,028 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05553197Recruiting
Track mood during therapy using smartphone check-ins
This study looks at how mood changes between therapy sessions by having you answer short mood questions on your smartphone. It may help the researchers understand what support works best for people with mild-to-moderate depression.
Zurich, Canton of ZurichAges 18 years+ - NCT05615610Recruiting
Electrical stimulation therapy for brain and arm recovery after stroke
This trial tests whether painless electrical nerve stimulation placed on the skin can improve thinking (cognitive function) and arm movement in people living with long-term stroke. If you qualify, you may receive this non-drug therapy and be assessed for changes in memory/thinking and upper-limb movement.
Hong KongAges 50–80 - NCT05107947Recruiting
Dynamic room lighting to improve sleep and daily body rhythm
This study tests whether changing the light in a hospital room can improve sleep and help your body clock work better in older adults. It may be most helpful if sleep problems or irregular daily rhythms are affecting you in the hospital.
MalmöAges 65 years+ - NCT05117463Recruiting
Balance testing while doing thinking tasks and eye-movement training
This study tests how well your balance and coordination work while you do a thinking task, using special visual (eye-movement) stimulation. It may help researchers understand why some people have balance problems and how training could improve safety.
Greenville, North CarolinaAges 25–85 - NCT05136703Recruiting
Study depression treatment effects in people living with HIV
This study looks at how depression and its treatment may affect the brain and immune-related body systems in people with HIV. You may be eligible if you have depression and a well-controlled HIV viral load, and you can safely complete brain MRI scans.
Coral Gables, FloridaAges 18 years+ - NCT04989608Recruiting
Study links brain scan results with thinking after a TIA
This study looks at how brain imaging findings match up with thinking and memory in people after a TIA (a temporary stroke-like event). If you join, your role is mainly to contribute data from brain scans soon after the event, plus study questionnaires.
CaenAges 60 years+ - NCT05232383Recruiting
Testing how light at night affects sleep, alertness, and mood
This study looks at how exposure to artificial light changes sleep, daytime alertness, thinking skills, mood, and the body’s daily (circadian) rhythm. You may be asked to follow a strict sleep schedule and avoid certain substances so researchers can measure changes.
StrasbourgAges 18–40 - NCT05256745RecruitingPhase 1/Phase 2
A medicine to protect the heart during breast cancer chemotherapy
This early-phase study tests azeliragon to lower the risk of chemotherapy-related heart damage in women with early-stage breast cancer. Participants get their planned standard chemotherapy, plus the study medicine, and are monitored for safety and heart health.
Washington D.C., District of ColumbiaAges 18 years+ - NCT05124132Enrolling by invitation
Study of resilience and brain health after an earlier parent study
This trial looks at how resilience (how well people cope with stress) and brain health change over time in older adults who already joined an earlier study. You may be eligible if you participated in that “parent study.”
St Louis, MissouriAges 65 years+ - NCT05324579Recruiting
Studying how the brain supports social understanding
This study looks at how brain activity relates to social thinking. It may help researchers better understand the brain processes involved in social cognition by using brain testing during a procedure.
Boston, MassachusettsAges 18 years+ - NCT05273970Enrolling by invitation
Brain recording study during electrode surgery for drug-resistant epilepsy
This study uses special brain recordings done during electrode implantation to better understand brain activity in people whose symptoms are hard to control with medications. The goal is to help doctors improve how they evaluate and treat certain brain or nerve conditions.
Phoenix, ArizonaAges 18–80 - NCT05878002Recruiting
Tests thinking, movement, and sleep after clot removal stroke
This study looks at thinking skills, body movement, and sleep patterns in adults after a specific type of stroke treated with a clot-removing procedure. It may help doctors better understand what changes happen after treatment and how to measure them.
RomeAges 18 years+ - NCT02559752Recruiting
Computer brain testing during proton radiation for childhood tumors
This trial studies how children’s thinking and learning skills change while they receive proton beam radiation for a brain/spinal cord tumor. It uses computer-based cognitive tests to better understand brain effects during treatment, which may help future care.
St Louis, MissouriAges 4–21 - NCT04956549Recruiting
Exercise program for early memory loss in African Americans
This study tests whether a structured exercise program can lower Alzheimer’s risk in older African American adults who have mild cognitive impairment (MCI). You’ll be placed by chance into an exercise group or a comparison group and attend group sessions for about a year.
Baton Rouge, LouisianaAges 60 years+ - NCT04280458Recruiting
Intensive movement and thinking rehab for children with severe disabilities
This trial tests an intensive rehabilitation program to improve both movement abilities and daily function in children with severe, long-term disability due to early brain injury. It may help children gain better adaptive skills and independence through structured therapy.
Hyères, VarAges 4–13 - NCT04041154Recruiting
Study of how the brain senses effort cost
This study asks people to do tasks while the researchers measure brain activity, to understand how the brain represents the “cost” of effort. It may help improve understanding of effort-related problems in mental and neurological conditions.
Baltimore, MarylandAges 18–35 - NCT04165746Recruiting
Early care program for very young children in foster systems
This study looks at how an early support program affects the development of infants who are newly entering institutional care or foster care in the São Paulo area. It may help families and caregivers support healthy growth during a critical first period.
São Paulo, São PauloAges Up to 2 years - NCT04253379Recruiting
Study of social understanding in children with epilepsy
This study looks at how children with epilepsy understand social cues, compared with other children the same age. You may be asked to complete simple thinking and social tasks to see what differences exist and what they might mean.
ReimsAges 6–12 - NCT04480203Recruiting
Digital coping tools after new breast cancer diagnosis
This trial tests two online programs designed to help people cope after being diagnosed with breast cancer. It may help you manage stress and emotions during treatment or recovery.
OsloAges 20–69 - NCT05593627RecruitingPhase 4
Lithium to improve sleep and thinking after heart surgery
This trial tests whether lithium carbonate can improve sleep and thinking (cognitive function) after heart valve surgery that uses a heart-lung machine. It may help some people who have trouble sleeping or thinking after surgery, but it excludes people with significant sleep or thinking problems before surgery.
Shenyang, LiaoningAges 18–65 - NCT07166432Recruiting
New brain stimulation for thinking and balance problems in Cushing syndrome
This trial tests a new, minimally invasive brain stimulation technique for people with Cushing syndrome who have developed a condition called cerebellar cognitive affective syndrome (CCAS). It aims to improve both thinking skills and movement coordination.
BeijingAges 18–85 - NCT06175000RecruitingPhase 2
Maintenance obinutuzumab for central nervous system lymphoma
This trial tests whether a maintenance drug called obinutuzumab can help prevent relapse in people with primary central nervous system lymphoma (a rare lymphoma in the brain or spine) who have already responded to initial chemotherapy. It is for those who have achieved at least a partial or complete response to their first treatment.
New York, New YorkAges 18 years+ - NCT06520306Enrolling by invitation
Ropivacaine with methylene blue for hip surgery pain
This trial tests if adding different amounts of methylene blue to a standard numbing medicine (ropivacaine) can improve pain relief, thinking ability, and hip movement after hip replacement surgery.
TaizhouAges 60–85 - NCT04731519Recruiting
Group treatment to help Veterans after a recent suicidal crisis
This trial studies a “recovery-oriented” group therapy for Veterans who had a suicide attempt or started planning within the last year. It aims to help reduce risk and improve coping and recovery after a post-acute suicidal episode.
The Bronx, New YorkAges 18 years+
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Common questions
- Are there clinical trials for cognition?
- Yes. Clin2 currently lists 2,028 recruiting cognition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.