Clinical trials
Cognition Improvement clinical trials
Below are recruiting cognition improvement clinical trials, each written for real people, not researchers. We’re tracking 110 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07708246Recruiting
Parent-led social skills program for children with autism
This trial tests whether a parent-led program can help children with autism improve social understanding. If you join, you will learn to use play-based activities at home with your child, with support from a clinician.
Shanghai, Shanghai MunicipalityAges 4–8 - NCT07000500Enrolling by invitation
Nutritional supplement for memory decline in older adults
This trial tests whether a nutritional supplement can help slow or improve memory loss in older adults who have mild cognitive decline (noticeable changes in thinking skills that are not yet dementia). You will take a daily supplement and attend regular check-ups.
Vila Nova de Famalicão, Braga DistrictAges 65 years+ - NCT06598163Recruiting
Cognitive training app for mild memory problems
This trial tests a mobile app called Five Lives MED to see if it can improve thinking and memory in people with mild cognitive impairment (MCI). You can join if you have MCI and are 50 or older.
Paris, Île-de-France RegionAges 50 years+ - NCT07609030Recruiting
Brain Training During CAR-T Cell Cancer Treatment
This study tests whether special brain exercises can help protect thinking and memory skills during CAR-T cell therapy—a newer cancer treatment for certain blood cancers. Researchers want to see if training your brain during treatment reduces side effects on memory and mental function.
Columbus, OhioAges 18 years+ - NCT07504276Recruiting
Remote rehab vs in-person rehab for stroke recovery
This study compares doing brain-training exercises at home on a digital device versus going to a clinic after a stroke. It aims to see which method better helps improve memory, thinking, and daily function.
Islamabad, Punjab ProvinceAges 50–80 - NCT06292637Recruiting
Faith-focused counseling for depression in African Americans
This study tests whether adding a faith-based support group to a counseling program helps African American adults with depression feel better. You would join group sessions that combine talking through your thoughts (cognitive behavioral therapy) with fellowship and spiritual support.
Madison, WisconsinAges 18 years+ - NCT07272174Recruiting
Exercise during perimenopause to boost thinking and memory
This trial tests whether a strength-training program can help improve memory and thinking for women going through perimenopause. If you are between 40 and 55, still have your uterus, and notice changes in your memory, you may be able to join.
Vancouver, British ColumbiaAges 40–55 - NCT07747181Recruiting
Brain stimulation and yoga for thinking skills in psychosis
This study tests whether combining brain stimulation with yoga can improve thinking and memory in people with psychosis. It may help with daily functioning and quality of life.
Hung Hom, KowloonAges 18–65 - NCT07446478Recruiting
TIS for improving thinking problems in schizophrenia
This trial tests if a brain stimulation technique called transcranial electrical stimulation (TIS) can help improve cognitive problems (like memory and attention) in people with schizophrenia. You may join if you are between 18 and 50, have had schizophrenia for no more than 8 years, take 1-2 antipsychotic medicines, and have some trouble with daily activities.
Changsha, HunanAges 18–50 - NCT07546877Recruiting
Brain Stimulation to Improve Memory After Stroke
This study tests whether a non-invasive brain stimulation technique called high-frequency repetitive transcranial magnetic stimulation (rTMS) can help improve thinking and memory problems that occur after a stroke. If you've had a stroke in the past year and are experiencing cognitive difficulties, this trial may help restore some of your mental abilities.
JinanAges 35–75 - NCT05890183Recruiting
Telehealth exercise and brain training after a first psychosis episode
This trial tests whether a combination of at-home (telehealth) aerobic exercise and computer-based cognitive training can improve thinking and day-to-day function after a first episode of schizophrenia-spectrum illness. It may help by strengthening attention and learning skills after the initial psychotic episode.
Los Angeles, CaliforniaAges 18–45 - NCT07647380Recruiting
Brain Stimulation to Help Thinking in Schizophrenia
This trial tests a non-invasive brain stimulation technique called transcranial electrical stimulation (TIS) to improve thinking and memory problems in people with schizophrenia. Researchers want to see if this treatment, combined with antipsychotic medications, can help you think more clearly and function better in daily life.
Changsha, HunanAges 18–50 - NCT05540613Recruiting
Tai Chi versus exercise to help thinking in mild memory loss
This study compares Tai Chi with conventional exercise to improve thinking and memory in older adults who have mild cognitive impairment. If you qualify, you may be asked to do a supervised exercise program and be tested on thinking abilities over time.
Hong KongAges 50 years+ - NCT06727773RecruitingPhase 2
Memantine and exercise to protect thinking during chemo for breast cancer
This study tests whether a medicine called memantine combined with a structured exercise program can help protect your thinking and memory during chemotherapy for breast cancer. It may also help understand how these treatments work in the body.
Chapel Hill, North CarolinaAges 18 years+ - NCT03836950RecruitingPhase 1/Phase 2
Brain stimulation to improve thinking in Parkinson’s
This trial studies a noninvasive treatment called rTMS to help improve thinking and memory in people with Parkinson’s who have mild cognitive problems. It may help strengthen brain function, but it also has strict safety and eligibility rules to protect against seizure and metal-related risks.
Chicago, IllinoisAges 50 years+ - NCT07145294RecruitingPhase 1/Phase 2
Stem cell therapy to improve thinking after stroke
This trial tests whether tiny particles from stem cells can help people recover thinking and memory after a recent stroke. Doctors will check if the treatment is safe and if it boosts brain function.
ShanghaiAges 18 years+ - NCT06238492Recruiting
Boosting brain speed after spinal cord injury
This trial tests a program to help improve how quickly your brain processes information after a recent spinal cord injury. It focuses on people who are about 6 months post-injury.
Englewood, ColoradoAges 18–59 - NCT07452939Recruiting
Brain stimulation to help memory after ICU delirium
This study tests if a noninvasive brain stimulation technique called theta burst stimulation can improve thinking and memory problems that can happen after a stay in the ICU with delirium. It may help people who are still having cognitive issues a few months after leaving the hospital.
Gainesville, FloridaAges 50–75 - NCT07395609Recruiting
Brain stimulation to boost memory, movement, and mood in older adults
This study tests whether high-frequency electrical stimulation of the brain can help improve thinking, movement, and mood in older adults who may or may not have early signs of memory decline. Participants will get sessions of stimulation and complete thinking and walking tasks.
Gainesville, FloridaAges 65–89 - NCT07733726Enrolling by invitation
Dual-Task Mouth and Memory Training for Oral Frailty
This study tests a program that combines mouth exercises with memory tasks to see if it can improve both chewing, swallowing, and thinking skills in people who have oral frailty and some memory decline.
KowloonAges 50 years+ - NCT05081596Recruiting
Primary care program for mood and thinking in early Alzheimer’s
This trial tests a psychosocial (talk/behavior/support) program delivered through primary care to improve thinking and depression symptoms in older adults with mild cognitive problems and early Alzheimer’s. It may help if you have early memory/thinking changes plus mild depressive symptoms and you can work with a caregiver or study partner.
White Plains, New YorkAges 60 years+ - NCT07759115Recruiting
Music program to improve thinking in people with multiple sclerosis
This study tests a music-based program to see if it can help improve thinking and memory in people with multiple sclerosis. It is a small feasibility study to see if the program is practical and helpful.
Austin, TexasAges 18–80 - NCT03614962Recruiting
Warmth and TENS to improve thinking in dementia
This study tests whether using a warmth treatment and a gentle electrical nerve-stimulation device (TENS) can improve thinking and memory in people with mild to moderate dementia. It may help by supporting brain and nerve function, alongside your usual care.
Hong KongAges 65 years+ - NCT04490733Recruiting
Test dual-task walking to improve thinking in colorectal cancer
This study looks at a walking exercise that makes you do two tasks at once (for example, walking while focusing on something) to see if it can improve thinking and memory. It is for people newly diagnosed with early to mid-stage colorectal cancer, and excludes people with other cancers or cancer coming back.
TaipeiAges 40–75
Hear when a new Cognition Improvement trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for cognition improvement?
- Yes. Clin2 currently lists 110 recruiting cognition improvement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognition improvement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognition improvement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.