Clinical trials
Dementia clinical trials
Below are recruiting dementia clinical trials, each written for real people, not researchers. We’re tracking 492 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT04961450Enrolling by invitation
Study tracking brain illness markers in motor neuron and frontotemporal disease
This study looks for “biomarkers” (measurable signs in blood or other samples) in people with motor neuron disease and frontotemporal dementia spectrum conditions. It also compares those findings with matched caregivers, to understand what might be happening in these diseases.
Beijing, Beijing MunicipalityAges 18–80 - NCT04701177Enrolling by invitation
Smartphone-based study of brain biomarkers in memory clinic patients
This observational study follows people with (or at risk for) Alzheimer’s-related brain changes and a comparison group without them. It uses clinic visits, cognitive testing, questionnaires, and possibly a spinal fluid test to better understand brain biomarkers and how they relate to thinking and daily life.
Corfu, CorfuAges 45 years+ - NCT04680130Enrolling by invitation
Study of brain, genetics, and clinical symptoms in neurodegenerative illness
This study looks at how your symptoms, brain imaging (MRI), and genetic factors relate to neurodegenerative conditions. It may help researchers better understand what causes these illnesses and how to classify them.
Rochester, MinnesotaAges 21 years+ - NCT07775833Recruiting
Mushroom supplement to slow memory decline in at-risk adults
This trial tests whether eating mushrooms regularly can help prevent memory loss in people who are at higher risk for Alzheimer's disease but do not have dementia. If you are between 45 and 80, have some memory concerns, and currently eat mushrooms rarely, this study may be a good fit.
SingaporeAges 45–80 - NCT07550075Recruiting
Support program for Korean American dementia caregivers
This study tests a virtual support program designed specifically for Korean American adults who care for family members with dementia. The program aims to help caregivers manage stress and learn practical caregiving skills through online classes.
Los Angeles, CaliforniaAges 18 years+ - NCT05586581RecruitingPhase 1/Phase 2
PET and MRI scans to study brain changes in treated HIV
This study uses PET and MRI scans, plus blood tests and memory/thinking questionnaires, to understand what drives brain problems in people living with HIV even during treatment. It may help researchers learn why symptoms happen and how treatment relates to brain function.
New Haven, ConnecticutAges 18–80 - NCT05617014Enrolling by invitation
ADNI4 study for early Alzheimer’s with brain imaging tests
This study enrolls people with no memory impairment, mild memory problems, or mild Alzheimer’s dementia to test how brain scans and cognitive tests relate to Alzheimer’s disease. It may help by contributing to better early diagnosis and by letting you see whether you fit into the study’s imaging and blood-test pathway.
Birmingham, AlabamaAges 55–90 - NCT07763392Recruiting
Normal cognitive test scores for adults
This study is testing a voice-controlled digital platform to measure normal memory and thinking abilities in healthy adults. By participating, you would help create a baseline of normal scores that doctors can use to compare against when assessing people with thinking problems.
Carlsbad, CaliforniaAges 18–100 - NCT07758660Enrolling by invitationPhase 2
Brain scan study for Alzheimer's research
This study uses brain scans (PET) to look at changes in the brain that may be related to memory problems or Alzheimer's disease. It aims to improve understanding of the disease and may help develop better treatments.
New York, New YorkAges 50 years+ - NCT07688213RecruitingPhase 2
Study of an investigational drug for early Alzheimer's disease
This trial tests an investigational injection for people in the early stages of Alzheimer's. It aims to see if the drug can safely slow down memory loss and brain changes.
The Villages, FloridaAges 55–85 - NCT05879211Enrolling by invitation
Care learning lab for Duke Health patients
This trial is a “learning laboratory” that studies how best to provide goal-focused care. It may help improve care experiences for Duke Health patients, based on what the study learns.
Durham, North CarolinaAges 18 years+ - NCT07216716Recruiting
Health app recommendation tool for Alzheimer's caregivers
This study tests a tool that helps find health apps for people caring for a loved one with Alzheimer's or a related dementia. It aims to see if the tool makes it easier to choose useful apps for your caregiving journey.
Pittsburgh, PennsylvaniaAges 18–65 - NCT06922071Recruiting
Memory support program for older adults in care
This study offers a memory- and thinking-support program for older adults who are living in a residential facility or attending a daycare center. The goal is to help keep your mind sharp and maintain your well-being as you age.
Coimbra, PortugalAges 65 years+ - NCT06871839Recruiting
A study of lencanumab for early Alzheimer's disease
This trial tests an investigational drug called lencanumab for people with early Alzheimer's disease. The goal is to see if it can help with memory and thinking by targeting brain changes caused by Alzheimer's.
BeijingAges 50–90 - NCT05910619Recruiting
Noninvasive brain stimulation to support memory and thinking
This study tests a noninvasive way of stimulating the brain to see if it can help older adults with typical age-related changes or mild memory problems. You may be invited if your screening tests and health history fit one of their target groups.
Gainesville, FloridaAges 65–84 - NCT04956549Recruiting
Exercise program for early memory loss in African Americans
This study tests whether a structured exercise program can lower Alzheimer’s risk in older African American adults who have mild cognitive impairment (MCI). You’ll be placed by chance into an exercise group or a comparison group and attend group sessions for about a year.
Baton Rouge, LouisianaAges 60 years+ - NCT05740683Recruiting
Studies alpha-synuclein and brain symptoms in smell loss
This study looks at whether a specific brain protein (alpha-synuclein) is linked to other neurologic symptoms in people who have long-lasting smell loss. It may help researchers understand what causes smell loss and how it relates to later brain or nerve changes.
CopenhagenAges 55–75 - NCT06746909Recruiting
Brain inflammation and imaging in older adults at risk for dementia
This study looks at how changes in the brain (like inflammation) relate to thinking and memory decline in older adults. It uses brain scans and computer tools to find early signs of dementia risk, with the goal of better preventing memory loss.
PisaAges 65–89 - NCT07096960Recruiting
Testing a caregiver support program for dementia in Brazil
This trial is testing a support program called START for family caregivers of people with dementia in Brazil. It aims to see if the program can be put into practice and if it helps caregivers feel less stressed.
Vitória, Espírito SantoAges 18 years+ - NCT06429215Recruiting
Virtual reality and telemedicine to lower dementia risk
This trial tests whether a program using virtual reality and telemedicine can help lower the risk of memory decline and dementia in people who feel their thinking is slipping but don't have a diagnosed memory problem.
Rome, LazioAges 55–80 - NCT07409506Recruiting
How caregivers help people with Alzheimer's
This study looks at the support that caregivers provide to people with Alzheimer's disease at different stages. It helps researchers understand how caregiving changes over time, which can lead to better support for both patients and their families.
VilleurbanneAges 60 years+ - NCT07321587Recruiting
Walking, texts, and videos for older adults and their care partners
This study tests whether a program of Fitbit tracking, text reminders, exercise videos, and walking with a care partner can help older adults (with or without mild dementia) become more active. It is designed for people who are willing to use a smartwatch and stay connected via phone or internet.
New York, New YorkAges 18 years+ - NCT07040904Recruiting
Mindfulness to help older Latino adults stay mentally sharp
This study tests whether mindfulness training can help older Latino adults stay sharp as they age. Researchers will measure changes in thinking skills and brain health.
St Louis, MissouriAges 65 years+ - NCT07724132RecruitingPhase 3
Treatments for sustained response in Alzheimer's disease
This study tests whether a treatment (atomoxetine or metformin) can help people with Alzheimer's disease maintain an improved state for at least 18 months. It may help you or a loved one stabilize symptoms and slow disease progression.
CambridgeAges 55 years+
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Common questions
- Are there clinical trials for dementia?
- Yes. Clin2 currently lists 492 recruiting dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.