Clinical trials
Colorectal Surgery clinical trials
Below are recruiting colorectal surgery clinical trials, each written for real people, not researchers. We’re tracking 131 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06339671Recruiting
Recovery after surgery: smoking and complications
This study looks at how smoking habits affect recovery after colorectal surgery. It aims to understand if smokers have more complications than non-smokers, which could help tailor care before and after surgery.
MilanAges 18 years+ - NCT05826743Recruiting
Check a new alternative to ileostomy after bowel surgery
This trial tests whether a device called COLO-BT can be a safer, effective alternative to an ileostomy (a temporary or longer-term opening from the intestine to the skin). It’s for certain adults having a bowel connection low in the pelvis, where leak risk matters.
Buffalo, New YorkAges 19–80 - NCT06272461Recruiting
Comparing lidocaine vs. ketamine for colorectal surgery pain
This trial compares two pain-relief medicines (lidocaine vs. ketamine) given through an IV during open colorectal surgery. It aims to find which one works better to reduce pain after surgery.
NabeulAges 18–90 - NCT06405776Recruiting
Lidocaine for pain and survival after bowel surgery in older adults
This study tests whether a drug called lidocaine, given during surgery, can help control pain after colon or rectal surgery and possibly improve long-term survival in older adults. The goal is to see if lidocaine offers better pain relief and recovery compared to standard care.
SichuanAges 60 years+ - NCT07609680Recruiting
Blood Pressure vs. Heart Output Monitoring During Colon Surgery
This trial compares two ways doctors monitor your body's circulation during colorectal surgery. One method tracks blood pressure; the other tracks how much blood your heart pumps. Researchers want to see which approach leads to better outcomes and fewer complications.
Ankara, Yenimahalle\AnkaraAges 18–80 - NCT07615036Recruiting
Natural Opening Specimen Removal in Colon Surgery
This study tracks a newer surgical technique where the removed colon or rectum is pulled out through the body's natural opening (like the anus or mouth) instead of through a larger cut in the belly. Researchers want to understand how safe and effective this approach is compared to traditional methods.
SingaporeAges 21 years+ - NCT07144683Recruiting
Colorectal surgery leak study
This trial is studying how often leaks happen after colorectal surgery that connects two parts of the intestine. It may help doctors better understand and prevent this complication.
Minya, Minya GovernorateAges 18–80 - NCT04367987Recruiting
Heart Rate Changes After Colorectal Surgery
This study measures how your heart rate varies after planned colorectal surgery to see if these changes can predict complications. Researchers will monitor your heart rhythm before and after your operation to understand whether certain patterns might warn of problems early.
NîmesAges 18 years+ - NCT06212817Recruiting
Dietary fiber before colorectal cancer surgery
This study tests whether eating extra dietary fiber before colon cancer surgery helps recovery. You'll receive fiber-rich foods or a placebo for 2-3 weeks before your operation.
Arnhem, GelderlandAges 18 years+ - NCT06259149Recruiting
Timing of blood clot prevention after colorectal cancer surgery
This study looks at when to start blood thinners after surgery for colorectal cancer. The goal is to find the safest time to prevent blood clots without increasing bleeding risk.
Shanghai, Shanghai MunicipalityAges 18–110 - NCT06456229Recruiting
Probiotics after colorectal cancer surgery
This trial tests if taking probiotics (healthy bacteria) before and after surgery can help your bowels start working again sooner. It's for people having planned colorectal cancer surgery.
SingaporeAges 21–99 - NCT06657924RecruitingPhase 2
TXA to Prevent Bleeding in Colorectal Surgery
This trial tests a medicine called tranexamic acid (TXA) given right before major colorectal surgery to see if it helps reduce bleeding. If it works, it could make surgery safer for people like you.
Cleveland, OhioAges 18–100 - NCT06783244Recruiting
Low vs standard belly pressure for robot colorectal cancer surgery
This trial is testing whether using lower air pressure inside the belly during robot-assisted colorectal cancer surgery helps patients recover better compared to the standard pressure. It aims to find a gentler approach that might reduce pain and improve recovery.
Copenhagen NVAges 18 years+ - NCT06869096Recruiting
Flushing liquid during colorectal cancer surgery
This trial compares two different liquids used to flush the surgical area during colorectal cancer surgery to see which one better prevents infections. If you are having surgery for colorectal cancer, you may be able to join.
Nanchong, SichuanAges 18–85 - NCT07264556Recruiting
Comparing three anesthesia types for colorectal cancer surgery
This trial compares three types of anesthesia during colorectal cancer surgery to see how they affect the body's immune response and cancer cells. It may help find the safest and most effective anesthesia option for people having this operation for the first time.
Shanghai, Shanghai MunicipalityAges 18–80 - NCT07535021Recruiting
Mandala Art Therapy to Help With Cancer Surgery Recovery
This study tests whether creating mandala art (decorative circular patterns) helps colorectal cancer patients cope better after surgery. Researchers want to see if art therapy reduces stress, builds emotional strength, and improves your ability to handle the surgery and recovery.
SivasAges 18–74 - NCT07429760Enrolling by invitation
Bowel prep with or without antibiotics for left-sided colon surgery
This study compares two ways to prepare for left-sided colorectal cancer surgery: cleaning the bowel with liquid alone, or cleaning the bowel plus taking oral antibiotics beforehand. The goal is to see if adding antibiotics reduces infections after surgery.
Lahore, Punjab ProvinceAges 18–60 - NCT07380867Enrolling by invitation
New marker test for marking colon tumors before surgery
This trial tests a new marker that glows under special light to help doctors see exactly where a colon tumor is during surgery. It may help make the surgery more precise.
Seoul, SeoulAges 19–80 - NCT06958926Recruiting
Study of colon cancer that returns after surgery
This study looks at colon cancer that comes back in the same area after surgery. It may help doctors understand how to better treat this type of recurrence.
HsinchuAges 18 years+ - NCT04527861Recruiting
Minimally invasive single-incision surgery for colon cancer
This trial compares a single-incision laparoscopic operation versus the usual laparoscopic operation for colorectal (colon or “high rectum”) cancer. It looks at cancer outcomes and may help determine which approach is safer and works better for the right patients.
Lanzhou, GansuAges 18–85 - NCT06865638Recruiting
Testing for colorectal anastomotic leaks after surgery
This trial is testing a new method to check for leaks after colorectal cancer surgery. The goal is to see if it helps prevent complications and improves recovery.
Nanchong, SichuanAges 18–85 - NCT06225011RecruitingPhase 1
Can a common antidepressant help your immune system fight colorectal cancer before surgery?
This trial is testing whether a common antidepressant called fluoxetine (Prozac) can help your immune system fight colorectal cancer before surgery. It's for people with early-stage colorectal cancer who have not yet had treatment.
Los Angeles, CaliforniaAges 18 years+ - NCT03659448RecruitingPhase 3
Test drug that helps map colon and rectal cancer during surgery
This Phase 3 study tests SGM-101, a drug used during surgery to help doctors better outline primary, recurrent, and spread (metastatic) colorectal cancer. It may improve how completely tumors are identified and removed during an operation.
Duarte, CaliforniaAges 18 years+ - NCT05993923Recruiting
Geriatric team support for seniors having colorectal cancer surgery
This study tests whether a team of specialists (including a geriatric doctor) can help people aged 70+ recover better after colorectal cancer surgery. The goal is to see if this approach improves your daily functioning and independence after the operation.
Nîmes, FranceAges 70 years+
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Common questions
- Are there clinical trials for colorectal surgery?
- Yes. Clin2 currently lists 131 recruiting colorectal surgery studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a colorectal surgery trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a colorectal surgery trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.