Clinical trials
Depression and Suicide Ideation clinical trials
Below are recruiting depression and suicide ideation clinical trials, each written for real people, not researchers. We’re tracking 57 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06636357RecruitingPhase 2
Laughing gas for acute suicidal thoughts
This study tests whether breathing a mixture of nitrous oxide (laughing gas) and oxygen can quickly reduce strong suicidal thoughts. It's for people experiencing a mental health crisis who may need fast relief.
ZurichAges 18–65 - NCT06085937RecruitingPhase 1
Ketamine for suicidal patients in the ER
This trial tests if a single dose of ketamine can quickly reduce suicidal thoughts in people who come to the emergency department. If you are having active suicidal thoughts and need inpatient care, you may be able to join.
Kansas City, KansasAges 18–65 - NCT05183230Recruiting
Mobile program to help prevent suicide after hospital stay
This trial tests a phone-based (mobile) support program for middle-aged and older adults after a recent hospital stay for suicidal thoughts or an attempt. The goal is to reduce the chance of another suicidal crisis by providing structured support after discharge.
New York, New YorkAges 50–90 - NCT03646058RecruitingPhase 3
Add-on buprenorphine to ease suicidal thoughts in depression
This Phase 3 study tests whether adding buprenorphine to your usual pain-dose medicines can reduce severe suicidal thoughts during a major depressive episode. It may help people who are currently hospitalized or closely followed and have higher scores for both depression severity and suicidal thinking.
Bordeaux, FranceAges 18–65 - NCT06210100Recruiting
Brain stimulation for self-harm in teens with depression
This study tests a type of brain stimulation (called aiTBS) that uses magnetic pulses to help reduce self-harm and suicidal thoughts in teens with depression. It's for teens who are in the hospital and have been hurting themselves on purpose.
Dali, YunnanAges 12–18 - NCT07063914Recruiting
School-based suicide prevention programs for teens
This trial tests two different support programs for high school students who have been thinking about suicide. Depending on how severe your depression is, you will get one of two online programs to help reduce those thoughts and feel better.
Santiago, Las CondesAges 14–18 - NCT06375083RecruitingPhase 2
Computer therapy for suicide prevention and depression in Veterans
This trial tests two different computer-based therapy programs for Veterans: one for preventing suicide and one for treating depression. Both programs are designed to be done at home on your computer or tablet.
Aurora, ColoradoAges 18–65 - NCT07396220Enrolling by invitation
Psychotherapy with esketamine nasal spray for suicidal thoughts
This study tests combining a specific type of therapy (BCBT-SP) with esketamine nasal spray to help people with treatment-resistant depression who are having ongoing suicidal thoughts. The goal is to see if this combination can reduce suicidal ideation more effectively than either treatment alone.
San Diego, CaliforniaAges 18–70 - NCT06882798Recruiting
New support program for Latinx teens with suicidal thoughts
This study tests a new support program for Latinx teens who have had serious thoughts about suicide or a suicide crisis in the past year. It involves working with both you and your family to find ways to help you feel safer and more supported.
Providence, Rhode IslandAges 12–18 - NCT06009523Recruiting
Testing brain stimulation for suicidal thoughts
This study tests a non-invasive brain stimulation technique called tDCS, which uses mild electrical currents to reduce suicidal thoughts in people with depression. If you have moderate to severe depression and still have suicidal ideation despite treatment, this might be an option.
Faye-l'AbbesseAges 18 years+ - NCT05977439Recruiting
Brain training for depression recovery
This study uses brain imaging and stimulation to help people with depression learn how to regulate their emotions better. It aims to find out if targeting specific brain networks can improve symptoms.
Charleston, South CarolinaAges 18–65 - NCT04923685Recruiting
Study looks at blood markers linked to childhood trauma and suicide risk
This study checks whether tiny genetic signals in blood (microRNAs) are linked to childhood maltreatment and thoughts or risk of suicide, especially in people with major depression. It may help researchers understand biological clues that could someday guide better care.
Birmingham, AlabamaAges 18–60 - NCT07562191RecruitingPhase 2
Inhaled DMT for major depression
This trial tests if inhaling DMT can help treat moderate to severe major depression. You may qualify if your depression has lasted at least two weeks and you have not changed medications recently.
Fortaleza, CearáAges 18 years+ - NCT06651554Recruiting
Suicide prevention app study for teens in Bogota
This trial tests a digital platform designed to help prevent suicide among teenagers. It aims to make mental health support more accessible for students in Bogota schools.
Bogotá, ColombiaAges 14–19 - NCT05377177Recruiting
Brain stimulation type test for suicidal thoughts in depression
This study tests whether stimulating the brain on both sides at once versus one side can reduce suicidal thoughts in people with treatment-resistant depression. It also looks at brain “inhibition” signals to help predict who benefits.
San Diego, CaliforniaAges 18–70 - NCT05437588Recruiting
Blood-based biomarkers for suicide risk in teens with depression
This study looks at tiny blood particles (exosomes) and specific microRNAs to see if they can signal suicide risk and predict treatment outcomes in adolescents. If you qualify, your blood may be used to help researchers find better ways to understand and track suicidality and depression treatment response.
Birmingham, AlabamaAges 10–24 - NCT05925322Recruiting
Social reward therapy for depression-related suicidal thoughts
This study looks at whether “social reward” psychotherapy can change brain activity and reduce suicidal thoughts in adults ages 50–80 who also have major depression. You may be offered psychotherapy along with brain scans to see how your brain responds over time.
New York, New YorkAges 50–80 - NCT06121284RecruitingPhase 2
Brain stimulation plus medication for youth suicide
This study tests if a new type of brain stimulation (iTBS) combined with a medicine called D-cycloserine can reduce suicidal thoughts in young adults who have previously attempted suicide. It aims to find a faster, mood-boosting treatment option for young people at risk.
Calgary, AlbertaAges 18–24 - NCT06804525Recruiting
Adapting a mental health survey in Hong Kong
This study adapts a mental health survey for Hong Kong adults. It is open to adults aged 25 and older who live in randomly selected households and can speak Chinese or English.
Hong KongAges 25 years+ - NCT06891300RecruitingPhase 2/Phase 3
Ketamine for Suicidal Thoughts in Depression
This study tests if ketamine can help reduce suicidal thoughts in people with major depression. You'll receive ketamine treatment and be monitored closely.
Ottawa, OntarioAges 18–65 - NCT07025720Recruiting
Brain stimulation for depression and suicide risk in young people
This study tests a new type of brain stimulation called TMS (transcranial magnetic stimulation) for young people ages 15-25 who are having serious depression and suicidal thoughts. The goal is to see if this treatment can help reduce risk and improve mood.
Sacramento, CaliforniaAges 15–25 - NCT07051200Recruiting
Support program for young adults after a mental health crisis
This study offers a program to support young adults who recently faced a mental health crisis. It aims to help you recover by providing inspiration, support, and empowerment after a hospital stay.
Dallas, TexasAges 18–27 - NCT07170657Recruiting
Teen Recovery Support Program
This program helps teens ages 15 to 18 who have recently been in the hospital or emergency room for suicidal thoughts or depression. It provides support and guidance to help you recover and feel stronger.
Dallas, TexasAges 15–18 - NCT04572321Enrolling by invitation
Teen depression and suicide research study for youth
This study looks at depression and suicidal thoughts or behaviors in children and teens. It may help researchers better understand these risks and improve supports for young people.
Dallas, TexasAges 8–20
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Common questions
- Are there clinical trials for depression and suicide ideation?
- Yes. Clin2 currently lists 57 recruiting depression and suicide ideation studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression and suicide ideation trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression and suicide ideation trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.