Clinical trials
Cognition clinical trials
Below are recruiting cognition clinical trials, each written for real people, not researchers. We’re tracking 1,981 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04694534Recruiting
Serious game program to help thinking skills in multiple sclerosis
This trial tests whether a computer “serious game” can improve thinking and memory skills in people with multiple sclerosis (MS). It’s designed for adults who report thinking problems and show weaker-than-average results on specific brain tests.
Arras, Hauts-de-FranceAges 18–65 - NCT06524505Recruiting
Deep brain stimulation for bipolar depression
This trial tests a non-invasive brain stimulation technique called deep transcranial magnetic stimulation (dTMS) to see if it improves depression in people with bipolar disorder. dTMS uses magnetic pulses to stimulate brain areas involved in mood regulation.
TianjinAges 18–65 - NCT06529744Recruiting
Using blood tests to better diagnose early dementia
This study is testing whether simple blood tests can help doctors better understand the type and progression of memory or thinking problems in people with early dementia. It aims to improve confidence in the diagnosis and future outlook.
North York, OntarioAges 30–95 - NCT06502964RecruitingPhase 2
ALTO-101 study for schizophrenia cognitive symptoms
This study tests an experimental medication called ALTO-101 for people with schizophrenia who also have cognitive impairment (memory or thinking problems). It aims to see if the drug can improve these symptoms while you continue your current antipsychotic treatment.
Garden Grove, CaliforniaAges 21–55 - NCT06497894RecruitingPhase 4
Hormone therapy for sleep in late menopause
This trial tests whether hormone replacement therapy (HRT) can improve sleep for women in late menopause who have insomnia. If you are in late menopause and struggle with poor sleep, this study may offer a treatment option.
BernAges 45–69 - NCT06507189Recruiting
How exercise affects older adults: a study
This study looks at how different older adults respond to exercise. It will help researchers understand why some people benefit more than others. You will be asked to do supervised exercise sessions and tests over about 6 months.
Pensacola, FloridaAges 60 years+ - NCT06496425Recruiting
Exercise for protecting memory in older adults
This study tests whether a 12-month exercise program can help protect memory and thinking skills in older adults who have noticed changes in their memory. You would be asked to exercise at home and attend some group classes.
Atlanta, GeorgiaAges 65 years+ - NCT06501495Recruiting
Brain waves and memory in aging and Alzheimer's
This study looks at how brain waves (EEG) change during normal aging and early Alzheimer's disease. It compares three groups: people with early-stage Alzheimer's, healthy older adults, and healthy young adults. The goal is to understand how memory and thinking problems relate to slow brain wave activity.
ParisAges 18–85 - NCT06497816Recruiting
COPD Study: Health, Thinking, and Physical Abilities
This study looks at how health knowledge, physical abilities, thinking skills, and daily habits affect quality of life in people with COPD. It aims to find ways to better support patients.
Ankara, AnkaraAges 40 years+ - NCT06511674Recruiting
Nerve pain risk study for cancer patients
This study looks at why some people with cancer develop nerve pain (neuropathic pain) during treatment. By tracking your health and symptoms, researchers hope to find ways to predict and prevent this side effect.
AjaccioAges 18 years+ - NCT06507488Recruiting
Daphnetin Capsule for Mild Cognitive Issues From Blood Vessels
This trial tests a capsule called daphnetin for people with mild thinking and memory problems linked to blood vessel health. The goal is to see if it helps improve or slow down these changes.
Shenyang, LiaoningAges 50–80 - NCT06489548RecruitingPhase 2
Foralumab for Early Alzheimer's Disease
This study tests an experimental drug called Foralumab, which aims to calm overactive immune cells in the brain linked to Alzheimer's. It may help slow memory loss in people with early-stage Alzheimer's.
Boston, MassachusettsAges 60–85 - NCT06489873Recruiting
Lutein, Zeaxanthin, and Fish Oil for Macular Health
This study tests whether taking daily supplements of lutein, zeaxanthin, and fish oil can improve the protective pigment in your eyes. It may help people with low macular pigment and good vision who are not already taking high doses of these nutrients.
College Station, TexasAges 18–45 - NCT06479174Recruiting
Cognitive strategies after stroke with family support
This study tests if combining cognitive exercises with a safe, mild brain stimulation can help improve memory and thinking after a stroke. It also looks at how shared family health history might affect recovery.
Albuquerque, New MexicoAges 18 years+ - NCT06219889Recruiting
Study of Neurocheck effects on thinking after brain bleed
This study looks at how a quick thinking-and-memory check (called a Neurocheck) affects patients recovering from a small, stable brain bleed in the ICU. It helps doctors understand if these checks are helpful for your recovery.
San Diego, CaliforniaAges 18–100 - NCT06470516Recruiting
Brain stimulation for cognitive issues in schizophrenia
This study tests a type of brain stimulation called high-definition transcranial alternating current stimulation (hi-tACS) to see if it can improve thinking and memory in people with schizophrenia. If you are a right-handed adult with stable schizophrenia, you may be able to join.
Hanzhou, ZhejiangAges 18 years+ - NCT06468176Recruiting
Remote program for memory and thinking after brain tumor
This study tests a remote program to help with memory and thinking problems caused by a grade 2 or 3 brain tumor. It is for people who have had surgery and are at least 6 months past any radiation or chemotherapy.
Montpellier, HéraultAges 18 years+ - NCT06472492Recruiting
Yoga for thinking and memory after depression
This study tests whether yoga can help improve thinking and memory in people who have had depression but are now feeling better. You would participate in a yoga program and researchers will see if it helps your cognitive skills.
Bengaluru, KarnatakaAges 18–60 - NCT06467539RecruitingPhase 2
New combination treatment for early Alzheimer's or memory loss
This trial tests a new combination treatment (DAOIB and an antioxidant) for people with early Alzheimer's or mild cognitive impairment. It aims to see if the treatment can help slow or improve memory and thinking problems.
Kaohsiung CityAges 50–90 - NCT03761381Recruiting
Eye scan study for mild Alzheimer’s and memory changes
This study uses detailed eye imaging (an eye scan) to look for signs related to probable Alzheimer’s disease and mild dementia. It may help researchers understand whether eye scans can reflect brain changes and improve detection.
Portland, OregonAges 55 years+ - NCT06458920Recruiting
How friends help teens manage emotions
This study looks at how teens and young adults learn to manage their emotions. If you fit the age range and are healthy enough for an MRI, you may help us understand how social situations affect emotion regulation.
Los Angeles, CaliforniaAges 13–25 - NCT06454344Recruiting
Sleep and childhood experiences study in young adults
This study looks at how sleep is affected by tough childhood experiences. It tests whether changing sleep patterns can help young adults who have had these experiences and currently have poor sleep.
Iowa City, IowaAges 18–29 - NCT06453980Recruiting
Brain plasticity study in mild memory loss
This study looks at how the brain changes in people with mild memory problems. It uses brain scans and a gentle, non-invasive electrical stimulation to see if we can improve brain function.
Ann Arbor, MichiganAges 60 years+ - NCT06458335Recruiting
Treating opioid use and loneliness
This study tests a program to help people with opioid use disorder who also feel lonely. It aims to see if treating both together can improve your health and wellbeing.
Rochester, New YorkAges 18 years+
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Common questions
- Are there clinical trials for cognition?
- Yes. Clin2 currently lists 1,981 recruiting cognition studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognition trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognition trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.