Clinical trials
Depression clinical trials
A common mood disorder causing persistent sadness and loss of interest. We’re tracking 1,509 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07467473Enrolling by invitation
Brain stimulation study for depression
This trial uses a technique called transcranial magnetic stimulation (a gentle magnetic pulse) to see if activating a specific brain area helps people with depression feel more positive emotions. It involves brain imaging and memory tasks.
Tallahassee, FloridaAges 18–65 - NCT07440355Enrolling by invitation
Light therapy for postpartum depression and baby development
This study looks at how light therapy for mothers with postpartum depression might affect their baby's development. It involves babies born to mothers who are already part of a larger postpartum depression treatment study.
Porto Alegre, Rio Grande do SulAges Any age - NCT07409792Enrolling by invitation
Ear seed therapy for anxiety, sleep, and IVF success
This trial tests if sticking tiny seeds on ear points (auricular therapy) can help women going through IVF feel less anxious, sleep better, and possibly improve their chances of pregnancy. It is for women with infertility who are about to have a frozen embryo transfer and have some anxiety or sleep problems.
Hangzhou, ZhejiangAges 20–45 - NCT07409298Enrolling by invitation
AI support for breast cancer patients on CDK4/6 inhibitors
This trial tests whether an AI-powered management program can improve mental health and daily habits for people with HR+/HER2- breast cancer who are taking CDK4/6 inhibitor pills at home. It is designed to help you feel supported and stay on track with your rehabilitation plan.
TianjinAges 18–80 - NCT07375485Enrolling by invitation
Occupational therapy for brain injury recovery at home
This trial explores how occupational therapy can help people with brain injuries stay engaged in daily life. Researchers want to learn from therapists working in home or community settings to improve care.
Denver, ColoradoAges 18 years+ - NCT07371065Enrolling by invitationPhase 1
Testing a new drug's safety in healthy adults
This trial tests a new medicine called LY03021 in healthy volunteers to see how safe it is, how the body processes it, and if food changes its effects. It's for people who are generally healthy and not taking other medications.
ShanghaiAges 18–45 - NCT07369180Enrolling by invitation
TMS for treatment-resistant depression in adults
This study tests a new type of transcranial magnetic stimulation (TMS) for adults whose depression hasn't gotten better with medication. It compares the real treatment to a sham (inactive) version to see how well it works.
Campbell, CaliforniaAges 22–85 - NCT07362407Enrolling by invitation
Cannabinoid treatment study for patients in Brazil
This study tracks how cannabis-based medicines work in real life. It looks at how people feel and function while using these treatments prescribed by their doctor.
Florianópolis, Santa CatarinaAges 18 years+ - NCT07354334Enrolling by invitation
Listening to a Quranic surah after cesarean birth
This study tests if listening to Surah Al-Inshirah after a cesarean helps new mothers feel better. It looks at things like pain, anxiety, and recovery.
Konya, SelçukluAges 18–45 - NCT07347158Enrolling by invitation
Health education for ostomy patients
This study teaches people with an ostomy (a surgical opening for waste) about their health to improve their quality of life and reduce anxiety or depression. If you are an adult with a permanent or long-term ostomy and live in the Santiago or Barbanza area, you may be able to join.
Santiago de Compostela, A CoruñaAges 18 years+ - NCT07345858Enrolling by invitation
Saliva test for psychedelic depression treatment
This trial tests whether a simple saliva test can measure oxytocin levels during a psychedelic treatment for hard-to-treat depression. The goal is to find a biological marker that helps predict how well the therapy works.
GenevaAges 18 years+ - NCT07345377Enrolling by invitation
Personalized brain stimulation for irritable bowel syndrome
This study uses brain stimulation (TMS) customized for each person to treat IBS. It uses MRI scans to see how the brain responds, aiming to find better ways to predict who will benefit from this therapy.
Hangzhou, ZhejiangAges 18–75 - NCT07314190Enrolling by invitation
Blood tests for brain diseases and mental health conditions
This study looks at blood tests to help diagnose and track brain diseases (like Alzheimer's) or mental health conditions. It compares patients to healthy volunteers to find better ways to detect and monitor these illnesses.
BarcelonaAges 18 years+ - NCT07259109Enrolling by invitation
Understanding mental health in teens
This study looks at how mental health conditions affect teenagers aged 12 to 20. It may help doctors better understand and support teens with these challenges.
Messina, ItalyAges 12–20 - NCT07239843Enrolling by invitation
Study of blood markers and mental health in brain diseases
This study looks at how social factors and blood markers relate to psychiatric symptoms in people with brain diseases or mental disorders. It aims to find new ways to understand and diagnose these conditions.
Barcelona, BarcelonaAges 18 years+ - NCT07234851Enrolling by invitation
Brain tissue study of synaptic loss in mental and brain diseases
This study looks at how brain connections break down in people with psychiatric disorders (like schizophrenia, depression, or bipolar disorder) or neurodegenerative diseases (like Alzheimer's or frontotemporal dementia). It uses donated brain tissue after death to understand why symptoms occur.
BarcelonaAges 40 years+ - NCT07217197Enrolling by invitation
A monitor to detect breathing problems after surgery
This trial tests a new respiratory monitoring system to see if it can detect and predict opioid-induced respiratory depression (OIRD) — when pain medicines slow your breathing too much — in patients recovering from surgery. The monitor uses a face mask, nasal cannula, and small sensors to track breathing continuously, so that doctors can step in early if there is a problem.
Philadelphia, PennsylvaniaAges 18 years+ - NCT07216638Enrolling by invitation
Better mental health care for kids in primary care
This trial studies how to better integrate mental health care into pediatric primary care clinics across Indiana. It involves surveys, interviews, and looking at patient records to understand and improve care for children.
Indianapolis, IndianaAges 5 years+ - NCT07198542Enrolling by invitation
Vagus nerve stimulation for somatic symptom disorder
This trial tests if gentle electrical stimulation on the vagus nerve in the ear or neck can help reduce physical symptoms that are closely linked to stress. It is for adults with somatic symptom disorder who are on stable medications.
Douliu, YunlinAges 18–65 - NCT07000799Enrolling by invitation
School absence and well-being study for elementary kids
This study tests a group program to help children who struggle with school attendance due to anxiety or sadness. It aims to boost well-being and reduce school avoidance.
OsloAges 8–13 - NCT06885138Enrolling by invitation
Testing brain stimulation for depression in Parkinson's disease
This trial tests if a gentle brain stimulation technique called tDCS can improve depression symptoms in people with Parkinson's disease. You'll receive either real or placebo stimulation over several sessions to see if it helps your mood.
MilanAges 35–75 - NCT06881758Enrolling by invitation
High intensity training for anxiety treatment
This study tests whether high intensity exercise can help reduce anxiety symptoms. It is for adults with mild to moderate anxiety disorders who are physically able to exercise.
TromsøAges 18–65 - NCT06880796Enrolling by invitation
Mindfulness therapy for serious mental illness
This trial tests whether mindfulness-based therapy helps people with serious mental illnesses like schizophrenia or mood disorders. You'll learn mindfulness skills in a group setting at your community mental health center.
Providence, Rhode IslandAges 18 years+ - NCT06823024Enrolling by invitation
Using speech patterns to predict treatment response in depression, PTSD, or bipolar disorder
This study tests if a computer algorithm can analyze your speech to predict how well you will respond to treatments like TMS or Spravato. It aims to create a simple tool that helps doctors choose the right treatment for you.
Sunnyvale, CaliforniaAges 18–68
Hear when a new Depression trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for depression?
- Yes. Clin2 currently lists 1,509 recruiting depression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.