Clinical trials
Colon Cancer clinical trials
Below are recruiting colon cancer clinical trials, each written for real people, not researchers. We’re tracking 290 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07132970Recruiting
Leakage rate of sutured bowel connection after right colon removal
This trial is testing how well hand-sewn or partially stitched connections (anastomoses) hold up after right colon removal for cancer. It may help improve surgical techniques for people undergoing this operation.
Göppingen, Baden-WurttembergAges 18 years+ - NCT07060443RecruitingPhase 2
Fluorescent dye study for right-sided colon cancer surgery
This trial tests whether using a fluorescent dye during surgery can help doctors better see and remove lymph nodes in people with right-sided colon cancer. It aims to make surgery more precise and potentially improve outcomes.
DaeguAges 19–85 - NCT06989814Recruiting
Liquid biopsy test for Lynch syndrome cancer patients
This trial tests a simple blood test to measure tumor DNA in people with Lynch syndrome who have been newly diagnosed with cancer but haven't started treatment yet. It aims to see if this test can help monitor the cancer.
Leiden, South HollandAges 18 years+ - NCT06931808Enrolling by invitationPhase 4
Fecal transplant with chemo, radiation, and immunotherapy for advanced colon cancer
This study tests a combination of fecal microbiota transplant, chemotherapy, radiation, and immunotherapy (sintilimab) for people with locally advanced rectal cancer. The goal is to see if this approach improves treatment outcomes.
Ningbo, ZhejiangAges 18–75 - NCT06917963Recruiting
Preventing high stoma output with omeprazole
This trial tests if a stronger dose of omeprazole can help prevent high fluid output from a new ileostomy (a surgically created opening in the belly that passes waste). If you are scheduled for surgery to create an ileostomy, you may be able to join.
Gdansk, Pomeranian VoivodeshipAges 18 years+ - NCT06906952Enrolling by invitation
Robotic surgery through the anus vs. standard robotic surgery for rectal cancer
This trial compares two robotic surgery methods for high rectal and sigmoid colon cancer—one that removes the tumor through the anus (NOSES-IV) and the traditional assisted approach. It aims to see which way may lead to better recovery.
NanchangAges 18–80 - NCT05789433Recruiting
Aerobic exercise study after colon or rectal cancer surgery
This trial studies whether a supervised aerobic exercise program helps muscles “remodel” (change/strengthen) after colon or rectal cancer treatment. It may help people improve physical function during recovery, but you can only join if it’s safe for you and you can follow the study plan.
Orlando, FloridaAges 18 years+ - NCT06560671Recruiting
App vs. paper for colonoscopy prep education
This study compares a new smartphone app to standard paper instructions for helping patients get their bowel ready for colonoscopy. It aims to see which method is easier to understand and leads to a better exam.
HsinchuAges 18 years+ - NCT06197425RecruitingPhase 3
Extra chemotherapy after surgery for colorectal cancer with positive ctDNA
This trial tests whether giving more chemotherapy can help people who still have cancer DNA in their blood after surgery and standard chemotherapy for colorectal cancer. The goal is to prevent the cancer from coming back.
DijonAges 18–80 - NCT05884723Recruiting
Ketogenic diet before liver surgery for fatty liver
This trial tests whether a ketogenic (very low-carb) diet before liver surgery can reduce fat in the liver. It is aimed at people with colorectal liver metastases who already have fatty liver seen on scans or biopsy.
London, OntarioAges 18 years+ - NCT05672108RecruitingPhase 2
Chemo delivered into lung tumors using a catheter
This trial studies a treatment that delivers chemotherapy directly to lung tumors by placing a catheter into lung blood vessels. It may help people with lung cancer or lung metastases that are growing despite standard treatment, or who cannot tolerate it.
Duarte, CaliforniaAges 18 years+ - NCT05561504Recruiting
Study of stomach bacteria resistance in adults
This study looks at how common a stomach bacteria infection is and which antibiotics still work. You may help researchers by providing consent for related study participation and sample tracking.
MunichAges 18 years+ - NCT07541924Recruiting
Image-Guided Colonoscopy: Patient Experience and Doctor Efficiency
This study tests whether using CT scan images to guide doctors during colonoscopy (a camera exam of your colon) improves how well the procedure goes and reduces doctor stress. You'll answer questions about your experience before and after the procedure.
Beijing, Beijing MunicipalityAges 18–80 - NCT06287671Recruiting
Colorectal Surgery Tissue Study for Better Understanding of Disease
This study is collecting tissue samples from people having surgery on their colon or rectum to better understand colorectal diseases. It may help researchers learn more about conditions like cancer, polyps, or inflammatory bowel disease.
HillerødAges 18 years+ - NCT04624555Recruiting
Check how well stool DNA tests help watch for colon cancer return
This trial studies whether an at-home stool DNA test (Mt-sDNA) can safely and usefully monitor people after colon or rectal cancer treatment. It’s mainly about whether the test is practical and helpful during routine follow-up.
Cleveland, OhioAges 18 years+ - NCT07811193RecruitingPhase 2
Study of new drug combined with immunotherapy for advanced bowel cancer
This trial tests a new drug (VVD-133214) combined with an existing immunotherapy (pembrolizumab) for advanced colorectal cancer that is mismatch repair deficient. It aims to see if the combination works better than pembrolizumab alone in shrinking or controlling the cancer.
Tucson, ArizonaAges 18 years+ - NCT07573371Recruiting
Understanding bowel changes after rectal cancer surgery
This study helps doctors better understand and treat bowel control problems that can happen after rectal cancer surgery or other rectal treatments. If you've had this surgery or treatment, the study team wants to learn more about your recovery and test new ways to help.
AalborgAges 18 years+ - NCT07419490Recruiting
Moving ovaries and uterus to preserve fertility during pelvic radiation
This trial moves the ovaries and uterus higher in the belly before pelvic radiation to protect them, so patients may still be able to have children later. It is for women aged 18-40 with pelvic cancers that require radiation.
Tampa, FloridaAges 1.5 years–3.3 years - NCT07154173Recruiting
Gut bacteria study in metastatic colorectal cancer
This study looks at gut bacteria in people with colorectal cancer that has spread (metastatic). It aims to find patterns in the bacteria that may help doctors choose better treatments.
Guangzhou, GuangdongAges 18–75 - NCT06807073Recruiting
Closing the wound after large colon polyp removal
This study compares closing the wound after removing a large colon polyp to leaving it open. The goal is to see if closing the area reduces bleeding or other problems.
Montreal, QuebecAges 18 years+ - NCT06272461Recruiting
Comparing lidocaine vs. ketamine for colorectal surgery pain
This trial compares two pain-relief medicines (lidocaine vs. ketamine) given through an IV during open colorectal surgery. It aims to find which one works better to reduce pain after surgery.
NabeulAges 18–90 - NCT06271941Recruiting
Reducing polyp return after large colon polyp removal
This trial is testing a standard way to remove large polyps from the colon and checking if it helps prevent them from coming back. It's for people who have a large non-cancerous polyp that needs to be taken out during a colonoscopy.
Montreal, QuebecAges 18 years+ - NCT06381882Enrolling by invitation
Human microbiome study after pancreatic surgery
This study looks at how tiny organisms in your gut (the microbiome) affect recovery after surgery for pancreatic cancer or related growths. It may help doctors understand how to improve outcomes for future patients.
NieuwegeinAges 18 years+ - NCT06957015Recruiting
New system to measure polyp size during colonoscopy
This trial tests a new computer system that helps doctors estimate the size of polyps during a colonoscopy. It may help doctors make better decisions about your treatment.
ShatinAges 18 years+
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Common questions
- Are there clinical trials for colon cancer?
- Yes. Clin2 currently lists 290 recruiting colon cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colon cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colon cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Stand Up To CancerPeople facing cancer across many types, through the research that leads to better treatments.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.