Clinical trials
Depression clinical trials
A common mood disorder causing persistent sadness and loss of interest. We’re tracking 1,507 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07528014Recruiting
Tracking Depression Treatment Outcomes Over Time
This study follows adults receiving depression treatment (esketamine, TMS, or SAINT) to understand how these therapies work and their effects over time. Researchers will assess mood, functioning, and other factors to help improve future treatment.
La Jolla, CaliforniaAges 18 years+ - NCT07538427Recruiting
Music Therapy for Health in Rural Elder Care
This study explores whether music can improve health and wellbeing in older adults living in rural care facilities. Researchers will work with residents to understand how music might help with mood, memory, and quality of life.
Flagstaff, ArizonaAges Any age - NCT07544563Recruiting
Brain Activity During Sound Testing
This study measures how your brain responds to sounds in a specially designed quiet room. Researchers want to understand how epilepsy affects sound processing, which could help improve treatment in the future.
ParisAges 18 years+ - NCT07556692Recruiting
Home Brain Stimulation for Bipolar Depression
This study tests whether a device you use at home can help reduce depression symptoms in people with bipolar disorder. The device uses gentle electrical stimulation on the scalp to potentially improve mood.
LondonAges 18 years+ - NCT07561632Recruiting
Early Stress Screening After Emergency Cesarean Delivery
This study looks at whether certain signs of distress right after an unexpected cesarean delivery can predict who might develop PTSD (post-traumatic stress disorder) later. Researchers want to understand this connection so they can help women who are struggling after this traumatic birth experience.
Vancouver, British ColumbiaAges 19 years+ - NCT07571226Recruiting
Urban Stress and Mental Health Monitoring Study
This study explores how city living and daily stress affect depression, anxiety, and alcohol use disorders by having you wear a monitoring wristband and use a smartphone app to track your physical responses. Researchers hope to better understand the link between environmental stress and mental health symptoms.
BeijingAges 18–60 - NCT07591363Recruiting
Building Emotional Intelligence Skills for Students and Teachers
This study teaches secondary school students and teachers in Dhaka how to better understand and manage their emotions. It focuses on students who may struggle with emotional awareness and aims to improve their mental health through an emotional intelligence training program.
DhakaAges 12–17 - NCT07600411Recruiting
Weight-loss surgery and mood: comparing two surgical approaches
This study follows patients undergoing one of two common weight-loss surgeries (sleeve gastrectomy or gastric bypass) to see how each affects binge eating, depression, and anxiety. Researchers want to understand which surgery may help improve both weight and mental health outcomes.
Cairo, Al-Manial CairoAges 18–60 - NCT07604389Recruiting
Augmented Reality Video for Breast Cancer Recovery
This study tests whether an interactive video using augmented reality (a technology that overlays digital information on the real world) helps breast cancer patients recover better after surgery. Researchers want to see if this educational tool improves your understanding of your condition and recovery process.
Taichung, Taichung CityAges 18 years+ - NCT07604753Recruiting
Comparing two mental health screening questionnaires
This study compares two different questionnaires that doctors use to diagnose mental health conditions. Researchers want to check if a newer, shorter questionnaire works just as well as the longer standard one.
Hong KongAges 18 years+ - NCT07631845Recruiting
Music and breathing exercises to improve mood and resilience in older adults
This study tests whether combining music with breathing exercises can help older adults manage anxiety and depression. You'll learn techniques that may improve your emotional well-being and resilience.
Hong KongAges 65 years+ - NCT07633626Recruiting
Vortioxetine for thinking problems from ALK lung cancer treatment
This trial tests whether a medication called vortioxetine can help improve memory, focus, and thinking problems caused by lorlatinib, a drug used to treat ALK-positive lung cancer. You would take vortioxetine alongside your current cancer treatment to see if it helps your brain function.
BogotáAges 18 years+ - NCT07637799Recruiting
Parent support group for teens with autism and anxiety or depression
This study tests whether a parent support group helps families manage anxiety or depression in teenagers who have autism. The group teaches parents skills to support their teen at home.
GothenburgAges 12 years+ - NCT07656623Recruiting
Probiotics for IBS with stomach issues and stress
This trial tests whether a special probiotic blend can help people with irritable bowel syndrome (IBS) who also have stomach symptoms like heartburn, bloating, or nausea, and feel anxious, depressed, or stressed. It aims to see if the probiotic improves both gut and mood symptoms.
Hanoi, HanoiAges 18 years+ - NCT07590115Enrolling by invitation
Behavioral Patterns and Treatment Success in Substance Use Recovery
This study looks at how behavioral patterns change during residential treatment for substance use disorder. Researchers will track your progress over several weeks to understand what helps people succeed in recovery.
Potrerillos, JaliscoAges 18–60 - NCT07561515Enrolling by invitation
Sound Therapy for Anxiety, Stress, and Depression
This study tests whether listening to specially designed sound can help reduce anxiety, stress, or depression. You'll participate for 3 weeks and answer questionnaires about how you feel.
Belo Horizonte, Minas GeraisAges 18 years+ - NCT07560241Enrolling by invitation
Art Therapy to Help Nursing Students With Stress and Mood
This study tests whether an art therapy program can help nursing students manage depression, anxiety, and stress. You'll participate in art therapy sessions and complete surveys about your mood and emotional skills.
Istanbul, IstanbulAges 17–23 - NCT07558785Enrolling by invitation
Testing speech and memory checks at home for early thinking problems
This study uses a video-based system at home to check your speech and memory, helping doctors spot thinking problems early using artificial intelligence. The goal is to see if this simple, at-home test can reliably catch early memory and thinking changes.
PilsenAges 40 years+ - NCT07550166Enrolling by invitation
Mindfulness App Study for Korean Older Adults
This study tests whether a mindfulness app—guided exercises to help you relax and focus your mind—can improve wellbeing in Korean immigrants aged 60 and older. You'll use the app on your smartphone for 8 weeks.
Tampa, FloridaAges 60 years+ - NCT07511660Enrolling by invitation
Ovarian cell injection for perimenopause symptom relief
This trial tests injecting special cells called Muse cells into the ovaries to help relieve perimenopause symptoms and possibly restore ovarian function. It may help women experiencing irregular periods, hot flashes, sleep problems, mood changes, or trouble thinking clearly.
Monterrey, Nuevo LeónAges 28–70 - NCT07499219Enrolling by invitation
Digital help for students waiting for mental health support
This study tests a short digital program for students who are on a waiting list for psychological treatment. It aims to see if the program can provide support while they wait.
Oslo, OsloAges 18–80 - NCT07483034Enrolling by invitation
Music therapy for anxiety during breast cancer treatment
This study tests whether listening to specially chosen music while you're in the hospital for breast cancer treatment can help lower anxiety and depression. It also looks at how music might affect certain substances in your blood that are linked to stress and healing.
Zagreb, City of ZagrebAges 18–65 - NCT07467473Enrolling by invitation
Brain stimulation study for depression
This trial uses a technique called transcranial magnetic stimulation (a gentle magnetic pulse) to see if activating a specific brain area helps people with depression feel more positive emotions. It involves brain imaging and memory tasks.
Tallahassee, FloridaAges 18–65 - NCT07440355Enrolling by invitation
Light therapy for postpartum depression and baby development
This study looks at how light therapy for mothers with postpartum depression might affect their baby's development. It involves babies born to mothers who are already part of a larger postpartum depression treatment study.
Porto Alegre, Rio Grande do SulAges Any age
Hear when a new Depression trial opens
We’ll email you when one opens — at most once a week, no account needed, unsubscribe anytime.
Common questions
- Are there clinical trials for depression?
- Yes. Clin2 currently lists 1,507 recruiting depression studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a depression trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a depression trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.