Clinical trials
Disability or Chronic Disease Leading to Disablement clinical trials
Below are recruiting disability or chronic disease leading to disablement clinical trials, each written for real people, not researchers. We’re tracking 686 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07302048Recruiting
Mobile pain management support for kids with intellectual disabilities
This study tests a mobile program that helps manage pain in children and young adults with intellectual disabilities, autism, or multiple disabilities. It aims to see if the program improves pain relief and works well with their care team.
BrestAges Up to 24 years - NCT06884046Recruiting
Supporting parents of babies with heart conditions
This study offers support to parents whose baby is diagnosed with a heart condition before birth and will need surgery shortly after birth. The goal is to help parents manage stress during this difficult time.
Pessac, FranceAges birth–4 weeks - NCT07282704Recruiting
Falls study for people with intellectual disabilities
This study looks at what makes people with intellectual disabilities more likely to fall. It aims to create a way to predict falls, which can help prevent them and keep you safer.
Betanzos, A CoruñaAges 18 years+ - NCT07275736RecruitingEarly Phase 1
CAR-T cell therapy for autoimmune diseases
This trial tests a treatment called CNCT19, a type of CAR-T cell therapy, for people with certain autoimmune diseases like neuromyelitis optica, myasthenia gravis, or multiple sclerosis that have come back or not responded to other treatments. It aims to see if targeting a specific immune cell (CD19) can help control the disease.
BeijingAges 18–75 - NCT07278544Recruiting
Communication preference study for challenging behavior
This study looks at how people with intellectual or developmental disabilities communicate and how their communication preferences can help reduce challenging behaviors. It may help find better ways to support those who do not use spoken language.
Athens, GeorgiaAges 2–90 - NCT07241195Recruiting
Fatty Liver Study in Older Adults
This study follows older adults with fatty liver disease to understand how their metabolism changes over time and how it affects their overall health. It helps researchers learn more about the condition and its impact on the body outside the liver.
Hangzhou, ZhejiangAges 65–100 - NCT07223437Recruiting
Restricted exercise for peripheral artery disease study
This study tests a new type of exercise that uses a blood-flow restriction cuff to see if it helps people with leg pain from blocked arteries. If you have stable claudication (leg pain when walking) and have been referred to cardiac rehab, you may qualify.
Knoxville, TennesseeAges 18 years+ - NCT07223008Recruiting
Bilateral artery embolization for chronic migraine
This trial tests a procedure called bilateral middle meningeal artery embolization to see if it reduces chronic migraine symptoms in people who haven't found relief from other treatments. It's for those with frequent, disabling migraines that affect both sides of the head.
Baltimore, MarylandAges 18–80 - NCT07214844Recruiting
Freezing vs. heating nerves for chronic low back pain
This study compares two procedures to treat long-term low back pain from the small joints in your spine. One uses extreme cold, the other uses heat to stop pain signals. It may help if you have had at least three months of back pain and other treatments haven't worked.
The Bronx, New YorkAges 18 years+ - NCT07220746Recruiting
Math learning study for first graders
This study looks at how math skills and thinking skills affect each other in first graders with math learning difficulties. If your child is in a participating school and scores below certain levels on math and memory tests, they may be able to join.
Nashville, TennesseeAges 6–8 - NCT07220590Recruiting
Power wheelchair training for toddlers with cerebral palsy
This study tests whether giving young children with cerebral palsy a powered wheelchair or similar device at a young age can help them explore and learn. Parents, therapists, and children work together at home and in early childhood settings.
Hillsboro, OregonAges 1 year+ - NCT06161805RecruitingPhase 3
Esketamine for chronic pain from endometriosis
This trial tests if esketamine, a nasal spray, can reduce chronic pelvic pain in women with endometriosis that hasn't improved with standard painkillers. You may qualify if you have severe pain and are scheduled for endometriosis surgery.
DelftAges 18–50 - NCT05792852Recruiting
Help for disabled people facing social participation challenges
This study aims to improve how supported people with disabilities from underrepresented groups can take part in social activities after COVID. You may be invited if you have trouble with social participation and can communicate your interest.
Chicago, IllinoisAges 18 years+ - NCT05971329Recruiting
Pilot study of bone graft for cervical disc wear and nerve symptoms
This trial tests a new bone graft product (ZetaFuse™) used during front-of-the-neck surgery to treat “wear and tear” in the cervical (neck) discs causing nerve problems. It may help relieve pain and nerve-related symptoms when other treatments haven’t worked.
Randwick, New South WalesAges 22–75 - NCT06944730Recruiting
Trunk muscle training for better movement and balance in low back pain
This study tests whether trunk muscle training can improve the quality of your movements and balance if you have chronic low back pain. It is designed for people with moderate pain and no other major health issues.
Hong KongAges 18–55 - NCT06932432Recruiting
Psychological support study for young adults with chronic pain
This study tests a new approach to psychological support for young adults (ages 18-25) with chronic pain that started in childhood. It uses daily surveys on your smartphone to adjust support based on what you need day to day.
Seattle, WashingtonAges 18–25 - NCT07166757RecruitingPhase 1/Phase 2
Study of XS411 for early-onset Parkinson's disease
This trial tests a new treatment called XS411 for people with early-onset Parkinson's disease (age 50 or younger at diagnosis). It is for those whose motor symptoms are not well controlled with standard medications and who may benefit from a neurosurgical procedure.
Shanghai, Shanghai MunicipalityAges 18–70 - NCT05395624RecruitingPhase 1/Phase 2
Safety imaging study of a PET tracer in ALS, Alzheimer, MS, Parkinson
This early-phase study tests the safety of a radioactive tracer (“18F-OP-801”) and how the tracer moves through the body (biodistribution) in people with ALS, Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, and in healthy volunteers. It also measures how the body processes the tracer (“pharmacokinetics”) to support future studies.
San Francisco, CaliforniaAges 18–80 - NCT07157735RecruitingPhase 2
Testing an anti-inflammatory drug for early Parkinson's disease
This trial tests whether the anti-inflammatory drug dapansutrile can help people with early Parkinson's disease. You would get either dapansutrile or a placebo (a pill with no active drug) to see if it slows the disease.
CambridgeAges 50–80 - NCT07152197Recruiting
Resistance Exercise for Charcot-Marie-Tooth Disease
This trial tests whether resistance exercises (like lifting weights with your legs) can help people with Charcot-Marie-Tooth disease. It is for young adults aged 15 to 29 who can move their ankle enough to do strength training.
Temuco, La AraucaníaAges 15–29 - NCT06732180RecruitingPhase 1
Testing a new drug (GT-02287) for Parkinson's disease
This trial tests an investigational drug called GT-02287 in people with early-stage Parkinson's disease (diagnosed within the last 7 years). The goal is to see if it is safe and how the body processes it, with a special focus on people with certain genetic changes (GBA1 mutations) that may be linked to Parkinson's.
Darlinghurst, New South WalesAges 30–85 - NCT07118293Enrolling by invitation
Sensory therapy program for kids with developmental disabilities
This study tests a family-focused therapy program that uses calming sensory activities to help children with developmental disabilities engage better and feel more empowered. It also supports parents by giving them tools and confidence.
TainanAges 3–12 - NCT07101523Recruiting
Using technology to promote healthy lifestyles
This trial uses technology to help adolescents with intellectual disabilities adopt healthier habits like exercise and good nutrition. It aims to find out if using smartphones can make it easier to stay active and eat well.
Seville, SpainAges 4–30 - NCT07092995Enrolling by invitation
Understanding freezing of gait in Parkinson's using VR and brain signals
This study uses virtual reality and brain recordings from your DBS device to understand why some people with Parkinson's experience freezing of gait (feeling like your feet are stuck to the ground). You'll be asked to walk in a safe VR environment while researchers monitor your brain activity.
Los Angeles, CaliforniaAges 18 years+
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Common questions
- Are there clinical trials for disability or chronic disease leading to disablement?
- Yes. Clin2 currently lists 686 recruiting disability or chronic disease leading to disablement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disability or chronic disease leading to disablement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disability or chronic disease leading to disablement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.