TXA to Prevent Bleeding in Colorectal Surgery
Treatments studied
Part of Heart & circulation clinical trials.
This trial tests a medicine called tranexamic acid (TXA) given right before major colorectal surgery to see if it helps reduce bleeding. If it works, it could make surgery safer for people like you.
Summary written for real people, not researchers, by Clin2.
Who can take part
- You must be 18 or older.
- You are scheduled for major colorectal surgery (on your colon or rectum) that requires a hospital stay.
- You cannot have severe kidney disease (creatinine clearance < 30) or be on dialysis.
- You cannot be color blind.
- You cannot be pregnant.
- You cannot have a history of blood clots or a clotting disorder like DIC.
Quick eligibility check
Answer a few plain-language questions, based on this study's own requirements, to get a preliminary sense of fit.
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This trial tests whether tranexamic acid (a medicine that helps reduce bleeding) lowers bleeding during colon procedures where abnormal growths are removed with a flexible camera. You might benefit if you’re having one of these colonoscopic resection procedures and don’t have certain key risk factors.
This trial studies whether giving tranexamic acid (a medicine that helps reduce bleeding) during planned lower-back decompression surgery can lower blood loss or related complications. It compares patients who receive the infusion during surgery to those who meet study procedures and safety requirements.
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This trial tests if taking tranexamic acid (TXA) pills for a week after knee replacement surgery helps reduce bleeding and the need for blood transfusions. You may qualify if you are having a planned first-time knee replacement with spinal anesthesia and are already scheduled for standard care.
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