Clinical trials
Cognitive Dysfunction, Cognitive Disorder clinical trials
Below are recruiting cognitive dysfunction, cognitive disorder clinical trials, each written for real people, not researchers. We’re tracking 122 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05201534Recruiting
Math and thinking skills training for school-age children
This trial studies interventions to improve math and cognitive (thinking) skills in elementary school children. It includes both children with math learning difficulties and typically developing children, using tests and MRI brain scans for those who can participate.
Palo Alto, CaliforniaAges 6–12 - NCT07736885Recruiting
Hand stimulation for thinking problems after stroke
This study tests a gentle, painless electrical stimulation on specific points on the hands to see if it helps improve thinking and memory after a stroke. It is for people who have had a stroke in the last 2 weeks to 6 months and are noticing some cognitive changes.
Tianjin, Tianjin MunicipalityAges 35–80 - NCT07719712Recruiting
Thinking and confusion after prostate surgery in older adults
This study looks at how older adults' thinking and memory may change after a common prostate surgery, and whether some patients become confused or delirious afterward. It may help doctors understand who is at risk for these problems.
MuğlaAges 65 years+ - NCT03360838Recruiting
Prediction test for confusion after heart surgery in older adults
This study uses a short, self-answered thinking test before elective heart surgery to help predict who may develop confusion afterward. The goal is to improve early identification and care planning for patients at higher risk.
BaselAges 60 years+ - NCT04289142RecruitingPhase 4
Testing memory effects of dexmedetomidine during heart surgery
This study looks at how a sleep medicine called dexmedetomidine affects thinking and memory after heart surgery. It compares cognitive outcomes over time to see if this sedation choice changes long-term brain function.
Vancouver, British ColumbiaAges 60 years+ - NCT04493996Recruiting
Cognitive training before heart surgery to protect memory
This trial tests whether brain-focused cognitive training before elective heart surgery can help reduce memory and thinking problems afterward. If you qualify, you may do language-based thinking exercises and complete short brain tests around the time of surgery.
Bad NauheimAges 18 years+ - NCT05245903Recruiting
Test a supplement and track brain changes with wearable sensors
This study tests whether taking nicotinamide riboside (a form of niacin) affects early memory changes in people with mild cognitive impairment (MCI) or mild Alzheimer’s disease (AD). It also uses passive wearable or sensor data (“digital biomarkers”) to measure changes over time.
Belmont, MassachusettsAges 18–89 - NCT05273125Recruiting
Testing mobility and thinking in people with mild cognitive problems
This study looks at how well people with mild cognitive problems can think and move, using brief learning/thinking tests and a walking task. It may help researchers understand changes early enough to guide future care.
LilleAges 65 years+ - NCT06546917Recruiting
Cognitive training trial for mild depression with brain scans
This trial tests a computer-based cognitive training program (bWell-D) to see if it can improve thinking skills like memory and focus in people with mild depression. You will also have an MRI brain scan to see how the training affects your brain.
Vancouver, British ColumbiaAges 19–55 - NCT06728774Recruiting
Cognitive rehab for veterans with depression and memory problems
This trial tests a cognitive rehabilitation program for veterans who have depression (MDD) and are experiencing trouble with memory, attention, or thinking. The goal is to see if the program can improve these cognitive issues.
Portland, OregonAges 18 years+ - NCT06853405Recruiting
Nutrition program to prevent memory decline
This study tests whether nutrition-based changes can help prevent memory loss and thinking problems in people who are at higher risk for dementia. To join, you need to be between 55 and 85, have at least 4 years of schooling, and have an elevated dementia risk score.
Porto, PortugalAges 55–85 - NCT06936397Recruiting
Cognitive therapy for schizophrenia: Brain changes and emotions
This trial tests a cognitive training program for people with schizophrenia to see if it improves thinking and emotional control, and how it affects brain activity measured by EEG.
IstanbulAges 18–55 - NCT06951919Recruiting
HOBSCOTCH study for memory help in MS
This trial tests a program called HOBSCOTCH to help people with MS who have memory or thinking problems. It also includes a caregiver who supports them.
Lebanon, New HampshireAges 20–75 - NCT07182396Recruiting
Video games vs ball tossing for hand-eye coordination in older adults
This study tests whether playing video games or tossing balls can improve hand-eye coordination in older adults with mild memory problems. It is designed for people 60 and older who have mild cognitive impairment but are otherwise independent.
IslamabadAges 60 years+ - NCT07242495Recruiting
Virtual reality with exercise for memory in older adults
This trial tests whether using 360-degree virtual reality videos during aerobic exercise can improve thinking and memory in older adults with mild cognitive impairment. It's a chance to try a new approach that combines exercise and immersive technology.
IslamabadAges 60 years+ - NCT07304674Recruiting
Primary Aldosteronism and Thinking Ability Study
This study looks at whether primary aldosteronism (a treatable cause of high blood pressure) is linked to memory and thinking problems. It may help understand if managing this condition can protect brain health.
Chengdu, SichuanAges 40 years+ - NCT07526740Recruiting
Brain Stimulation and Training for Mild Memory Loss
This study tests whether combining brain stimulation (TMS) with cognitive training games can help people with mild cognitive impairment—early memory and thinking problems. The goal is to see if this combination improves thinking abilities and slows cognitive decline.
Charleston, South CarolinaAges 60–85 - NCT07586501Enrolling by invitation
Brain Health and Immune System Study in Older Adults
This research study examines how the brain's immune system changes in older adults with memory problems, Parkinson's disease, or normal aging. By understanding these changes, researchers hope to better understand neurodegeneration and develop new treatments.
Yantai, ShandongAges 55–75 - NCT07000500Enrolling by invitation
Nutritional supplement for memory decline in older adults
This trial tests whether a nutritional supplement can help slow or improve memory loss in older adults who have mild cognitive decline (noticeable changes in thinking skills that are not yet dementia). You will take a daily supplement and attend regular check-ups.
Vila Nova de Famalicão, Braga DistrictAges 65 years+ - NCT04610697Recruiting
Cognitive training for people in forensic mental health care
This trial studies whether a structured “cognitive remediation” program (training thinking skills) can help people receiving care on a forensic treatment unit. It may benefit those who want support improving attention, memory, or problem-solving as part of their treatment.
Ottawa, OntarioAges 18–55 - NCT05616559Recruiting
Precision-guided treatment for single-episode depression
This study tests a more personalized approach to treating depression in people who have had one episode. It uses questionnaires and brain scans (for some participants) to help decide which treatment approach may work best.
CopenhagenAges 18–65 - NCT06579677Recruiting
Watching small blood vessels in the brain over time
This study watches how small blood vessels in the brain change over time. It may help doctors understand brain health as people age.
Beijing, Beijing MunicipalityAges 50–75 - NCT06930846Recruiting
Brain cancer cognitive training study
This study tests a home-based program called HOBSCOTCH-CA to help with memory and thinking problems after brain cancer treatment. The program uses phone and internet sessions to teach self-management skills.
Lebanon, New HampshireAges 18 years+ - NCT05565833RecruitingPhase 2
Online sleep program for insomnia and thinking problems
This Phase 2 study tests an internet-based sleep program to help older adults with insomnia and related thinking difficulties. It may help improve sleep and reduce how much tiredness and sleep disruption affect daily life.
Charlottesville, VirginiaAges 65 years+
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Common questions
- Are there clinical trials for cognitive dysfunction, cognitive disorder?
- Yes. Clin2 currently lists 122 recruiting cognitive dysfunction, cognitive disorder studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cognitive dysfunction, cognitive disorder trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cognitive dysfunction, cognitive disorder trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.