Clinical trials
Colitis clinical trials
Below are recruiting colitis clinical trials, each written for real people, not researchers. We’re tracking 321 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06750731Recruiting
IV vs. shot vedolizumab for IBD with remote check-ins
This study compares two ways of taking the IBD medicine vedolizumab (injecting under the skin versus through an IV line). You'll use a smartphone app to report your symptoms, so you can participate from home and help doctors learn which option works better.
New Orleans, LouisianaAges 18 years+ - NCT06754891RecruitingPhase 1
A study of TQH3906 for moderate to severe inflammatory bowel disease
This trial tests a new medicine (TQH3906) for people with moderate to severe ulcerative colitis or Crohn's disease that hasn't improved with other treatments. The goal is to see if it can help control inflammation in the gut.
Bengbu, AnhuiAges 18–75 - NCT06756100Recruiting
Early inflammatory bowel disease study
This trial looks at early signs of inflammatory bowel disease (IBD) in adults who have had stomach or bowel symptoms for at least 3 weeks. It aims to understand how the disease progresses.
SantiagoAges 18–100 - NCT06758024Recruiting
Optimizing infliximab for inflammatory bowel disease
This trial tests whether closely monitoring and adjusting infliximab (a biologic medicine) can help people hospitalized with a moderate-to-severe flare of Crohn's disease, ulcerative colitis, or unclassified inflammatory bowel disease who haven't gotten better with IV steroids. The goal is to improve treatment response and outcomes.
SantiagoAges 18–75 - NCT06780683Recruiting
Testing upadacitinib for inflammatory bowel disease
This study tests a medication called upadacitinib for people with inflammatory bowel disease (ulcerative colitis or Crohn's). The goal is to see how well it works and if it's safe.
Guangzhou, GuangdongAges Any age - NCT06802887Recruiting
Long-term study of ustekinumab for Crohn's and colitis
This study follows patients with Crohn's disease or ulcerative colitis who started taking ustekinumab between February 2019 and March 2021, to see how well it works over time.
Bologna, BolognaAges 18 years+ - NCT06805890Recruiting
Tissue repair study in IBD using organoid technology
This study collects tissue samples from people with Crohn's disease or ulcerative colitis during routine colonoscopy or surgery to grow mini-organs (organoids) in the lab. The goal is to learn how the gut heals itself, which could lead to better treatments.
MarseilleAges 18 years+ - NCT06807593RecruitingPhase 2
Treating ICI-related diarrhea or colitis with ustekinumab
This trial tests if ustekinumab can help cancer patients who have diarrhea or colitis caused by immune checkpoint inhibitors. It may be an option if standard treatments haven't worked or aren't suitable.
Houston, TexasAges 18 years+ - NCT06810518Recruiting
Studying stool test for digestive disease diagnosis
This trial tests a new stool test to measure calprotectin levels, which could help doctors tell the difference between inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS). If you have symptoms like stomach pain, diarrhea, or weight loss and are about to have a colonoscopy, you may be able to join.
Miami, FloridaAges 22 years+ - NCT06862843Recruiting
Family eating habits and chronic inflammation study
This study looks at how eating habits and family health history relate to chronic inflammatory conditions like Crohn's disease, ulcerative colitis, and juvenile idiopathic arthritis. It aims to understand these links by studying families with a child or adult affected by these conditions, as well as healthy families.
Florence, ItalyAges Any age - NCT06892990Recruiting
Better imaging for inflammation in bowel disease
This trial tests a new imaging technique that may help doctors see inflammation more clearly during colonoscopy in people with Crohn's disease or ulcerative colitis. The technique is called Texture and Color Enhancement Imaging (TXI).
Ulm, Baden-WurttembergAges 18 years+ - NCT06954311Recruiting
Drug monitoring for children with IBD
This study monitors levels of certain medications (infliximab, adalimumab, vedolizumab, ustekinumab) in children with inflammatory bowel disease to see if adjusting the dose helps them feel better. It aims to improve treatment outcomes.
FeldkirchAges birth–18 years - NCT06995170Recruiting
Polyamines and IBD progression study
This study looks at how certain natural chemicals called polyamines relate to the activity of inflammatory bowel disease (IBD). It aims to understand if these chemicals can help predict disease progression.
Xi'an, ShaanxiAges 18–65 - NCT07013578Recruiting
Mental health support trial for IBD patients
This trial tests a mental health program for people with inflammatory bowel disease (IBD) who have mild to moderate anxiety or depression. It aims to see if the program can improve their emotional well-being.
North York, OntarioAges 18–75 - NCT07046468Recruiting
Smart pill to check gut health in colon inflammation and cancer
This trial tests a smart pill that measures gut health in people with colon inflammation (ulcerative colitis) or colon cancer. It aims to see if the pill can help doctors better understand how the gut is working during treatment or before surgery.
Nijmegen, GelderlandAges 18 years+ - NCT07102368Recruiting
Study of guselkumab for inflammatory bowel disease in Germany
This study tracks how well guselkumab (Tremfya) works in real-life for people with inflammatory bowel disease in Germany. If you are starting this treatment, researchers will watch your progress and ask you to fill out simple surveys about your symptoms.
BerlinAges 18 years+ - NCT07113522RecruitingPhase 2
Study of new therapies for Crohn's and colitis
This trial tests new therapies for people with moderate to severe Crohn's disease or ulcerative colitis. It may help if your standard treatments aren't working well enough.
Birmingham, AlabamaAges 18–80 - NCT07132333Recruiting
Personalized inflammation study for chronic conditions
This study uses advanced testing to understand inflammation in people with certain chronic inflammatory diseases, such as psoriasis, psoriatic arthritis, other types of arthritis, or inflammatory bowel disease. The goal is to tailor treatment to your specific needs.
TübingenAges 18 years+ - NCT07141238Recruiting
Microplastics in kids with inflammatory bowel disease
This study looks at whether tiny plastic particles (called microplastics) are found in the guts of children with and without inflammatory bowel disease. By analyzing samples taken during a routine endoscopy, researchers hope to learn if these particles might play a role in the disease.
GdanskAges Up to 18 years - NCT07168499Recruiting
Diet, stress, and advanced therapy for Crohn's and colitis
This study tests whether adding a diet and stress management program to standard advanced therapy helps people with active Crohn's disease or ulcerative colitis feel better. It combines lifestyle changes with new medications to improve treatment outcomes.
Boston, MassachusettsAges 18 years+ - NCT07191106Recruiting
Remote exercise program for inflammatory bowel disease
This study tests whether a remote exercise program, done at home using an app, can improve quality of life for people with inflammatory bowel disease (IBD). It may help if you are motivated to start a gentle physical activity routine and have internet access.
MontfermeilAges 18 years+ - NCT07198113Recruiting
Comparing newer treatments for pediatric inflammatory bowel disease
This study is for children and teens with inflammatory bowel disease (Crohn's, colitis, or indeterminate) whose previous anti-TNF medicine stopped working. It compares several newer treatments to see which works best.
Chapel Hill, North CarolinaAges 1–18 - NCT07216014RecruitingPhase 4
IL-23 antibody for inflammatory bowel disease
This trial tests a new antibody drug (IL-23 inhibitor) for people with Crohn's disease or ulcerative colitis. It aims to see if the drug is safe and effective. You may be able to join if you have moderate to severe disease and have not had certain bowel surgeries or infections.
Guangzhou, GuangdongAges 18–65 - NCT07223424RecruitingPhase 2
Patient preference study: shot vs infusion for immunotherapy
This study compares two ways to take immunotherapy drugs (nivolumab or pembrolizumab): as a shot under the skin (subcutaneous) versus an infusion into a vein (intravenous). It looks at which method patients prefer and is for people with certain advanced cancers where these drugs are already approved.
Pittsburgh, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for colitis?
- Yes. Clin2 currently lists 321 recruiting colitis studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colitis trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colitis trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.