Clinical trials
Colon Cancer clinical trials
Below are recruiting colon cancer clinical trials, each written for real people, not researchers. We’re tracking 290 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05686499Recruiting
Colonoscopy training for early colorectal cancer detection
This trial supports training for healthcare professionals to improve screening and early diagnosis of colorectal cancer. It may help by building skills in safely performing colonoscopies and spotting cancer earlier.
Ile-Ife, Osun StateAges 18 years+ - NCT06731894RecruitingPhase 2
Cannabis for nerve pain after chemotherapy in breast and colon cancer survivors
This trial tests whether a cannabis-based product can reduce nerve damage (neuropathy) caused by chemotherapy in people who have finished treatment for breast or colon cancer. It focuses on survivors who still have pain, numbness, or tingling in their hands or feet.
Duarte, CaliforniaAges 18 years+ - NCT06244537Recruiting
MR-Linac radiation for advanced colon cancer
This trial tests a new radiation machine called MR-Linac for people with advanced colon cancer that cannot be removed by surgery. The goal is to see if it is safe and works well.
Chengdu, SichuanAges 18 years+ - NCT06314022Recruiting
Mobile app for better colonoscopy in cancer screening
This study tests a mobile app designed to help improve the quality of colonoscopies for people in a colorectal cancer screening program. If you have had a positive FIT test and are between 50 and 69, you may be able to join.
Valladolid, ValladolidAges 50–74 - NCT07289568Enrolling by invitation
Comparing surgery types for splenic flexure cancer
This study looks at two types of surgery for cancer in a part of the colon called the splenic flexure. It compares removing just the affected section (segmental colectomy) with removing a larger portion (extended hemicolectomy) to see which has better outcomes.
Istanbul, IstanbulAges 18–80 - NCT07285356Recruiting
Surgical gloves to prevent nerve damage from oxaliplatin
This trial tests whether wearing special surgical gloves during oxaliplatin chemotherapy can help prevent nerve damage (numbness or tingling) in people with advanced colon cancer.
São Paulo, São PauloAges 18 years+ - NCT07462650RecruitingPhase 1/Phase 2
CAR-NK cell therapy for advanced colorectal cancer
This trial tests a new treatment using modified natural killer cells (CAR-NK) that target two specific proteins found on your cancer cells. It is for people with advanced colorectal cancer who have tried standard treatments without success.
Shenzhen, GuangdongAges 18–75 - NCT05706779RecruitingPhase 2
Encorafenib plus cetuximab before surgery for BRAF-mutated colon cancer
This trial tests whether giving encorafenib and cetuximab before surgery can shrink or control BRAF-mutated colon or upper rectal cancer and make surgery more effective. It also checks whether this approach is safe and helps patients do better overall.
ParisAges 18 years+ - NCT05174169RecruitingPhase 2/Phase 3
Adjuvant colon chemotherapy guided by tumor DNA results
This trial tests whether treatment for colon cancer after surgery can be guided by a blood test that looks for leftover cancer signals (ctDNA). It may help some people choose stronger or different chemo based on whether ctDNA is found after surgery.
Birmingham, AlabamaAges 18 years+ - NCT07116668Enrolling by invitation
Colovac device study for colon surgery patients
This trial tests a device called Colovac that protects the connection made during colon surgery for cancer. It may help patients who need a temporary colostomy bag heal better.
Los Angeles, CaliforniaAges 22 years+ - NCT05064124Recruiting
Real-time healthcare system during colonoscopy for colon cancer
This study tests a new real-time healthcare system meant to improve how doctors find and monitor colon cancer risk during colonoscopy. You might be able to take part if you are scheduled for a non-emergency colonoscopy and meet other safety and medical criteria.
LondonAges 18 years+ - NCT07610798RecruitingPhase 1/Phase 2
Testing INV-8989 for Advanced Cancers With KRAS G12D Mutation
This early-stage trial tests a new drug called INV-8989 designed to target a specific genetic mutation (KRAS G12D) found in some advanced solid cancers. The study will evaluate whether the drug is safe and if it can help shrink tumors in patients who haven't responded to standard treatments.
Guangzhou, GuangdongAges 18 years+ - NCT07168876Recruiting
A blood test to screen for colon cancer
This trial studies a new blood test that looks for specific markers of colon cancer. If it works well, it could offer an easier way to screen for the disease without a colonoscopy.
Mendoza, Mendoza ProvinceAges 45–75 - NCT06917794Enrolling by invitation
Genetic risk study for colon cancer patients
This study looks at how your genetic background and ancestry affect your risk for colon cancer. If you have been diagnosed with colon cancer and have a tumor sample available, you may be able to help researchers develop better risk scores.
Fortaleza, CearáAges 18 years+ - NCT05734300Recruiting
Surgery study for older adults with early colon cancer
This study looks at how well a planned surgery approach works for people age 75 and older with early-stage colon cancer. It may help improve outcomes by selecting the right patients for a specific colon operation plan.
Copenhagen, HerlevAges 65 years+ - NCT05495048Recruiting
Transvaginal surgery vs standard laparoscopy for right colon removal
This study compares two surgical approaches for removing the right side of the colon in certain women with colon cancer or a high-risk pre-cancer. It aims to see whether the less invasive transvaginal approach can be done safely and work as well as standard laparoscopic surgery.
ShanghaiAges 18–75 - NCT06126419Recruiting
High-dose insulin for liver function after surgery
This trial tests if high-dose insulin can help your liver work better and heal faster after a major liver surgery for colorectal cancer that has spread to the liver.
Montreal, QuebecAges 18 years+ - NCT04798898Recruiting
RFA plus immune stimulation during liver surgery for colon cancer spread
This trial looks at whether using a heat-based treatment (RFA) to trigger the immune system before or during liver surgery can improve outcomes for people with colon cancer that has spread to the liver. It’s aimed at people who plan to have the liver tumors removed because they look treatable.
AarhusAges 18–99 - NCT07546565Recruiting
Bowel Prep Before Minimally Invasive Colon Cancer Surgery
This trial tests whether cleaning out your colon before surgery for early-stage colon cancer affects outcomes when surgeons use a minimally invasive (laparoscopic) approach. Researchers want to see if this prep step makes a difference in recovery and complications.
Ho Chi Minh City, Ho Chi MinhAges 18 years+ - NCT07431892Recruiting
Pain after robotic vs. laparoscopic colon cancer surgery
This study compares pain levels after two types of minimally invasive colon cancer surgery: robotic and laparoscopic. It aims to see if one approach leads to less pain, which may help you recover more comfortably.
MadridAges 18 years+ - NCT07347158Enrolling by invitation
Health education for ostomy patients
This study teaches people with an ostomy (a surgical opening for waste) about their health to improve their quality of life and reduce anxiety or depression. If you are an adult with a permanent or long-term ostomy and live in the Santiago or Barbanza area, you may be able to join.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT04701853Recruiting
Exercise training after permanent stoma surgery
This trial looks at a specific exercise program after planned surgery to create a permanent stoma (an opening for stool). The goal is to see whether the training helps people recover and function better after surgery.
GothenburgAges Any age - NCT07230639RecruitingPhase 2
Shorter radiation with chemo and immunotherapy for high-risk colon cancer
This trial tests a shorter course of radiation combined with chemotherapy and an immunotherapy drug (PD-1 inhibitor) for people with a specific type of high-risk colon cancer that has not spread. The goal is to see if this approach can shrink the tumor before surgery and improve outcomes.
Guangzhou, GuangdongAges 18–75 - NCT06962293Recruiting
Magnetic tool for removing early stomach or colon polyps
This trial uses a special magnetic device to help doctors remove early-stage growths in the stomach or colon during a standard procedure called endoscopic submucosal dissection (ESD). The magnet pulls the tissue into a better position, which may make the removal safer and more effective.
Hong KongAges 18–85
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Common questions
- Are there clinical trials for colon cancer?
- Yes. Clin2 currently lists 290 recruiting colon cancer studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colon cancer trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colon cancer trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Beyond the search
We also like to point to nonprofits doing real good in this area. We aren’t affiliated with them — we just admire the work.
- Stand Up To CancerPeople facing cancer across many types, through the research that leads to better treatments.
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.