Clinical trials
Connective Tissue Diseases clinical trials
Below are recruiting connective tissue diseases clinical trials, each written for real people, not researchers. We’re tracking 85 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06672822RecruitingPhase 2
STS injections for calcinosis in scleroderma
This trial tests if injecting a medication called STS directly into calcium deposits can relieve pain and symptoms. It may help patients with scleroderma or related conditions who have painful calcium lumps.
Pittsburgh, PennsylvaniaAges 18 years+ - NCT07162415Recruiting
Ganglion resection for wrist pain
This trial tests if removing a wrist ganglion (a benign fluid-filled lump) helps reduce pain better than other treatments. It is for adults with wrist pain from a confirmed ganglion cyst who have not had wrist surgery before.
HelsinkiAges 18 years+ - NCT02611089Recruiting
Study of forearm development and reconstruction in limb conditions
This study looks at how connective tissue in the forearm develops and how it behaves in people needing reconstructive surgery. It may help surgeons better plan and improve reconstruction for conditions like radial dysplasia, or for other injuries requiring similar surgery.
Oxford, OxfordshireAges Any age - NCT06335628Recruiting
Building gum tissue for a missing tooth: graft comparison
This study tests two ways to build up gum tissue where a tooth is missing before placing an implant or bridge. It compares using a small piece of your own gum (connective tissue graft) versus a man-made collagen material to see which gives better volume and shape.
BernAges 18 years+ - NCT06474910Recruiting
Connective tissue massage for scleroderma patients
This study tests whether a special type of massage (connective tissue massage) helps improve hand function and skin tightness in people with scleroderma. It may be a good option if your scleroderma is stable and you can do light exercise.
ElâzığAges 18–65 - NCT06941129RecruitingPhase 1
CAR T-cell therapy for resistant autoimmune diseases
This trial tests a new type of immune therapy called CAR T-cells that target two markers on your B cells (CD19 and BCMA). It is for people with certain autoimmune diseases that have not improved or have come back after standard treatments. The goal is to see if this therapy can help control the disease.
TianjinAges 18 years+ - NCT07315087RecruitingPhase 1
CAR T-cell therapy for autoimmune diseases
This trial tests a special type of cell therapy (CAR T-cells) that targets two markers on immune cells, CD19 and BCMA, to calm overactive immune systems in people with certain autoimmune diseases. It's for those whose disease has not been controlled by standard treatments.
TianjinAges 18 years+ - NCT07649239Recruiting
Gum Grafting Methods for Dental Implants in Front Teeth
This trial compares two techniques to improve the appearance and health of gum tissue around dental implants in your front teeth. One uses a special blood product (PRF), and the other uses a traditional gum graft. The goal is to see which gives better-looking results.
Ajman, Ajman EmirateAges 20–70 - NCT05717985Recruiting
Gum tissue grafts using two modified surgical methods
This trial compares two ways of taking donor tissue from the roof of the mouth to rebuild gum/soft tissue. It may help people who need a gum tissue graft to improve the health and appearance of the oral area.
Kuala LumpurAges 18 years+ - NCT06469996Recruiting
Massage therapy for fibromyalgia pain
This study tests whether a special type of massage (connective tissue massage) can reduce pain and improve well-being in women with fibromyalgia. The massage targets the soft tissues under the skin to relieve muscle tension and pain.
ElâzığAges 18–65 - NCT06820489Recruiting
Comparing gum and bone healing after implant placement
This study tests three different ways to rebuild gum and bone around a new dental implant placed right after a tooth is pulled. It may help if you need a front tooth, canine, or premolar removed and have enough bone for the implant.
Ghent, East FlandersAges 20 years+ - NCT05715203Recruiting
Study of how stiff the aorta is in inherited aortic conditions
This study looks at how “stiff” the aorta (the body’s main artery) is in people with inherited aortic conditions. It may help researchers better understand the condition and how it progresses over time.
San Donato Milanese, LombardyAges Any age - NCT00470327Recruiting
Study of how interstitial lung disease naturally changes
This study looks at how interstitial lung disease (lung scarring) typically progresses over time. It may help researchers understand what to expect and what changes to watch for.
Chicago, IllinoisAges 18 years+ - NCT06837688Recruiting
Comparing two methods to improve gum around a single front tooth implant
This study compares two methods to improve gum tissue around a single dental implant in the front upper jaw. It may help you if you have a missing front tooth, healthy gums, and enough bone and gum width for an implant.
DamascusAges 18–60 - NCT07647276Recruiting
Massage and relaxation for period pain relief
This study tests whether connective tissue massage (a hands-on technique) and progressive relaxation exercises can reduce severe menstrual cramps. If you have primary dysmenorrhea—painful periods without an underlying medical cause—this trial may help you find natural pain relief.
DenizliAges 18–30 - NCT07150143Recruiting
Massage and exercises for chronic neck pain
This trial tests whether adding a special type of massage (connective tissue massage) and other physical therapies to standard neck stabilization exercises helps people with long-term neck pain feel better.
Ataşehir, IstanbulAges 18–65 - NCT03997578Recruiting
Gum surgery for deep periodontal bone defects
This trial studies a specific gum surgery technique plus a biologic product to help fill deep gum/bone defects from periodontitis (gum disease). It may help reduce gum pocket depth and improve healing around affected teeth.
MurciaAges 18 years+ - NCT07102758Recruiting
Comparing gum grafts for immediate dental implants
This trial tests two ways to support the gum around a new dental implant placed right after a tooth is pulled. It compares a special blood-clot material (L-PRF) to a connective tissue graft to see which heals better.
Kafr ash Shaykh, KafrelsheikhAges 21–45 - NCT07104019Recruiting
Biofiller for Thinning Gums: A Gum-Thickening Study
This study tests a biofiller to make thin gums thicker in the lower front teeth area. It may help people with thin gums who want to improve their gum health and appearance.
MalatyaAges 18–65 - NCT04467671RecruitingPhase 2
Tested new blood vessel graft for a heart surgery
This trial studies whether a newer “tissue-engineered” blood vessel graft is safe and works well in children who need a specific heart surgery connection outside the heart. It may help by offering a new type of graft, but your team will screen for size and medical factors first.
Columbus, OhioAges Any age - NCT04398628Recruiting
Study of non-cancer blood disorders in people with bleeding or clotting
This study follows people with inherited or acquired non-cancer blood disorders to better understand symptoms, causes, and how different treatments work over time. You may be placed into a disorder-specific group, depending on your diagnosis and testing results.
Phoenix, ArizonaAges Any age - NCT07333534Recruiting
Bone graft with or without gum graft for front tooth implants
This study compares two ways to rebuild bone and gum around a dental implant placed immediately after removing a failing front tooth. It may help patients who need a tooth replaced in the smile zone and have enough healthy bone to support the implant.
Baghdad, RusafaAges 18–65 - NCT07066982RecruitingPhase 1/Phase 2
CAR T cells targeting CD146 and HER2 for advanced sarcomas
This trial tests a new type of immunotherapy where your own immune cells are modified to find and attack sarcoma cells that carry markers called CD146 or HER2. It is for people with advanced sarcoma who have already tried standard treatments.
Beijing, Beijing MunicipalityAges 21–90 - NCT07590960Enrolling by invitation
Gum Grafting Surgery for Lower Front Tooth Root Coverage
This study tests a surgical technique to cover exposed tooth roots on the inside of your lower front teeth using gum tissue from the roof of your mouth. It may help reduce sensitivity and improve the appearance of receded gums.
Pittsburgh, PennsylvaniaAges 18–65
Hear when a new Connective Tissue Diseases trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for connective tissue diseases?
- Yes. Clin2 currently lists 85 recruiting connective tissue diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a connective tissue diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a connective tissue diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.