Clinical trials
Depressed clinical trials
Below are recruiting depressed clinical trials, each written for real people, not researchers. We’re tracking 1,509 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06038929Recruiting
Vagus nerve stimulation and stomach function study
This study looks at how vagus nerve stimulation (VNS) affects how your stomach works, like emptying and stretching. It may help researchers understand the digestive side effects of VNS in people who already have a VNS device for epilepsy or depression.
Minneapolis, MinnesotaAges 18 years+ - NCT06038721Recruiting
Unified Protocol for kids with emotional concerns
This trial tests a program called Unified Protocol for children ages 7–17 who have emotional difficulties like anxiety, depression, trauma, or obsessive-compulsive symptoms. It aims to help kids and their parents learn skills to manage these feelings together.
Coral Gables, FloridaAges 7–17 - NCT06045897Recruiting
EEG brain test for young people at risk of psychosis
This study uses a short EEG recording to look at brain activity patterns in young people with early signs of mental health conditions, including those at risk for psychosis, first episode psychosis, depression, or autism. It aims to find brain markers that could help identify people who might benefit from early treatment.
ParisAges 15–30 - NCT06046586Recruiting
Online therapy for cancer survivors with anxiety or depression
This trial tests an online therapy program for cancer survivors who feel anxious, depressed, or worried about cancer coming back. It's a text-based program you can do from home.
StockholmAges 18 years+ - NCT06049420Recruiting
Lifestyle medicine for rural patients with chronic disease
This trial tests whether exercise therapy can help people with two or more chronic conditions like obesity, diabetes, or heart disease. It's designed for rural patients and requires a referral from your doctor.
Lewisburg, West VirginiaAges 18–64 - NCT06060860Recruiting
Comparing two therapies for autistic adults with depression or anxiety
This study compares two types of talk therapy — cognitive-behavioral therapy (CBT) and mindfulness-based therapy — to see which works better for autistic adults who also have depression or anxiety. You would attend online sessions from home.
Chapel Hill, North CarolinaAges 18 years+ - NCT06070766Recruiting
At-home ketamine study for chronic conditions
This trial tests a ketamine protocol you can use at home. It may help if you have a long-term health condition.
Bigfork, MontanaAges 18 years+ - NCT06073886RecruitingPhase 2
Better brain stimulation for long-lasting concussion symptoms
This trial tests whether personalized brain stimulation can help people who have ongoing symptoms more than 20 on a standard concussion scale, such as headaches, dizziness, or trouble concentrating, after a mild head injury in the past year.
Westwood, Los Angeles, CaliforniaAges 18–65 - NCT06075771RecruitingPhase 4
Testing a Parkinson's drug for depression-related loss of interest
This trial tests whether a medication used for Parkinson's disease (carbidopa-levodopa) can help people with major depression who have lost interest or pleasure in things. It is for adults who have not been helped enough by other treatments and have signs of inflammation.
Atlanta, GeorgiaAges 25–55 - NCT06085313Recruiting
Web-based program for cancer pain in Asian women
This trial tests a web-based program to help women of Chinese, Korean, or Japanese heritage manage breast cancer pain and depressive symptoms. If you've had breast cancer, have had pain in the past week, and feel some depression, this program could help you cope better.
Austin, TexasAges 18 years+ - NCT06104696Recruiting
Comprehensive Geriatric Assessment in Kidney Transplant Patients Over 60
This study looks at how a full health review (geriatric assessment) can help older adults who are getting or have gotten a new kidney. It aims to improve care and outcomes for patients aged 60 and over.
PragueAges 60 years+ - NCT06109493Recruiting
Psychological support for kidney dialysis patients
This trial tests a type of talk therapy (ACT) to see if it helps patients on dialysis feel better emotionally. It may be a good fit if you're on dialysis, feeling distressed, and not taking antidepressants.
MadridAges 18 years+ - NCT06116812Recruiting
Laughter yoga and stress reduction for women with breast cancer
This study tests if laughter yoga or mindfulness-based stress reduction helps women with early-stage breast cancer feel less anxious and depressed during chemotherapy. You would join online group sessions from home using your smartphone.
İskenderun, HatayAges 18–60 - NCT06121284RecruitingPhase 2
Brain stimulation plus medication for youth suicide
This study tests if a new type of brain stimulation (iTBS) combined with a medicine called D-cycloserine can reduce suicidal thoughts in young adults who have previously attempted suicide. It aims to find a faster, mood-boosting treatment option for young people at risk.
Calgary, AlbertaAges 18–24 - NCT06123325Recruiting
Mental health and quality of life after unruptured brain aneurysm diagnosis
This trial looks at how being diagnosed with an unruptured brain aneurysm (a weak spot on a blood vessel that hasn't bled) affects your mood, anxiety, and quality of life. It also compares outcomes for people who get treatment (like surgery or a catheter procedure) versus those who are watched with scans.
The Bronx, New YorkAges 18–75 - NCT06136676Recruiting
Comparing spiritual and secular meditation in healthy adults
This study looks at how two kinds of meditation—spiritual (Christian or Muslim) and secular (non-religious)—affect your mind, body, emotions, and social life. If you are a healthy Christian or Muslim adult who prays weekly, this could help researchers understand which type of meditation may work best for people like you.
Calicut, KeralaAges 18–60 - NCT06162741Recruiting
Brief mindfulness training for Veterans in primary care
This study tests whether brief mindfulness training offered in VA primary care can help Veterans with symptoms of PTSD, depression, or anxiety. It aims to see if this approach works well in everyday clinic settings.
Phoenix, ArizonaAges 18 years+ - NCT06175104Recruiting
HeartGPS: Support for parents after a prenatal heart diagnosis
This study tests a counseling program for parents whose unborn baby has a serious heart condition called single ventricle. The program aims to help parents manage stress and support their baby's development before and after birth.
Los Angeles, CaliforniaAges 18 years+ - NCT06178328Recruiting
Online mental health program for Canadian adults
This study is testing a short online mental health program for adults in Canada who are seeking help. It aims to see if the program helps people feel better.
Regina, SaskatchewanAges 18 years+ - NCT06183359Recruiting
Self-Identification Program for Depression
This study tests a self-identification program for people aged 18 to 70 who are currently in a major depressive episode. It aims to explore whether a simple self-monitoring tool can help you better manage your depression.
MontpellierAges 18–70 - NCT06187090Recruiting
Supplement therapy for adults with autism
This trial tests whether a specific supplement can help adults with Level 1 autism. It is open only to Italian-speaking participants aged 18–35 who do not have other major mental health or brain conditions.
Udine, UDAges 18–35 - NCT06197711Recruiting
PRISMA for mental health in pretrial detention
This study tests whether a program called PRISMA can help improve mental health for people in pretrial detention. It is designed for detainees in Zurich and Bern who speak one of nine languages and are not in immediate crisis.
Zurich, Canton of ZurichAges 18 years+ - NCT06200155RecruitingPhase 2
Psilocybin therapy for advanced cancer patients with anxiety or depression
This trial tests whether a drug called psilocybin, given with therapy, can help people with advanced cancer who are feeling anxious or depressed. You must have a stable cancer and be willing to travel to Houston for treatment.
Houston, TexasAges 25 years+ - NCT06205147Recruiting
Elastic band exercise for strength and mood in older hospital patients
This study tests whether using elastic bands for resistance exercises can help older adults in the hospital improve their muscle strength and reduce symptoms of depression. If you are 65 or older, staying in the hospital for more than a week, and able to follow simple instructions, this might be a good fit.
Taipei, TaiwanAges 65 years+
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Common questions
- Are there clinical trials for depressed?
- Yes. Clin2 currently lists 1,509 recruiting depressed studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depressed trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depressed trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.