Clinical trials
Connective Tissue Diseases clinical trials
Below are recruiting connective tissue diseases clinical trials, each written for real people, not researchers. We’re tracking 87 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07486869RecruitingPhase 2
Emapalumab study for MDA5-related lung disease
This trial tests if emapalumab can help people with a serious lung condition linked to MDA5 antibodies. It may be an option for those with worsening breathing despite other treatments.
Miami, FloridaAges 18 years+ - NCT07368621Recruiting
Gum graft with or without platelet-rich fibrin for dental implant thickness
This trial tests if adding a special blood concentrate (platelet-rich fibrin) to a standard gum graft helps thicken the gum tissue around a dental implant. It is for people with thin gums who are missing a single tooth.
Cairo, Cairo GovernorateAges 18–60 - NCT07723872Recruiting
Finger vs. earlobe oxygen test during a 6-minute walk
This study compares oxygen levels measured at the finger versus the earlobe during a 6-minute walk test for people with interstitial lung disease. It helps find the most accurate way to monitor your oxygen during exercise.
Granollers, SpainAges 18 years+ - NCT04095351Recruiting
Study of connective tissue disease affecting the lungs
This study looks at people aged 18 and older who have a connective tissue disease and lung involvement. It aims to better understand how these lung problems progress and may help doctors choose better care.
InnsbruckAges 18–80 - NCT04402086Recruiting
Rheumatology patient and skin sample registry study at Yale
This study builds a health record and blood/skin sample collection for people with rheumatic autoimmune diseases who are getting care at Yale. It may help researchers understand these conditions and develop better tests or treatments over time.
New Haven, ConnecticutAges 18–99 - NCT05013944Recruiting
Join a patient registry to support future research
This trial is a “patient registry,” which collects health information over time to help researchers plan and run future studies. It may help by contributing your experience so new treatments can be tested more effectively.
Arlington Heights, IllinoisAges 18 years+ - NCT05440240RecruitingPhase 4
Needling and possibly steroid shot for Dupuytren’s hand tightness
This trial tests a minimally invasive procedure that uses a needle to release tight tissue in the hand, and may include a steroid injection. It aims to improve hand finger straightening for people with Dupuytren’s contracture.
SilkeborgAges 45–99 - NCT05665556Recruiting
Registry for pulmonary hypertension in connective tissue disease
This trial is a registry that collects health information from people with certain types of pulmonary hypertension linked to connective tissue diseases. It helps doctors understand patterns of disease and outcomes, which can guide future care and studies.
Mexico CityAges 18 years+ - NCT05998759RecruitingPhase 2
Telitacicept for low platelets from connective tissue disease
This trial tests a new medicine called telitacicept for people with connective tissue disease (like lupus or Sjögren's) whose platelet counts stay dangerously low despite standard treatments. It aims to raise platelet levels and reduce bleeding risk.
Hefei, AnhuiAges 18–75 - NCT06104228RecruitingPhase 2
Xenon MRI to detect and track pulmonary hypertension
This trial uses a special MRI scan (using xenon gas) to see how well the lungs are working in people with pulmonary arterial hypertension (PAH). It aims to improve diagnosis and monitoring of PAH from connective tissue disease or unknown cause.
Durham, North CarolinaAges 18–75 - NCT06455384Recruiting
Studying a digital tool for genetic testing services
This trial tests a new online tool called the Genetics Navigator, which helps people access genetic testing services more easily. If you or your child have been referred for genetic testing at Mount Sinai Hospital or SickKids in Toronto, this study may help you manage the process online.
Toronto, OntarioAges 18 years+ - NCT06399822Recruiting
Capillaroscopy for managing undifferentiated connective tissue disease
This study looks at whether a simple test called capillaroscopy (which examines tiny blood vessels in your fingernails) can help doctors better manage undifferentiated connective tissue disease. If you join, the test results will be used to guide your care, and researchers will see how it affects treatment decisions.
Québec, QuebecAges 18 years+ - NCT06499233RecruitingPhase 4
Study on preventing pneumocystis pneumonia in autoimmune disease
This trial tests whether a preventive treatment can stop pneumocystis pneumonia (a lung infection) in people with autoimmune inflammatory rheumatic diseases who are taking steroids or other immune-suppressing medicines. It aims to find the safest and most effective way to protect you from this serious infection.
Wuhan, HubeiAges 18 years+ - NCT06572384RecruitingPhase 3
Belimumab for lung scarring in autoimmune disease
This study tests whether a drug called belimumab can help people with lung scarring caused by certain autoimmune diseases (like rheumatoid arthritis or lupus). If you have active lung disease despite standard therapy, this trial may be an option.
Los Angeles, CaliforniaAges 18 years+ - NCT06574581RecruitingPhase 1/Phase 2
Adipose stem cells for connective tissue disease with lung scarring
This trial tests whether stem cells from fat tissue can help people with connective tissue diseases (like lupus or scleroderma) whose lung scarring has worsened despite standard treatments. It aims to slow or stop lung damage.
TaichungAges 20–80 - NCT06696027Recruiting
Loss of Y chromosome in autoimmune and lung disease
This study looks at how the loss of the Y chromosome in blood cells may be linked to autoimmune and lung diseases in older men. By joining, you help researchers understand this connection better.
Bonn, North Rhine-WestphaliaAges 50 years+ - NCT06702228Recruiting
Precision care for pulmonary fibrosis in Ireland
This trial is for people with scarring lung disease (pulmonary fibrosis) in Ireland. It aims to better understand and care for the condition, especially in families. The study will look at medical data and may help improve diagnosis and treatment.
DublinAges 18–85 - NCT06716606RecruitingPhase 3
Long-term safety of belimumab for lung disease in scleroderma and other connective tissue diseases
This study tests the long-term safety and effectiveness of belimumab for people with lung scarring caused by scleroderma or other connective tissue diseases. It is for patients who already completed a one-year study with belimumab and were not considered treatment failures.
Philadelphia, PennsylvaniaAges 18 years+ - NCT06779799Recruiting
Study of vocal cord lesions in autoimmune disease patients
This study examines vocal cord lesions, like 'bamboo' nodes, that cause voice changes (dysphonia) in people with autoimmune diseases such as lupus or rheumatoid arthritis. It aims to better understand and characterize these lesions to improve diagnosis and treatment.
BrestAges 18 years+ - NCT06917690RecruitingPhase 3
Testing oleogel-S10 for epidermolysis bullosa in Japanese patients
This trial tests a gel called oleogel-S10 on wounds caused by a rare skin condition called epidermolysis bullosa (EB). It is only for people of Japanese descent who have a specific type of EB called junctional or dystrophic EB. The gel is put on the wound to help it heal.
FukuokaAges 3 weeks+ - NCT07174102Recruiting
Looking at lung scans in rheumatoid arthritis and related diseases
This trial studies lung scans (HRCT) from patients with rheumatoid arthritis, interstitial lung disease, or connective tissue disease to better understand lung involvement. If you have one of these conditions and have had a lung CT, you may be able to help.
PragueAges 18 years+ - NCT07217522Recruiting
Genetics of pulmonary hypertension study
This study looks at the genes that may be linked to pulmonary hypertension. By providing a saliva sample and filling out a health survey from home, you can help researchers learn more about this condition.
Piscataway, New JerseyAges 18 years+ - NCT07482917Recruiting
Streamlining the diagnosis of interstitial lung disease
This study is testing a new way to speed up the diagnosis of interstitial lung disease (a group of lung scarring conditions). If you have symptoms or scan findings that suggest ILD but haven't been fully diagnosed yet, this trial may help you get a faster, clearer answer.
Granollers, BarcelonaAges 18 years+ - NCT07283081Recruiting
Nailfold capillaroscopy for new interstitial pneumonia diagnosis
This trial tests if a special microscope exam of your nailfold blood vessels (capillaroscopy) can help doctors better understand new cases of interstitial pneumonia. It may help identify underlying conditions without starting certain treatments first.
BordeauxAges 18 years+
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Common questions
- Are there clinical trials for connective tissue diseases?
- Yes. Clin2 currently lists 87 recruiting connective tissue diseases studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a connective tissue diseases trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a connective tissue diseases trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.