Clinical trials
Cognitive Impairment clinical trials
Below are recruiting cognitive impairment clinical trials, each written for real people, not researchers. We’re tracking 571 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04722939Recruiting
Testing brain function outcomes after ICU kidney failure treatment
This trial studies how treating severe kidney injury in the ICU may affect patients’ brain and thinking function over time. It compares measurements of brain activity and function after starting kidney replacement therapy.
Kingston, OntarioAges 18 years+ - NCT06337201Recruiting
Digital life stories for dementia care
This trial tests a digital tool to create life stories for older adults with dementia. It aims to help healthcare workers provide more personalized care.
Karlskrona, Blekinge CountyAges 18 years+ - NCT06342661Recruiting
VISTA protein in blood vessel-related memory problems
This study measures levels of a protein called VISTA in the blood of people with memory problems caused by blood vessel disease. It aims to see if VISTA can help diagnose or predict this condition.
Harbin, HeilongjiangAges 50–80 - NCT06385951Recruiting
Virtual reality navigation test for early Alzheimer's detection
This study uses a virtual reality navigation task to detect early signs of Alzheimer's disease. It compares people with mild cognitive problems, mild Alzheimer's, and healthy older adults to see if this test can spot the disease earlier.
Ghent, East-FlandersAges 50–80 - NCT07852650RecruitingPhase 1/Phase 2
Fall prevention app study
This study tests a digital program to help older adults reduce their risk of falling. It is designed for people who are generally healthy and can walk on their own, and it may help you feel steadier and safer.
Atlanta, GeorgiaAges 50 years+ - NCT07844850Recruiting
Blood tests to predict silent strokes after heart procedures
This study looks at whether certain blood tests can help predict if small, silent strokes occur in the brain during heart or blood vessel procedures that carry a higher risk of clots. The goal is to better identify who might need extra protection during these procedures.
ThessalonikiAges 18 years+ - NCT07842146Recruiting
Urolithin a for people with alzheimer's disease
This study tests a dietary supplement called Urolithin A (Mitopure®) to see if it helps people with mild-to-moderate Alzheimer's disease. You would take the supplement or a placebo, and researchers will track your memory and daily function over time.
PragueAges 55–85 - NCT06210022Recruiting
Cognitive problems in drug-resistant vs drug-responsive epilepsy
This study compares thinking skills in people with focal epilepsy that responds well to medication versus epilepsy that doesn't. It aims to understand how different types of epilepsy affect memory, attention, and other cognitive functions.
MilanAges 18–60 - NCT06444841Recruiting
Memory aids for mild memory loss
This study tests whether using a paper-based or smartphone-based memory support system helps people with mild memory problems remember daily tasks. You and a family member or friend will both participate.
Austin, TexasAges 50 years+ - NCT07810517Recruiting
Probiotic and fiber supplement for memory in obesity
This study tests a daily supplement (a probiotic called Lactobacillus acidophilus plus a fiber called inulin) to see if it might help improve memory and thinking in adults with long-term obesity and mild cognitive impairment. If you qualify, you would take the supplement or a placebo for a period of time while the study team monitors your cognitive function.
Huixquilucan, State of MexicoAges 30–40 - NCT07799402Recruiting
How gut and brain health change with age
This study looks at how the bacteria in your gut are linked to brain health as you age. It includes people with normal memory, mild memory problems, or Alzheimer's disease, and aims to find ways to keep brains healthy as we get older.
Tampa, FloridaAges 18 years+ - NCT06050603Recruiting
MRI guided brain stimulation study for memory
This study tests a new way to use brain stimulation guided by MRI to understand memory. It may help people with mild memory problems or healthy volunteers.
Toronto, OntarioAges 18–80 - NCT07768579Recruiting
Sequential treatment for Alzheimer's disease
This study tests a sequence of treatments to see if they can help people with Alzheimer's disease or mild cognitive impairment. It aims to slow down memory decline and improve daily function.
Beijing, Beijing MunicipalityAges 55–85 - NCT07758660Enrolling by invitationPhase 2
Brain scan study for Alzheimer's research
This study uses brain scans (PET) to look at changes in the brain that may be related to memory problems or Alzheimer's disease. It aims to improve understanding of the disease and may help develop better treatments.
New York, New YorkAges 50 years+ - NCT05826548Recruiting
Telerehabilitation program for memory, Parkinson’s, and stroke needs
This trial studies a home-based exercise and training program delivered by telerehabilitation (remote care) for people with mild cognitive impairment, Parkinson’s disease, or stroke. It may help improve day-to-day thinking and movement skills by supporting you with structured practice from home.
Lido, VeneziaAges 18–85 - NCT07724132RecruitingPhase 3
Treatments for sustained response in Alzheimer's disease
This study tests whether a treatment (atomoxetine or metformin) can help people with Alzheimer's disease maintain an improved state for at least 18 months. It may help you or a loved one stabilize symptoms and slow disease progression.
CambridgeAges 55 years+ - NCT06363981Recruiting
Brain stimulation for depression, sleep and memory problems
This study tests a non-invasive brain stimulation treatment (called rTMS) to help with depression, sleep problems, and memory or concentration issues. It's designed for people with moderate to severe depression who also have trouble sleeping and thinking clearly.
KrakowAges 18–65 - NCT07701785Recruiting
Brain stimulation study for Parkinson's with mild memory issues
This trial tests a type of brain stimulation called iTBS on an area of the brain that may help with thinking and memory problems in people with Parkinson's disease and mild cognitive impairment. If you qualify, you and your caregiver would take part in sessions and answer questions about your daily life.
Charleston, South CarolinaAges 50–85 - NCT07672977Enrolling by invitation
Sound therapy at home to improve deep sleep in early Alzheimer's
This study tests whether a wearable device that plays soft sounds during sleep can boost deep sleep brain waves in people with mild memory problems caused by Alzheimer's. It aims to see if this simple, home-based approach can help protect memory and thinking.
Zaragoza, ZaragozaAges 50–75 - NCT07667478Recruiting
Brain stimulation study for early Alzheimer's memory loss
This study tests whether a non-invasive magnetic brain stimulation technique can help improve memory in people with early Alzheimer's disease. It may be an option if you have mild cognitive impairment or mild dementia due to Alzheimer's and have had a positive blood test for Alzheimer's markers.
Houston, TexasAges 55–90 - NCT07658287Recruiting
Virtual reality for older adults in long-term care
This trial tests whether using a virtual reality headset can improve wellbeing for older adults living in long-term care homes. It is designed for people with mild to moderate memory or thinking problems who can use the headset safely.
Québec, QuebecAges 60 years+ - NCT07659964Recruiting
Rhythmic music and walking study for Alzheimer's
This study tests whether listening to a steady beat (rhythmic music) while walking can improve movement and brain function in people with mild Alzheimer's disease. Healthy volunteers are also needed for comparison.
Boston, MassachusettsAges 50–90 - NCT06572748Recruiting
Cooking study for older adults with memory concerns
This study tests a cooking program called Chef Anchor 3.0 for older adults with mild memory problems or dementia. It looks at whether learning to cook can help with thinking skills and daily life.
Hong KongAges 60 years+ - NCT07646054Enrolling by invitation
Lifestyle coaching for preventing Alzheimer's in APOE4 carriers
This study tests a digital lifestyle coaching program designed to help prevent Alzheimer's disease in people who carry the APOE4 genetic variant, which increases risk. Over one year, you'll get personalized health coaching through apps and possibly a smart ring to track your progress.
La Jolla, CaliforniaAges 60–80
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Common questions
- Are there clinical trials for cognitive impairment?
- Yes. Clin2 currently lists 571 recruiting cognitive impairment studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive impairment trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive impairment trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.