Clinical trials
Depression Symptoms clinical trials
Below are recruiting depression symptoms clinical trials, each written for real people, not researchers. We’re tracking 194 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT03794531Recruiting
Study of health, stress, and lifestyle changes in Puerto Rico
This study looks at how people’s health, day-to-day stress, and living conditions in Puerto Rico change over time. You might help researchers understand what trends are happening and what could be improved.
San JuanAges 30–75 - NCT04084795Recruiting
EMDR plus brain stimulation for fibromyalgia pain and stress
This trial tests whether combining EMDR therapy with a mild form of brain stimulation can reduce fibromyalgia symptoms, including pain and trauma-related emotional distress. It may help people whose fibromyalgia is closely linked to past trauma and current anxiety or depression.
Barcelona, CataloniaAges 18–70 - NCT04245436RecruitingPhase 4
Testing antidepressants for teens with anxiety
This trial studies whether an antidepressant can help teens (ages 12–17) with anxiety disorders such as generalized, social, separation, or panic anxiety. It looks at both early and longer-term success of treatment, while monitoring safety closely with a caregiver.
Cincinnati, OhioAges 12–17 - NCT05066308RecruitingPhase 2
Cannabidiol to reduce inflammation in chronic low back pain
This Phase 2 study tests cannabidiol (CBD) to calm inflammation in the brain that may be linked to chronic low back pain. If you qualify, you’ll take study CBD and undergo brain imaging to see whether inflammation changes.
Boston, MassachusettsAges 18–75 - NCT05322343Recruiting
Study biobank and brain health in people age 55–80
This study collects blood samples to build a biobank and learn how brain health changes with age. Some participants may also do an MRI scan to better understand brain changes and immune response.
Bordeaux, BordeauxAges 55–80 - NCT05323864Recruiting
Altitude exposure study for anxiety and low mood
This trial looks at what happens to people with anxiety and depressive symptoms after going to high altitude with low oxygen. It may help researchers understand whether altitude affects these symptoms and how it might be managed.
Innsbruck, TyrolAges 18–65 - NCT05369429Recruiting
Stress and mood support program for adults with cancer
This trial tests a new online “wellbeing guide” to help manage stress and improve quality of life. It focuses on adults with cancer who also have higher-than-usual depressive symptoms.
Chicago, IllinoisAges 18 years+ - NCT05447689Recruiting
Group mind-body skills for anxious graduate students
This trial offers a weekly group program teaching mind-body skills to help reduce anxiety. It’s for graduate students who screen as having moderate or higher anxiety and can attend meetings regularly.
White Plains, New YorkAges 18 years+ - NCT05726721Recruiting
Study of treatment targets for binge eating disorder
This trial studies how binge eating disorder behaves during treatment and compares patterns over time. It may help by improving future treatment approaches for people with binge eating disorder.
Aarhus, Central JutlandAges 18 years+ - NCT05734547Recruiting
Support for children after trauma through parent-and-child sessions
This trial offers a structured program for children who have ongoing trauma symptoms after a scary or harmful event, with work involving both the child and a parent/caregiver. It aims to reduce post-trauma stress symptoms and help the child feel safe again.
AskerAges 7–12 - NCT05752448Recruiting
Care plan support for women after ovarian cancer treatment
This trial looks at survivorship care—how to help women after ovarian cancer treatment. It may improve follow-up planning and support during the first months after treatment ends.
Dallas, TexasAges 18 years+ - NCT05802004Recruiting
Sound stimulation to improve sleep and emotions in young adults
This study tests whether gentle sound stimulation during sleep can improve sleep and how you think and feel in daily life when you have anxiety or depression symptoms. You’ll also do sleep testing in a lab and complete questionnaires to measure changes.
Pittsburgh, PennsylvaniaAges 18–25 - NCT05897021Recruiting
Writing exercises to ease stress for sexual minority veterans
This study tests whether guided “expressive writing” helps reduce distress linked to sexuality-based stress. It targets veterans who have meaningful anxiety or depression symptoms and ongoing stress related to their sexual identity.
Boston, MassachusettsAges 18 years+ - NCT06085313Recruiting
Web-based program for cancer pain in Asian women
This trial tests a web-based program to help women of Chinese, Korean, or Japanese heritage manage breast cancer pain and depressive symptoms. If you've had breast cancer, have had pain in the past week, and feel some depression, this program could help you cope better.
Austin, TexasAges 18 years+ - NCT06187090Recruiting
Supplement therapy for adults with autism
This trial tests whether a specific supplement can help adults with Level 1 autism. It is open only to Italian-speaking participants aged 18–35 who do not have other major mental health or brain conditions.
Udine, UDAges 18–35 - NCT06215235Recruiting
Bright light therapy for depression in intellectual disability
This trial studies how bright light therapy (using a special lamp) is being used to help people with intellectual disabilities who have depression. It involves staff, family members, and patients to see how the therapy works in real life.
RotterdamAges 18 years+ - NCT06586619Recruiting
Tai chi and qigong for older adults with HIV
This study tests whether a remotely taught tai chi and qigong program can improve mood and well-being in people aged 50–75 who are living with HIV. You can join from home using a smartphone.
Miami, FloridaAges 50–75 - NCT06722287Recruiting
Phone support for family caregivers in Thailand
This study tests a mobile program to support the mental health of family caregivers in Thailand. You participate from home using your phone.
BangkokAges 18–80 - NCT06943105Recruiting
Nonviolent communication training for parents with depression or anxiety
This trial tests whether learning nonviolent communication skills can help parents with mild to severe depression or anxiety feel better and improve their relationships with their children. You may be able to join if you're a Hong Kong resident with a child in primary school and you speak Cantonese.
Hong KongAges 24–59 - NCT07024979Recruiting
Music therapy for university students' mental health
This trial tests whether a music therapy program can help university students with moderate stress, social problems, or trouble adjusting to college life. It aims to improve your mental health and well-being.
Hong KongAges 18–35 - NCT07029126Recruiting
Fremanezumab for migraine with depression: caregiver impact study
This trial tests if fremanezumab, a migraine prevention drug, can also reduce the stress and improve the relationship between migraine patients with mild depression and their caregivers. If you or someone you care for has migraines and low mood, this study may help understand how the caregiver is affected.
Rome, ItalyAges 18 years+ - NCT07052110Recruiting
Depression and self-esteem help for teen cancer survivors
This study tests a program called DST to see if it can reduce depression, boost self-esteem, and improve quality of life for teenagers who have finished cancer treatment.
Hong KongAges 13–18 - NCT07165925Recruiting
Music lessons to build resilience in children from low-income families
This study tests whether music training can help build emotional strength in children aged 8-12 from low-income families in Hong Kong. It specifically looks at children who may be at risk for depression or anxiety.
Hong KongAges 8–12 - NCT07228520Recruiting
Pain and strength study for depression and frailty
This trial tests a program to help people with chronic pain, depression, and weakness build strength and coping skills. It may help you if pain limits your daily activities and you feel down or frail.
Baltimore, MarylandAges 50 years+
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Common questions
- Are there clinical trials for depression symptoms?
- Yes. Clin2 currently lists 194 recruiting depression symptoms studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression symptoms trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression symptoms trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.