Clinical trials
Colitis clinical trials
Below are recruiting colitis clinical trials, each written for real people, not researchers. We’re tracking 308 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05663775RecruitingPhase 2
Mesalamine to prevent bowel inflammation after melanoma immunotherapy
This study tests whether taking mesalamine can prevent colitis (bowel inflammation) in people with advanced melanoma who are treated with ipilimumab plus nivolumab. It may help reduce dangerous stomach or bowel side effects from this cancer treatment.
Edmonton, AlbertaAges 18 years+ - NCT06538402Recruiting
Comparing two J-pouch sizes in pouch surgery
This trial compares two different J-pouch sizes (10 cm vs. 15 cm) during surgery for ulcerative colitis or FAP. The goal is to see if one size leads to better outcomes.
AarhusAges 18–60 - NCT06844318Recruiting
IBD treatment and frailty in patients over 60
This study looks at how inflammatory bowel disease (IBD) activity affects frailty in people over 60. It tests whether starting or changing medication for active IBD can help understand and manage frailty.
Vitoria-Gasteiz, AlavaAges 60 years+ - NCT06810518Recruiting
Studying stool test for digestive disease diagnosis
This trial tests a new stool test to measure calprotectin levels, which could help doctors tell the difference between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). If you have symptoms like stomach pain, diarrhea, or weight loss and are about to have a colonoscopy, you may be able to join.
Miami, FloridaAges 22 years+ - NCT06807593RecruitingPhase 2
Treating ICI-related diarrhea or colitis with ustekinumab
This trial tests if ustekinumab can help cancer patients who have diarrhea or colitis caused by immune checkpoint inhibitors. It may be an option if standard treatments haven't worked or aren't suitable.
Houston, TexasAges 18 years+ - NCT06805890Recruiting
Tissue repair study in IBD using organoid technology
This study collects tissue samples from people with Crohn's disease or ulcerative colitis during routine colonoscopy or surgery to grow mini-organs (organoids) in the lab. The goal is to learn how the gut heals itself, which could lead to better treatments.
MarseilleAges 18 years+ - NCT06750731Recruiting
IV vs. shot vedolizumab for IBD with remote check-ins
This study compares two ways of taking the IBD medicine vedolizumab (injecting under the skin versus through an IV line). You'll use a smartphone app to report your symptoms, so you can participate from home and help doctors learn which option works better.
New Orleans, LouisianaAges 18 years+ - NCT06754891RecruitingPhase 1
A study of TQH3906 for moderate to severe inflammatory bowel disease
This trial tests a new medicine (TQH3906) for people with moderate to severe ulcerative colitis or Crohn's disease that hasn't improved with other treatments. The goal is to see if it can help control inflammation in the gut.
Bengbu, AnhuiAges 18–75 - NCT06742385Recruiting
Smartphone app to monitor active inflammatory bowel disease
This study tests a smartphone app (SEMEIA) to help monitor people with active Crohn's disease or ulcerative colitis. It may help you track your symptoms and stay in touch with your doctor without needing as many office visits.
Neuilly-sur-Seine, FranceAges 18–80 - NCT06722456Enrolling by invitation
Better ways to detect active IBD
This study tests non-invasive tools to find active inflammation in people with Crohn's disease or ulcerative colitis. You may need to give extra stool samples before your colonoscopy and calprotectin test.
Sherbrooke, QuebecAges 18 years+ - NCT06696222Recruiting
Fermented vegan diet for health and colitis
This trial tests whether a fermented vegan diet can improve health in people with inflammatory bowel disease (IBD), like ulcerative colitis or Crohn's disease, and in healthy volunteers. It aims to see how the diet affects the gut.
MalmöAges 18 years+ - NCT06663332RecruitingPhase 3
Long-term study of guselkumab in children who previously took it
This study is a long-term follow-up for children who have already finished an earlier study of guselkumab, a medicine for skin conditions like psoriasis. It looks at whether staying on the medicine continues to be safe and helpful over time.
Atlanta, GeorgiaAges 3 years+ - NCT04330846Recruiting
Study of new narrowing in Crohn’s treated with two approaches
This study looks at treatments for a new (de novo) narrow area in the bowel from Crohn’s disease. It aims to see which treatment works better at relieving blockage-type symptoms for the safest, most effective option.
Badalona, BarcelonaAges 18–80 - NCT06581042Recruiting
Study of upadacitinib in adults with IBD in Belgium
This study looks at how adults with Crohn's disease or ulcerative colitis are doing after taking upadacitinib (Rinvoq) for at least 12 months. It helps doctors understand treatment patterns and outcomes in real-world settings.
Bonheiden, AntwerpenAges 18 years+ - NCT06583395Enrolling by invitation
Meditation retreat study with fitness tracker
This trial studies people attending a 7-day meditation retreat to see how meditation affects well-being. You will wear a fitness tracker and answer surveys.
Palm Desert, CaliforniaAges 21 years+ - NCT06571669Recruiting
Nerve stimulation device for ulcerative colitis
This trial tests a new medical device called BOOM-IBD2 that uses gentle nerve stimulation to treat ulcerative colitis. It's for people who have not had UC surgery and do not have certain infections or other implanted devices.
Folsom, CaliforniaAges 18–85 - NCT06579443Recruiting
Robotic surgery study for inflammatory bowel disease
This study looks at how well robotic surgery works for people with inflammatory bowel disease. It aims to help surgeons learn and improve outcomes for patients like you.
Coventry, West MidlandsAges 18 years+ - NCT06550310Recruiting
Nutrition and IBD treatment outcomes
This study looks at how nutrition affects people with IBD who are starting a new treatment or having surgery. Researchers want to find out if diet or body changes influence how well you recover.
LondonAges 16 years+ - NCT06560021Enrolling by invitation
Random biopsies in inflammatory bowel disease surveillance
This trial looks at whether taking random biopsies during a routine colonoscopy is helpful for people with inflammatory bowel disease (IBD) who are at risk for colon cancer. It aims to understand if random biopsies can detect early signs of cancer or pre-cancer.
Birmingham, AlabamaAges 18 years+ - NCT06548399Recruiting
Bacteria study for IBD patients with ongoing abdominal pain
This study looks at bacteria in your gut that may produce chemicals linked to ongoing pain in Crohn's disease or ulcerative colitis, even when the disease itself is not very active. Researchers want to understand why some people still have moderate to severe abdominal pain even after their inflammation has calmed down.
Hamilton, OntarioAges 18–70 - NCT02523118Recruiting
Measuring symptoms and test results in eosinophilic gut diseases
This study looks at how eosinophilic inflammation in the esophagus and intestines affects outcomes like symptoms and test findings. It may help clinicians better understand these conditions and track what changes over time.
Phoenix, ArizonaAges 3 years+ - NCT06246123Recruiting
Jyseleca tablet safety study in Korean patients
This study tracks Korean patients already taking Jyseleca for rheumatoid arthritis or ulcerative colitis, making sure it's safe and working as expected. It's not testing a new drug, just watching how patients do over time.
Cheonan, Chungcheongnam-doAges 18 years+ - NCT06088537Recruiting
Blood in newborn stool: allergy or temporary colitis?
This study looks at very young babies (less than a month old) who have blood in their stool but are otherwise well. The goal is to find out whether the bleeding is due to a food allergy or a short-term gut irritation, so doctors can give the right care.
Nice, Alpes-MritimesAges 1 day–4 weeks - NCT06065228Recruiting
Tracking treatment progress in children with IBD
This study looks at a new way to measure how well treatment is working in children with inflammatory bowel disease (IBD). It uses a special eye test called pupillometry, which is painless and non-invasive, to see if it can help doctors adjust treatment earlier.
Washington D.C., District of ColumbiaAges 6–21
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Common questions
- Are there clinical trials for colitis?
- Yes. Clin2 currently lists 308 recruiting colitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.