Clinical trials
Dementia clinical trials
Below are recruiting dementia clinical trials, each written for real people, not researchers. We’re tracking 492 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05245903Recruiting
Test a supplement and track brain changes with wearable sensors
This study tests whether taking nicotinamide riboside (a form of niacin) affects early memory changes in people with mild cognitive impairment (MCI) or mild Alzheimer’s disease (AD). It also uses passive wearable or sensor data (“digital biomarkers”) to measure changes over time.
Belmont, MassachusettsAges 18–89 - NCT05288842Recruiting
Study spinal fluid and brain changes in dementia types
This study looks at spinal fluid and MRI results in people with Alzheimer’s disease, frontotemporal dementia, or normal thinking (controls). It aims to understand differences in brain-related cells and measure what might help explain or track these conditions.
LilleAges 40–85 - NCT05296980Recruiting
Testing a dementia risk-reduction program for older adults
This study checks whether a program called REMINDER can help reduce risk of developing dementia by improving risk factors over 12 weeks. It’s for older adults who have higher dementia risk but do not currently have dementia.
CoimbraAges 60–75 - NCT05306834Recruiting
Study to slow memory decline by targeting hidden small brain vessel disease
This trial looks at how to slow cognitive decline and early dementia in people with a specific kind of “silent” blood vessel damage in the brain seen on scans. It may help identify whether targeting this hidden condition can protect thinking and memory over time.
BordeauxAges 60–88 - NCT05326750Recruiting
Brain stimulation to help diagnose and manage memory conditions
This trial studies a non-invasive brain-stimulation approach to help doctors assess and manage certain brain-related conditions. You might benefit by contributing to better diagnostic tools and treatment planning for memory and thinking problems.
KuopioAges 18 years+ - NCT05397639RecruitingPhase 3
Masupirdine trial for agitation in Alzheimer’s dementia
This Phase 3 study tests masupirdine to see if it can reduce agitation in people with Alzheimer’s-type dementia. If you have Alzheimer’s dementia with confirmed agitation, joining could help researchers find better treatment options.
Anaheim, CaliforniaAges 50–90 - NCT05407857Recruiting
Study to help prevent memory decline in adults over 60
This study looks for ways to lower the risk of developing dementia and improve thinking skills in people over 60. You may be eligible if you do not have dementia but have early warning signs of memory or thinking changes.
New Taipei CityAges 60–90 - NCT05520268Recruiting
Music therapy plus digital rehab for dementia symptoms
This study tests whether music therapy and a digital music program can improve symptoms and daily functioning in people living with dementia. It may help support memory, mood, or communication by using music-based activities.
HelsinkiAges 60 years+ - NCT05561205Recruiting
Brain stimulation to treat persistent apathy
This trial tests a noninvasive brain stimulation treatment (called rTMS) to help people who have had ongoing apathy (lack of motivation/interest) for at least a month. You might benefit if your apathy is persistent, your other symptoms are stable, and you meet the safety and medication rules.
Toronto, OntarioAges Any age - NCT05582161RecruitingPhase 2
Test drug target for Alzheimer’s or memory loss
This Phase 2 study looks at how well a medicine that targets DAO (an enzyme in the body) helps people with Alzheimer’s disease or mild cognitive impairment. You may be considered if your memory symptoms are mild to moderate and you meet specific brain-function and symptom scoring rules.
Kaohsiung CityAges 50–90 - NCT05592366Recruiting
Testing a hospital tool for unpaid dementia caregivers
This study is testing a care-partner support tool for people who provide unpaid care to a hospitalized adult loved one or partner with dementia-related needs. It may help caregivers and hospitals communicate and coordinate better during a hospital stay.
Madison, WisconsinAges 18 years+ - NCT05592678Recruiting
Study brain and memory test changes in Alzheimer’s or mild issues
This study looks at how well people with Alzheimer’s disease (AD) or mild cognitive impairment (MCI) perform on standardized memory/brain tests. It may help researchers understand changes over time, and whether certain types of brain signals or test results track with the condition.
San Antonio, TexasAges 65–100 - NCT05603533Recruiting
Music group sessions to help people with dementia exercise
This trial studies whether guided group exercise with music can improve how well people with moderate dementia follow exercise plans. Participants will join a nursing-home based music and movement group program.
Kasterlee, AntwerpenAges 65 years+ - NCT05623124Recruiting
Alzheimer’s and dementia brain and memory study with caregiver support
This is a study that enrolls people with mild Alzheimer’s-related memory problems or dementia to help build a research “neurobank.” It also involves memory testing and may include brain scans, with a stable caregiver to support follow-up.
Shanghai, Shanghai MunicipalityAges 50–90 - NCT05649800Recruiting
Study brain and blood-vessel changes in older adults after stroke
This study looks at how blood flow in the brain and related brain processes change after stroke, especially when someone also has conditions like dementia, depression, or delirium. It may help researchers understand what drives these problems and how they connect.
Leicester, LeicestershireAges 65 years+ - NCT05655403Recruiting
Step training for older adults with mild dementia
This trial studies whether a structured “step training” exercise program can help people with mild dementia move better or think more clearly. It may be helpful if you can walk independently and have a regular caregiver at home.
Hong KongAges 65 years+ - NCT05661084Recruiting
Non-surgery brain stimulation for dementia thinking and movement
This study tests whether a non-invasive brain stimulation device (tES) can improve thinking and movement problems in people with dementia. You (and your caregiver, if needed) will be asked to follow the study plan and attend visits so researchers can measure results and safety.
Boston, MassachusettsAges 55 years+ - NCT05691569Recruiting
Doll therapy for agitation in moderate to severe dementia
This trial tests whether using a realistic doll can reduce agitation and aggressive behaviors in people with moderate to severe dementia during a hospital stay. It may help some patients feel calmer and more comfortable through structured interaction.
Lausanne, Canton of VaudAges 65 years+ - NCT05741853Recruiting
Speech therapy study for bilingual people with primary progressive aphasia
This study looks at how well speech-language therapy works in bilingual people with primary progressive aphasia, a condition that gradually affects language. It also tests whether different language skills (Spanish/Catalan or Spanish/English) affect response to treatment.
Austin, TexasAges 40 years+ - NCT05773443Recruiting
Digital program plus an oral drug for Lewy body dementia
This study tests an eHealth program together with a patient-and-caregiver support program, along with a medicine called ambroxol. It aims to see whether this combined approach is safe and helpful for people with dementia with Lewy bodies (or early memory changes from it).
Haugesund, RogalandAges 50–85 - NCT05779813Recruiting
Family-linked genetic frontotemporal dementia study for teens
This study follows young people ages 9 to 16 who have a close biological family member with genetic frontotemporal dementia (FTD). It aims to better understand this inherited condition and track participants over time. You may complete surveys and thinking/behavior assessments, and you may have brain MRI scans if you choose.
London, OntarioAges 7–17 - NCT05799001Recruiting
Dance workshops for seniors with dementia behavior changes
This trial tests whether structured dance sessions can help improve behavioral and emotional symptoms in people with dementia living in care facilities. It may help by offering a gentle, guided activity while keeping medications stable.
Craponne-sur-ArzonAges 65 years+ - NCT05820919Recruiting
Improve sleep in nursing home residents with dementia
This study aims to improve sleep quality for people in nursing homes who have Alzheimer’s disease or related dementia and are having sleep problems. It uses a sleep-focused approach through staff “sleep huddles” and checks sleep patterns to see what helps.
Lakewood, ColoradoAges 50 years+ - NCT05867641Recruiting
Immersive VR to help dementia caregivers and improve daily life
This study tests whether immersive virtual reality (VR) can help people with dementia feel better and reduce troubling behaviors, while also giving caregivers a break. If you and a family caregiver qualify, you may use VR as part of an at-home support program.
Oakville, OntarioAges 65 years+
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Common questions
- Are there clinical trials for dementia?
- Yes. Clin2 currently lists 492 recruiting dementia studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dementia trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dementia trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.