Clinical trials
Disability or Chronic Disease Leading to Disablement clinical trials
Below are recruiting disability or chronic disease leading to disablement clinical trials, each written for real people, not researchers. We’re tracking 687 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT05285683RecruitingPhase 2
Study brain dopamine in people with chronic pain
This Phase 2 study looks at how a brain chemical called dopamine is involved in long-lasting pain. You may be able to join if you have chronic pain for over a year and your pain score is high enough, and if MRI and health checks are safe for you.
Rochester, New YorkAges 18 years+ - NCT05304286Recruiting
Study of brain and pain in long-lasting post-surgery pain
This trial studies what’s happening in the brain and how pain is processed in people with pain that lasts long after surgery. It may help researchers understand chronic post-surgical pain and find better ways to treat it.
Boston, MassachusettsAges 12 years+ - NCT05337033RecruitingPhase 2
Testing cannabis for chronic headaches in teens
This trial studies whether cannabis can reduce chronic migraine headaches in adolescents who have not improved with other treatments. It also asks participants to work with psychology and physiotherapy during the study.
Vancouver, British ColumbiaAges 14–17 - NCT05395624RecruitingPhase 1/Phase 2
Safety imaging study of a PET tracer in ALS, Alzheimer, MS, Parkinson
This early-phase study tests the safety of a radioactive tracer (“18F-OP-801”) and how the tracer moves through the body (biodistribution) in people with ALS, Alzheimer’s disease, multiple sclerosis, Parkinson’s disease, and in healthy volunteers. It also measures how the body processes the tracer (“pharmacokinetics”) to support future studies.
San Francisco, CaliforniaAges 18–80 - NCT05404581Recruiting
Insula brain stimulation for long-term nerve pain
This trial tests whether stimulating a specific brain area (the insula) can reduce chronic nerve pain. It is for people whose pain has lasted at least 6 months and has not improved enough with several pain medicines and other procedures.
Charlottesville, VirginiaAges 18–80 - NCT05417737Recruiting
Ozone therapy for chronic pain when standard treatments fail
This study offers a palliative (comfort-focused) ozone treatment to adults with chronic pain when usual treatments don’t work or are too risky. Researchers will check whether adding ozone can help symptoms and whether it’s safe for selected patients.
Las Palmas, Las PalmasAges 18 years+ - NCT05473429Recruiting
Study how pain works in people with intellectual disability
This study measures how you feel pain (nociception) and compares patterns in people with intellectual disability and healthy volunteers. It may help researchers better understand pain differences and improve future pain care.
Bethesda, MarylandAges 8–30 - NCT05632432Recruiting
Heart tissue grafts to help the heart after surgery
This trial tests whether transplanting tiny heart “micrografts” from the left heart chamber area can improve heart function after cardiac surgery. It is meant for people with weakened heart pumping and heart failure symptoms despite medicine.
Helsinki, UusimaaAges 18–75 - NCT05716321Recruiting
Study of pain and function after limb amputation surgery
This study looks at pain and day-to-day functioning after someone has a limb removed due to surgery. The results may help doctors better understand what to expect and how to improve comfort and mobility after amputation.
Hershey, PennsylvaniaAges 18–89 - NCT05726331Recruiting
Tai chi and chiropractic for long-term neck pain
This trial looks at whether a program of tai chi and chiropractic care can improve chronic, non-specific neck pain and daily function. It may help people who have had neck pain for months and want a structured exercise-and-care approach.
Chestnut Hill, MassachusettsAges 18–65 - NCT05733702Recruiting
Study of Crohn’s and ulcerative colitis treatment changes
This study follows adults with Crohn’s disease or ulcerative colitis when their treatment is changed. It collects health information and samples to better understand how treatment changes affect people over time.
LuxembourgAges 18 years+ - NCT05749419Recruiting
Vaccines for children with disabilities and long-term conditions
This study looks at how vaccines work in children who have disabilities, long-term (chronic) illnesses, or conditions they were born with. It may help improve vaccine care for kids who need extra support.
JerusalemAges Any age - NCT05767203Recruiting
Study genetic and blood markers in people with inherited intellectual disability
This study looks at genetic-related and blood/biologic markers in people with an inherited (genetic) intellectual disability. The goal is to better understand these differences and how they might relate to the condition.
ParisAges Any age - NCT05792852Recruiting
Help for disabled people facing social participation challenges
This study aims to improve how supported people with disabilities from underrepresented groups can take part in social activities after COVID. You may be invited if you have trouble with social participation and can communicate your interest.
Chicago, IllinoisAges 18 years+ - NCT05808478Recruiting
Eye-tracking tool for kids who cannot speak well
This trial tests an eye-tracking technology that lets children communicate by using where they look on a screen. It may help children with severe communication needs do tasks and use simple functions without needing speech or hand control.
MessinaAges 3–17 - NCT05833087Recruiting
Schema therapy for long-lasting, hard-to-treat depression
This study tests whether schema therapy can help people with chronic depression that hasn’t improved enough with standard antidepressant treatments. You’d be in a psychiatric clinic and be assessed for severity and diagnosis, then receive the therapy being studied.
Ballerup MunicipalityAges 18–65 - NCT05851508RecruitingPhase 3
Steroid ear injections for vertigo in one-ear Ménière’s
This Phase 3 study compares injections of steroid medicine into the ear versus a dummy (placebo) injection to see if it reduces vertigo attacks in people with Ménière’s disease. It may help by improving balance symptoms and reducing how often attacks happen.
Leiden, South HollandAges 18–100 - NCT05971329Recruiting
Pilot study of bone graft for cervical disc wear and nerve symptoms
This trial tests a new bone graft product (ZetaFuse™) used during front-of-the-neck surgery to treat “wear and tear” in the cervical (neck) discs causing nerve problems. It may help relieve pain and nerve-related symptoms when other treatments haven’t worked.
Randwick, New South WalesAges 22–75 - NCT05986643Recruiting
Brain training game to improve balance in Parkinson's
This trial tests a brain-training game designed to improve balance in people with Parkinson's disease. You may be eligible if you have mild to moderate Parkinson's, have had a fall and freezing episodes in the past year, and are not very active.
LeicesterAges Any age - NCT06002581Recruiting
Using brain stimulation to slow Parkinson's disease progression
This study tests if a non-invasive brain stimulation technique called rTMS (repetitive Transcranial Magnetic Stimulation) can slow down Parkinson's disease by improving slow-wave sleep. It aims to help people with mild to moderate Parkinson's who are stable on their medication.
Shanghai, Shanghai MunicipalityAges 50–80 - NCT06008704Recruiting
PET scan study of pain in Parkinson's disease
This study uses a special brain scan (PET) to look at the serotonin system in people with Parkinson's who have chronic pain. The goal is to understand why some people feel pain and how the brain chemical serotonin might be involved.
Toulouse, Haute-GaronneAges 40–80 - NCT06032455Recruiting
Family therapy for teens with behavior problems and intellectual disabilities
This study tests whether a therapy called Multisystemic Therapy (MST) helps teens with behavior problems who also have a family member with an intellectual disability. The therapy works with the whole family to keep the teen at home and improve behavior.
HalsterenAges 10–19 - NCT06065527Recruiting
Future planning for caregivers of people with disabilities
This study helps family caregivers plan for the future and improve their well-being while caring for a loved one with an intellectual disability. It's done online or on a device, so you can take part from home.
New Hyde Park, New YorkAges 18 years+ - NCT06070467Recruiting
Understanding daily life of children with rare eye disease
This study looks at how children with rare eye diseases experience their daily lives. It aims to understand their real-life challenges and feelings through interviews and questionnaires.
StrasbourgAges 8 years+
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Common questions
- Are there clinical trials for disability or chronic disease leading to disablement?
- Yes. Clin2 currently lists 687 recruiting disability or chronic disease leading to disablement studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a disability or chronic disease leading to disablement trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a disability or chronic disease leading to disablement trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.