Clinical trials
Dental clinical trials
Below are recruiting dental clinical trials, each written for real people, not researchers. We’re tracking 489 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05860712Recruiting
Cinnamon vs chlorine rinse after baby tooth nerve treatment
This trial tests whether a cinnamon extract rinse works as well as a chlorine-based rinse to reduce pain and fight infection after pulpectomy (removing the nerve tissue) in baby teeth. It may help you understand which rinse causes less post-treatment discomfort.
CairoAges 4–8 - NCT05888935Recruiting
AI checks for tooth root infections on dental X-rays
This study tests an artificial intelligence tool to detect small infections around tooth roots using routine panoramic dental X-rays. You might benefit if your scans are used to more accurately spot these problems compared with standard reading.
MetzAges 18 years+ - NCT05965076Recruiting
Test glycine powder and a special brush for oral care
This trial studies whether using glycine powder and an angled implant brush helps keep dental implants healthy in people following the Columbus Bridge ProtocolTM. It may help by improving daily oral hygiene around implants and reducing implant problems.
TorinoAges Any age - NCT05979805Recruiting
Education programs to prevent cavities and gum problems during braces
This study compares two types of education programs to see which better prevents cavities and gum inflammation in people getting braces. Participants must be new to orthodontic treatment and have healthy teeth and gums at the start.
BogotáAges 13–28 - NCT06135714RecruitingPhase 3
Targeting limited breast cancer spread with focused therapy
This trial tests whether treating just the few spots where breast cancer has spread (called oligometastases) with radiation or surgery can help control the disease. It is for people whose cancer has spread to 3 or fewer places, each small in size, and who are healthy enough for local treatments.
Tokyo, TokyoAges 18–80 - NCT06152081Recruiting
Detecting cavities with two new devices
This study tests two different devices for finding cavities in adults at high risk for tooth decay, comparing how well they work against each other and standard methods.
Boston, MassachusettsAges 21 years+ - NCT06172764RecruitingPhase 4
Vitamin D for early cavities: a saliva study
This study tests whether vitamin D supplements can help improve the health of your mouth by looking at changes in saliva and the bacteria that cause cavities. If you have early cavities and low vitamin D, you may be able to join.
Karachi, SindhAges 12–50 - NCT06182293Recruiting
Mouth bacteria in early systemic sclerosis
This study looks at the bacteria in the mouth (periodontal microbiota) of people with early systemic sclerosis compared to those without the condition. It may help understand if there is a link between oral health and systemic sclerosis.
StrasbourgAges 18 years+ - NCT06196515RecruitingPhase 2/Phase 3
Study of a new nano-medication for infected tooth root canals
This trial tests whether a nano-scale calcium hydroxide paste works better than standard treatments for tooth infections. If you have a permanent molar with signs of infection around the root tip, this study may be an option.
CairoAges 21–49 - NCT06207253RecruitingPhase 2/Phase 3
Testing diclofenac gel for tooth root infections
This trial tests whether a special anti-inflammatory gel (diclofenac sodium) placed inside the tooth can help treat an infection at the root tip. It is for adults with a restorable tooth and no allergies to the medication.
CairoAges 18–50 - NCT06252935Recruiting
Collagen membrane for gum and bone repair
This trial tests a new collagen membrane (FormaAid®) for repairing gum and bone damage from gum disease. It may help people with deep gum pockets and bone loss who are not smokers and have well-controlled health conditions.
Taipei, TaiwanAges 18–70 - NCT06315348Recruiting
Gum shaping during braces with a vibration tool
This trial tests a new, less invasive surgical technique (using a special tool that vibrates, not a scalpel) to help reshape the gums while straightening teeth with braces. It is for people who need braces for mild to moderate crowding and have healthy gums.
MadridAges 16–70 - NCT06330207Recruiting
Emergency provider training for dental care
This trial teaches emergency department doctors and advanced providers how to better manage dental emergencies. It aims to improve care for patients with non-traumatic dental problems.
Gainesville, FloridaAges 18 years+ - NCT06357260Recruiting
Adding pregabalin to carbamazepine for trigeminal neuralgia
This trial tests whether adding pregabalin to your usual carbamazepine treatment can better control trigeminal neuralgia pain. It is for people with classic trigeminal neuralgia who want to see if a combination of medicines can help.
Rohtak, HaryanaAges 25–80 - NCT06435208Recruiting
Gum cleaning for mental health in teeth grinders with gum disease
This study tests whether a deep gum cleaning procedure (subgingival instrumentation) can reduce stress and improve mental health in people who grind their teeth and have gum disease. It aims to see if treating the gums can also help with psychological distress.
Rohtak, HaryanaAges 30–50 - NCT06456060RecruitingPhase 1
Honey dressing vs. Alvogyl for dry socket healing
This trial tests whether a pure honey dressing works better than a standard treatment (Alvogyl) for healing dry socket, a painful condition after a tooth extraction. It may offer a natural alternative to help with pain and healing.
Multan Khurd, Punjab ProvinceAges 18–70 - NCT06456827Recruiting
Bite force and bone changes after braces in different face types
This trial compares how bite force and bone turnover markers change during the retention phase (after braces) in people with high-angle and low-angle face types. It may help understand why some people have more relapse after braces.
Rohtak, HaryanaAges 18–45 - NCT06457776Recruiting
Jaw bone health in people taking bone-strengthening drugs
This study looks at how a specific jaw problem (osteonecrosis) may happen in people taking bone-strengthening medications. It aims to better understand and manage this side effect.
RomaAges 18 years+ - NCT06463405Recruiting
Dental implants for missing back teeth: a patient experience study
This study tests how well dental implants work and how they feel for people missing back teeth. You get fixed implant-supported crowns, and the researchers want to understand your experience and how your mouth functions after treatment.
CopenhagenAges 30 years+ - NCT07088679Recruiting
Natural gel for dental implant gum disease
This trial tests a natural gel to treat gum disease around dental implants. It may help reduce bleeding and bone loss around implants.
Pavia, LombardyAges 18–70 - NCT07648212Recruiting
AI Tool for Detecting Tooth Decay in Dental Training
This study tests whether artificial intelligence can help dental students and residents better detect early tooth decay (cavities) between teeth. Participants will learn to use an AI tool and compare it to traditional detection methods to see if it improves accuracy.
Ann Arbor, MichiganAges 18–99 - NCT06505759RecruitingPhase 1
Bromelain gel vs. chlorhexidine for gum disease treatment
This trial tests if a gel made from bromelain (a pineapple enzyme) works as well as a standard antibiotic gel to treat gum pockets caused by periodontitis. It may offer a gentler option for patients with moderate gum disease.
Bengaluru, KarnatakaAges 30–50 - NCT06510244Recruiting
Measuring pain during dental treatment with brain waves
This trial uses EEG (a brain-wave test) and a pain scale to measure how much discomfort you feel during dental treatment on your upper front tooth. It may help dentists understand pain better and improve care.
Cleveland, OhioAges 20–60 - NCT06525285Recruiting
Gum graft techniques for treating severe gum recession
This trial compares two different gum grafting methods to treat advanced gum recession in front teeth. It aims to see if adding a special connective tissue wall helps improve root coverage and gum health.
Bengaluru, KarnatakaAges 18–60
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Common questions
- Are there clinical trials for dental?
- Yes. Clin2 currently lists 489 recruiting dental studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a dental trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a dental trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.