Clinical trials
Crohn’s disease clinical trials
A type of inflammatory bowel disease causing inflammation of the digestive tract. We’re tracking 333 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07504510Recruiting
Exclusive liquid nutrition for active Crohn's disease
This trial tests whether a special liquid-only diet (exclusive enteral nutrition) can help people with active Crohn's disease, including those with complications like fistulas or narrowing of the intestine. It aims to improve nutrition and reduce disease activity without medication.
Guangzhou, GuangdongAges 18 years+ - NCT06800326Recruiting
Comparing MRI and ultrasound for Crohn's treatment response
This trial compares two types of scans—MRI and ultrasound—to see how well they detect changes in Crohn's disease after treatment. If you've had one of these scans already and need another to check your response to therapy, you may be able to join.
LondonAges 16–99 - NCT07403968RecruitingPhase 2
Study of Zasocitinib for Active Crohn's Disease
This trial tests a new oral medicine called Zasocitinib for people with active Crohn's disease who have tried other treatments that no longer work or are not tolerated. The goal is to see if it can reduce inflammation and improve symptoms.
OxfordAges 18–75 - NCT07310095RecruitingPhase 4
Study of ustekinumab for Crohn's disease with loss of response
This study tests a new treatment for people with Crohn's disease who have lost response to ustekinumab (Stelara). It aims to see if a different dosing or additional treatment can help regain control of symptoms.
GuangzhouAges 18 years+ - NCT06902987RecruitingPhase 1
Upatinib for anal fistulas in Crohn's disease
This trial tests whether upatinib can help heal active anal fistulas in people with moderate to severe Crohn's disease. If you have an anal fistula that is causing pain or drainage, this study may offer a new treatment option.
Guangzhou, GuangdongAges 18–70 - NCT06912815Recruiting
Ustekinumab and nutrition before Crohn's surgery
This trial tests if combining a drug called ustekinumab with a special liquid diet (semi-exclusive enteral nutrition) is as effective as using only the liquid diet to improve outcomes before Crohn's surgery.
Guangzhou, GuangdongAges 18–65 - NCT06925594RecruitingPhase 3
Cell injection for Crohn's-related anal fistulas
This trial tests a new cell injection (TH-SC01) to treat anal fistulas caused by Crohn's disease. It aims to see if the injection can heal fistulas and lower infection risk.
Nanjing, JiangsuAges 18–70 - NCT07184931RecruitingPhase 3
Testing duvakitug for active Crohn's disease
This study tests a new drug called duvakitug for people with moderately to severely active Crohn's disease who haven't responded well to other treatments. It aims to see if the drug can reduce symptoms and improve quality of life.
Peoria, ArizonaAges 16–80 - NCT07184944RecruitingPhase 3
Study of Duvakitug for moderate to severe Crohn's disease
This study tests a new drug called duvakitug to see if it can help maintain improvement in people with moderate to severe Crohn's disease. It's for patients who have already responded to treatment in a previous study.
Colorado Springs, ColoradoAges 16–80 - NCT07078994RecruitingPhase 2
Study of a new drug for moderate to severe Crohn's disease
This trial tests a new medicine called BCD-261 for people with moderate to severe Crohn's disease that has not responded well to other treatments. It aims to see if the drug can reduce symptoms and inflammation.
Barnaul, Altayskiy KrayAges 18–75 - NCT05805020Recruiting
Testing a camera tool to check Crohn’s bowel margins
This study looks at using a special handheld imaging tool during surgery to better check the edges (“margins”) of bowel removed for Crohn’s disease in the ileum/near the cecum. It may help surgeons ensure they remove the right tissue and potentially improve surgical planning.
AmiensAges 18 years+ - NCT06958159Recruiting
Comparing treatments for short Crohn's strictures
This trial tests a new approach that combines two procedures (stricturotomy and balloon dilation) against stricturotomy alone to treat short narrowed areas (strictures) caused by Crohn's disease. The goal is to see which method works better for keeping the bowel open longer.
Hyderabad, TelanganaAges 18–65 - NCT06203782Recruiting
Comparing two treatments for Crohn's disease strictures
This trial compares two ways to treat narrowed areas (strictures) in the gut caused by Crohn's disease: endoscopic strictureplasty versus balloon dilation. It aims to see which method works better for people whose strictures are manageable with a scope.
Hangzhou, HangzhouAges 18–75 - NCT06939712Recruiting
Online mental health program for Crohn's patients
This study tests an online program that uses positive psychology to help improve mental health and quality of life in people with Crohn's disease who have mild anxiety or depression. The program is done over the internet, so you can join from home.
Hangzhou, ZhejiangAges 18–75 - NCT06882993Recruiting
Testing a gentler approach to diagnose Crohn's disease
This trial tests a new, gentler way to diagnose Crohn's disease. If you have symptoms like long-lasting diarrhea or belly pain, this study may help find out if you have Crohn's without invasive procedures.
EsbjergAges 18–40 - NCT06719778Recruiting
Diet and lifestyle changes for Crohn's disease
This study tests whether changing your diet and lifestyle can help repair the lining of your gut if you have Crohn's disease. It focuses on people whose Crohn's causes food-related symptoms or IBS-like symptoms, and involves a special scope procedure to check for food-triggered gut barrier damage.
Bamberg, BavariaAges 18 years+ - NCT06647615Recruiting
Virtual reality for stomach pain in Crohn's disease
This study tests if using a virtual reality (VR) program can help reduce stomach pain in people with Crohn's disease that is not currently active. You will try the VR experience and report how your pain changes.
Jacksonville, FloridaAges 18–70 - NCT06548542RecruitingPhase 2
Targeted drug study for moderate to severe Crohn's disease
This trial tests new targeted therapies for adults with moderate to severe Crohn's disease that hasn't improved with standard treatments. The goal is to see if these drugs can reduce inflammation and improve symptoms.
Dothan, AlabamaAges 18–75 - NCT06512597Recruiting
Behavioral therapy for active Crohn's disease
This study tests whether a behavioral therapy program can help people with active Crohn's disease feel better when they start a new biologic medication. You'll get extra support to manage stress and symptoms while you and your doctor adjust your treatment.
New York, New YorkAges 18–65 - NCT06324838Recruiting
Surgery study for Crohn's disease in the ileocecal area
This trial compares two surgical techniques for removing the affected part of the intestine in people with Crohn's disease. It aims to see if removing more tissue around the blood vessels leads to better outcomes.
OdenseAges 18 years+ - NCT06233461RecruitingPhase 2
A study of TAK-279 for Crohn's disease
This study tests an oral medication called TAK-279 to see if it can safely reduce inflammation in the bowel for people with moderate to severe Crohn's disease who haven't had success with other treatments.
Murrieta, CaliforniaAges 18–75 - NCT06227910RecruitingPhase 3
Study of vedolizumab with or without upadacitinib for Crohn's disease
This trial tests combining two medicines, vedolizumab and upadacitinib, to see if they work better together than vedolizumab alone for people with moderate to severe Crohn's disease that hasn't responded well to other treatments.
La Jolla, CaliforniaAges 18–65 - NCT06006039Recruiting
Study on immune cells and Crohn's disease recurrence after surgery
This study looks at how certain immune cells relate to Crohn's disease coming back after bowel surgery. The goal is to better understand why some patients have a recurrence, which could help improve future treatments.
Toronto, OntarioAges 18 years+ - NCT05837897RecruitingPhase 3
Vedolizumab for adults with moderate-to-severe Crohn’s
This Phase 3 study tests whether vedolizumab can better control moderate-to-severe Crohn’s disease in adults whose symptoms haven’t improved enough with other treatments. You’d need to meet specific symptom scores, recent colonoscopy findings, and safety checks (including infections and vaccination status).
Hefei, AnhuiAges 18–80
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Common questions
- Are there clinical trials for crohn’s disease?
- Yes. Clin2 currently lists 333 recruiting crohn’s disease studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a crohn’s disease trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a crohn’s disease trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.