Clinical trials
Dental clinical trials
Below are recruiting dental clinical trials, each written for real people, not researchers. We’re tracking 489 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03969628Recruiting
Testing two ways to check tooth-caries risk in children
This study compares two different methods of estimating how likely a child is to get tooth decay. If you visit the children’s dental clinic, the researchers will use these methods to help identify risk and plan prevention.
Pelotas, Rio Grande do SulAges 7–11 - NCT04040920Recruiting
Ozone treatment before dental sealants
This trial tests whether applying ozone to certain back teeth before placing sealants helps the sealants work better. You might qualify if you need sealants on specific molars and can safely have the area isolated during treatment.
Trieste, TriesteAges 6–16 - NCT04117360Recruiting
Speech therapy study for people after jaw alignment surgery
This study looks at how well people can make specific speech sounds before and after jaw alignment treatment. It may help researchers understand whether speech patterns improve with treatment in people with certain bite differences.
Chapel Hill, North CarolinaAges 15–40 - NCT04567030Recruiting
AI tool to help improve gum treatment outcomes
This trial tests whether an artificial intelligence (AI) system can help plan and improve results of gum (periodontal) treatment. You may be a good match if you have diagnosed periodontal disease and enough healthy teeth.
Kaohsiung CityAges 35–65 - NCT04605445Recruiting
One vs two dentist visits for infected root canals
This study compares whether treating an infected, dead tooth in one visit works as well as using two visits. It may help you and your dentist choose the simplest schedule while still clearing infection and supporting healing.
Vaxjo, Kronoberg CountyAges 18 years+ - NCT04643951Recruiting
Study of dental students’ and professionals’ child-patient experiences
This study explores how dental students and child-focused dental professionals understand and handle pain in pediatric dentistry. Your experience and perceptions will help researchers describe common challenges and what support works best.
Malmö, Skåne CountyAges 18–65 - NCT04805320Recruiting
Study of gum inflammation after tooth removal
This study looks at how gum (periodontal) inflammation affects the body’s immune response during wound healing after a tooth is taken out. You might be considered because you need a molar or premolar extraction where the tooth cannot be repaired.
Lincoln, NebraskaAges 21–70 - NCT04848870Recruiting
Check dental and gum health in Sjögren’s disease
This study looks at dental and gum (periodontal) health in adults with Sjögren’s syndrome. It may help researchers understand how Sjögren’s affects the mouth and how patients can be supported better.
Ivry-sur-Seine, Île-de-France RegionAges 18 years+ - NCT04880707RecruitingPhase 2
Pain medication options for lower wisdom tooth removal
This study compares pain-medication approaches during and after removing at least one lower impacted wisdom tooth (a tooth that’s stuck). It may help find a safer or more effective way to control dental pain after surgery.
Newark, New JerseyAges 18 years+ - NCT04954664Recruiting
Bone graft particles to help dental implants fit in missing teeth areas
This study tests a bone-grafting approach (using processed donor bone particles, with or without a growth factor) to help dental implants work when the jaw bone is too narrow. It may help people get implants placed more safely and effectively in areas with missing teeth.
Birmingham, AlabamaAges 18–99 - NCT05077618Recruiting
Teeth bacteria study in seniors with and without Alzheimer’s
This study looks at the bacteria in the mouth (periodontal microbiota) to see whether they differ between seniors with Alzheimer’s disease and seniors without it. You may be asked for a sample from your gums/teeth and background health information.
Nice, CHU de NICEAges 18–90 - NCT05188196Recruiting
Collagen sponge vs collagen membrane after tooth removal
This study compares two types of collagen dental materials placed after a back tooth (molar) is removed. The goal is to see which one better helps preserve the jawbone so you can later get a dental implant.
Hangzhou, ZhejiangAges 18–70 - NCT05287763Recruiting
Collagen sponge to help heal palate gum graft wounds
This trial tests whether a collagen sponge can improve healing after a palate-area tissue graft used to repair gum defects. You might benefit if you’re having specific types of gum graft procedures and your mouth health and overall health meet the study rules.
Hangzhou, ZhejiangAges 18–70 - NCT05439330Recruiting
Dental MRI to help diagnose jaw, gum, and tooth problems
This study tests whether a special dental MRI can give useful pictures to diagnose jaw joint problems, tooth-related tissue changes, and gum/inflammation issues, and to help plan some dental implant treatments. If you need imaging for these reasons, the trial may help doctors choose the best next treatment by using clearer, dedicated scans.
AarhusAges 18 years+ - NCT05444127Recruiting
Study of oral health in people with Wilson’s disease
This study compares oral (mouth and teeth) health in people with Wilson’s disease versus people without it. It aims to see whether Wilson’s disease is linked to specific dental and imaging findings, which could help with future prevention and care.
Ivry-sur-SeineAges 18 years+ - NCT05470023Recruiting
Imaging study of gum health and mouth biofilm
This study uses imaging to look at how healthy your gums are and how much “plaque/biofilm” is in your mouth. It may help researchers better understand gum health and how oral hygiene affects it.
Irvine, CaliforniaAges 18 years+ - NCT05581680Recruiting
Facial movement study comparing people with and without facial weakness
This study uses special sensors (electrodes and small markers) to measure how facial muscles move. It compares people with peripheral facial palsy to people without facial problems to better understand facial movement changes.
Amiens, PicardieAges 18 years+ - NCT05637619Recruiting
3D scan study of natural teeth and dental prosthesis wear
This study uses 3D scans to measure how teeth and dental replacements wear against each other over time. It may help improve how dentists design and fit dentures and full-mouth restorations.
LisbonAges 18 years+ - NCT05688982Recruiting
Check oral health needs and local care resources in the ER
This study asks people in the emergency department (and their parents/guardians) about oral health needs and what local resources they can access. It aims to map gaps in dental and oral health support so future care can be better targeted.
Boston, MassachusettsAges 1 year+ - NCT05703789Recruiting
Dental treatment for severe long-term eating disorders
This study focuses on people with severe eating disorders lasting many years and looks at dental needs, since these can lead to extensive tooth damage. You may be eligible if you need significant dental treatment on at least one jaw.
StockholmAges 18–50 - NCT05721781Recruiting
Reducing infection risk after gum and tooth issues
This study looks at ways to lower the risk of infective endocarditis, a serious heart infection that can happen after certain bacteria enter the bloodstream from the mouth. You may be asked to pause routine dental cleanings for a period while they track dental health and infection risk.
Boston, MassachusettsAges 18 years+ - NCT05812053Recruiting
Testing eggshell powder for pulpotomy in baby molars
This trial tests whether applying eggshell powder during a baby tooth pulpotomy (a procedure to treat the nerve tissue) can help heal deep cavities. It may be considered for children whose affected baby molars can be restored and show no signs of infection or bone damage.
Tanta, Gharbia GovernorateAges 4–7 - NCT05838365RecruitingPhase 4
Earlier vs later placement of single tooth implants
This study compares two timing approaches for placing a single implant tooth: putting the implant load (chewing force) on it sooner versus later. It may help show which timing works best for healing and long-term comfort in people with suitable bone and gum tissue.
MilanAges 18–80 - NCT05852145RecruitingPhase 1/Phase 2
Testing sweet drinks effect on children’s mouth health
This early-stage study looks at how drinking soft drinks with and without sweeteners affects children’s mouths and teeth. It may help researchers understand which types of sweet drinks contribute to more tooth damage.
Mexico City, CuahutemocAges 12–18
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Common questions
- Are there clinical trials for dental?
- Yes. Clin2 currently lists 489 recruiting dental studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dental trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dental trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.