Clinical trials
Cornea clinical trials
Below are recruiting cornea clinical trials, each written for real people, not researchers. We’re tracking 26 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04439552Recruiting
MRI study during cornea cross-linking for keratoconus
This trial uses an MRI scan (and a close-up eye scan) to study what happens in the cornea during treatment for keratoconus. It may help doctors better understand how treatment works and who benefits most.
Boston, MassachusettsAges 8–35 - NCT05516004RecruitingPhase 2
Cornea strengthening treatment study for thinning corneas
This Phase 2 study tests whether a procedure called PXL‑Platinum 330 can safely and effectively strengthen corneas that are thinning (such as keratoconus or related conditions). It aims to see if the treatment can help stabilize or improve the cornea’s shape while keeping side effects low.
Boca Raton, FloridaAges 18 years+ - NCT03321201Recruiting
Glue or cautery for a first pterygium surgery
This study compares two methods used during surgery for a first-time pterygium (a non-cancer growth on the eye surface): using a special glue versus cauterization. It may help determine which method works better to keep the growth from coming back and to heal more smoothly.
SplitAges 18 years+ - NCT07768735Recruiting
Camera study for checking the clear front part of the eye
This study tests a special camera (called UNITY DX) that takes detailed pictures of the cornea, the clear front part of your eye. It aims to see if this camera can help doctors spot problems in the cornea earlier or more accurately.
Salt Lake City, UtahAges 22 years+ - NCT06211218Recruiting
AI screening for multiple corneal diseases
This study uses artificial intelligence to look at slit-lamp images of your eye to screen for different corneal diseases. It may help find problems early when they are easier to treat.
Tianjin, Tianjin MunicipalityAges Any age - NCT03918408RecruitingPhase 1
Platinum eye drops and light to slow keratoconus
This Phase 1 study tests whether a specific corneal cross-linking system (called PXL-Platinum 330) is safe and effective for people with progressive keratoconus, a condition that makes the cornea thin and bulge. The goal is to slow vision changes and see how well the treatment works in the short term.
Eugene, OregonAges 12–45 - NCT07608367Recruiting
Hydrogel glue for eye surface repair surgery
This trial tests a new hydrogel glue that may replace stitches during eye surface repair surgery. It could help your eye heal faster and more comfortably after procedures like pterygium removal or corneal repair.
Jinan, ShandongAges 18–85 - NCT07605572Recruiting
GLP-1 drugs and dry eye disease in type 2 diabetes
This study tests whether a diabetes and weight-loss medication called GLP-1 receptor agonists affects dry eye disease. Researchers want to see if this medication helps or worsens dry eyes in people with type 2 diabetes and obesity.
AthensAges 18 years+ - NCT07580040Recruiting
How Smoking Affects the Eyes in the Short Term
This study measures how cigarette smoking immediately affects your eyes' health and structure. Researchers compare current smokers to people who have never smoked to understand if smoking causes quick changes to the eye's surface and shape.
IstanbulAges 18–60 - NCT06601101RecruitingPhase 3
Insulin drops for faster healing after corneal crosslinking
This trial tests whether insulin eye drops can help the cornea heal faster after corneal crosslinking, a procedure to treat keratoconus. It is for people with keratoconus who do not have diabetes, severe dry eye, or certain other eye conditions.
Campinas, São PauloAges 14 years+ - NCT07435142Recruiting
Urine-derived cells for corneal eye disease
This trial tests if using special cells from your own urine can help repair the inner layer of your cornea (the clear front part of your eye). It may be an option if you have damage to these cells and have already had at least one cornea transplant.
Jinan, ShandongAges 18–85 - NCT06830538Recruiting
Recovery and quality of life after corneal transplant
This study looks at how well people recover after a corneal transplant, including their vision, eye health, and overall quality of life. It aims to learn what helps people heal best after surgery.
BolognaAges 18 years+ - NCT07343011Recruiting
Conjunctival Surgery for Pterygium Treatment
This trial tests a surgery to move a piece of the conjunctiva (the clear tissue covering the white of the eye) to treat a primary pterygium, which is a growth on the eye's surface that extends onto the cornea. It may help prevent the growth from returning and improve comfort and vision.
Zahedan, Sistan and BalochistanAges 18 years+ - NCT07294716Recruiting
New lens for cataract patients with irregular corneas
This trial tests a special type of lens implant (asymmetric toric intraocular lens) for people having cataract surgery who also have an irregularly shaped cornea. The goal is to see if this lens can improve the quality of your vision after surgery.
LinzAges 21 years+ - NCT07124910RecruitingPhase 3
Comparing two UV light times for corneal crosslinking
This trial tests two different UV light exposure times (18 minutes vs. 24 minutes) during a corneal crosslinking procedure for people with keratoconus or similar corneal thinning conditions. The goal is to see if the shorter time works as well as the longer one.
Atlanta, GeorgiaAges 8 years+ - NCT06963099Recruiting
INTACS for high astigmatism in healthy corneas
This trial tests a procedure called INTACS, which uses small plastic rings to reshape the cornea and reduce high astigmatism. It is for people whose corneas are healthy and not bulging or thinning.
SohagAges 18–60 - NCT06967792Recruiting
Safety of Terahertz Eye Scan for Blind Eyes
This trial tests a new scanning system that uses safe terahertz waves to look at the cornea. It's for people who are blind in one eye but have a healthy cornea, to see if the scan is safe.
Singapore, SingaporeAges 21 years+ - NCT06969586Enrolling by invitation
Eye drops study for Fuchs corneal disease and glaucoma
This study tests whether special eye drops (Rho-kinase inhibitors) can improve the health of the cornea in people who have both Fuchs endothelial corneal dystrophy and glaucoma. The drops may help reduce corneal swelling and preserve your vision.
Zagreb, CroatiaAges 40–90 - NCT03504800Recruiting
Using OCT scans to diagnose irregular corneas
This study tests whether a special eye scan called OCT can better identify causes of irregular cornea shape. Results may help doctors sort out different cornea problems so treatment choices, like certain procedures, can be more targeted.
Portland, OregonAges 14–85 - NCT04570020Recruiting
Check how well wide-view scans guide scleral lens fitting
This study tests whether a special wide-area eye scan (OCT) can help fit scleral contact lenses more accurately. It may help people who need scleral lenses because of certain cornea shape problems or after past eye surgeries.
Portland, OregonAges 18 years+ - NCT05759780Recruiting
Check how an eye probe measures tissue softness
This study uses a special eye/skin/gum imaging test to measure how tissues behave. It may help researchers improve noninvasive ways to understand eye and tissue health, and in some parts of the study, mild keratoconus.
Boston, MassachusettsAges 18–75 - NCT02886611Recruiting
Study for genetic eye surface stem cell problems
This trial studies people whose eye surface problems are caused by an inherited (genetic) condition. It aims to better understand how specific genetic changes relate to symptoms, which may guide more personalized care.
ParisAges Any age - NCT04848740Enrolling by invitation
Tested implant for worsening thin corneas
This trial looks at whether placing a donor-like cornea “lenticule” implant can help people whose cornea is getting worse, becoming thin, and causing blurry or reduced vision. The goal is to see if the implant can improve corneal clarity and vision in progressive disease.
PristinaAges 20–60 - NCT04232982Recruiting
Cyclophotocoagulation during Boston keratoprosthesis eye surgery
This trial looks at whether a specific eye laser treatment done through the white of the eye (called transscleral cyclophotocoagulation) works well and is safe for people getting a Boston keratoprosthesis. It may help improve comfort and vision outcomes for selected patients needing this type of cornea/eye replacement surgery.
Montreal, QuebecAges 18–80
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Common questions
- Are there clinical trials for cornea?
- Yes. Clin2 currently lists 26 recruiting cornea studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a cornea trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a cornea trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.