Clinical trials
Dementia clinical trials
Below are recruiting dementia clinical trials, each written for real people, not researchers. We’re tracking 492 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07182019Recruiting
Connecting families to fight loneliness in dementia
This study tests a program that helps people with dementia and their loved ones stay in touch through video calls. It aims to reduce social isolation and improve well-being.
Edmonton, AlbertaAges 65 years+ - NCT05514106Enrolling by invitationPhase 4
MIBG heart scan study for aging and neurologic conditions
This Phase 4 study tests how an iodine-based heart scan (a special imaging test) works in people with certain neurologic diagnoses and aging-related conditions. It may help researchers better understand the heart-brain connection in these disorders and improve future care.
Rochester, MinnesotaAges 40–90 - NCT07660263Recruiting
Predicting dementia after stroke with genetics and imaging
This study aims to develop a tool that predicts the risk of dementia after a stroke using genetic and imaging data. It enrolls both healthy adults and people who have had a stroke in the last 3 years.
Gyeonggi-do, Gyeonggi-doAges 19 years+ - NCT07730957Recruiting
Music program to reduce care refusal in nursing home residents
This trial tests whether a structured music program can help reduce care refusal (like agitation or aggression during bathing) in nursing home residents with memory or thinking problems. Residents who show these behaviors may be eligible.
AmiensAges 18 years+ - NCT07731334Recruiting
Memory problems in non-neurology rehab patients
This study looks at how common mild cognitive impairment and dementia are in people staying in rehabilitation units for heart, lung, or orthopedic problems. It aims to understand memory and thinking issues that may be overlooked in these settings.
Florence, FIAges 45 years+ - NCT05552157RecruitingPhase 2/Phase 3
Study of treatments for early onset Alzheimer's caused by genetic mutations
This trial tests potential treatments for people who are at risk for or have early onset Alzheimer's disease due to a specific genetic mutation. It aims to find treatments that could slow or prevent symptoms.
Birmingham, AlabamaAges 18 years+ - NCT06647498RecruitingPhase 2/Phase 3
Study of a treatment for early-onset Alzheimer's caused by a gene change
This study tests a potential disease-modifying treatment for people who have a specific gene mutation that causes early-onset Alzheimer's disease. The goal is to see if the treatment can delay or prevent symptoms.
Birmingham, AlabamaAges 18 years+ - NCT06052254RecruitingPhase 2
Skin patch for agitation in Alzheimer's dementia
This trial tests a skin patch that delivers a medicine called dexmedetomidine to help calm agitation in people with Alzheimer's disease. It might be an option for those living in a care facility who have had recent episodes of agitation.
Daytona Beach, FloridaAges Any age - NCT07114458Recruiting
Delirium and Thinking Changes in Older Hospital Patients in Isolation
This study looks at how being in isolation in the hospital might affect confusion or thinking problems in older adults. You may be eligible if you are 70 or older and have been in isolation for at least 24 hours.
Hamburg, Free and Hanseatic City of HamburgAges 70 years+ - NCT07717567Recruiting
Blood tests to diagnose and predict Alzheimer's disease
This study is testing whether a simple blood test can help diagnose Alzheimer's disease and predict how the disease will progress. If you have memory or thinking problems that have been getting worse, you may be able to join.
Milan, MilanoAges 40 years+ - NCT05139290Enrolling by invitation
Support for African American families managing dementia care decisions
This study focuses on helping African American people with mild to moderate dementia and their family caregivers make better care decisions together. It also includes people who help with navigating healthcare when dementia care becomes harder.
Washington D.C., District of ColumbiaAges 18 years+ - NCT06919926RecruitingPhase 2
Testing AGB101 for brain health in older adults
This study tests whether a medication called AGB101 (levetiracetam) can reduce overactivity in the hippocampus, a brain area important for memory. It is for healthy older adults who do not have memory problems, to see if the drug can help keep the brain working well.
Baltimore, MarylandAges 50–80 - NCT03135327Recruiting
Eye scans study to compare brain and eye health
This study uses detailed eye imaging to look for patterns that may go along with conditions like Alzheimer’s disease, memory problems, multiple sclerosis, or eye/vascular issues. It may help researchers better understand how eye findings relate to health and disease.
Miami, FloridaAges 18–99 - NCT03489278Recruiting
Support procedures study for ALS using electronic health records
This study is about improving the research process for people with ALS by using electronic health records from participating clinics. If you have ALS and receive care at an Epic-using center, you may be asked to help with consent and study procedures.
Irvine, CaliforniaAges 18 years+ - NCT03592563Recruiting
Brain health follow-up study for adults
This study follows adults over time to better understand brain health and brain-related conditions. You may join if you already have certain neurological or psychiatric diagnoses, are at higher risk, or simply want to help research on maintaining brain health.
Hong KongAges 18 years+ - NCT03621839Recruiting
Study of new spinal-fluid tests for Alzheimer’s disease
This study looks at new test markers found in spinal fluid to help with diagnosing Alzheimer’s disease. If you are already getting a spinal-fluid sample as part of your dementia workup, this trial may check it for additional information.
Nancy, Grand EstAges Any age - NCT03638583Recruiting
Online testing study to prevent or spot Alzheimer’s early
This study invites people age 50+ who do not have dementia to do ongoing thinking tests online. If an online risk screen suggests you may be at higher risk, you may be referred for in-person body tests (biomarker assessment).
San Diego, CaliforniaAges 50–85 - NCT03657745Recruiting
40 Hz light and brain training for Alzheimer’s
This trial tests whether a combination of 40 Hz light stimulation and cognitive (thinking) therapy can improve symptoms in people with Alzheimer’s disease. It may help by stimulating the brain and training thinking skills, while carefully checking eye and seizure history.
Miami, FloridaAges 50 years+ - NCT03702907Recruiting
Study of aging and a brain sample bank
This study follows adults as they age and may collect biological samples for future research. It could help researchers understand early and late changes related to aging and brain health.
Washington D.C., District of ColumbiaAges 45 years+ - NCT03848312RecruitingPhase 3
Preventing Alzheimer’s with brain training for older adults
This Phase 3 study tests whether structured computer brain-training can help prevent Alzheimer’s-related thinking problems. You may be more likely to benefit if your thinking is currently normal, and you can safely do the computer exercises every schedule the study requires.
Gainesville, FloridaAges 65 years+ - NCT03890861Recruiting
Exercise program to help lower Alzheimer’s risk
This trial studies whether a structured group exercise program can help lower Alzheimer’s disease risk in older African Americans. You would be assigned to a group by chance and asked to attend regular sessions if it’s safe for you to exercise.
Baton Rouge, LouisianaAges 60 years+ - NCT03934957Recruiting
Study of health in people living in Hamburg
This study follows adults living in Hamburg to better understand health and health-related factors over time. You may help researchers learn what influences health in this age group.
HamburgAges 45–74 - NCT03987633Recruiting
Study links health records and samples to understand health gaps
This study asks people affected by a specific illness (or their family member) to share saliva (and sometimes blood) and answer health and quality-of-life questions. The goal is to better understand and reduce health inequality by matching new information with medical records.
Wolverhampton, West MidlandsAges 6 years+ - NCT04165109Recruiting
Down syndrome study to test memory and thinking changes
This study enrolls adults with Down syndrome to better understand how thinking and memory develop and change over time. It may help by building a “trial-ready” group and by measuring thinking in a careful, consistent way.
Phoenix, ArizonaAges 25–55
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Common questions
- Are there clinical trials for dementia?
- Yes. Clin2 currently lists 492 recruiting dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.