Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,196 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07309601Recruiting
Sucrase-isomaltase genes and meal study for IBS
This study looks at how people with irritable bowel syndrome (IBS) handle meals based on their genes for an enzyme that breaks down sugar and starch. It may help explain why some people benefit from a starch- and sugar-reduced diet.
Malmö, Skåne CountyAges 18–70 - NCT07312409Recruiting
Taurine for long COVID vascular health
This study tests whether taking taurine supplements can improve blood vessel function and help with dizziness or fainting caused by long COVID.
Toronto, OntarioAges 18–65 - NCT07313644Recruiting
Finding best breathing support for lung injury after trauma or surgery
This study tests a way to set breathing machine pressures using electrical imaging of the lungs. It aims to find the best settings for patients with lung injury after trauma or major surgery, helping them breathe better with less damage.
HanoiAges 18–90 - NCT07315386Recruiting
Study of catatonic syndrome in adults at Basurto Hospital
This study looks at how often catatonic syndrome occurs in adults treated at Basurto Hospital, what other conditions it's linked to, and what happens in the short term. It helps doctors better understand this serious condition.
Bilbao, VizcayaAges 18 years+ - NCT07316413Recruiting
Repetitive TMS for frontotemporal degeneration
This trial tests whether repetitive transcranial magnetic stimulation (rTMS) can help people with frontotemporal lobar degeneration. It is a non-invasive brain stimulation technique that may improve symptoms.
Brescia, ItalyAges 18 years+ - NCT07316894Recruiting
Consensus on IWS diagnosis for ICU doctors
This trial asks specialists in intensive care, anesthesia, or psychiatry to help create a shared definition for a condition called IWS. It may help improve how we recognize and treat patients.
BucharestAges Any age - NCT07317076Recruiting
Magnetic device study for stomach and bowel blockages
This trial tests a new magnetic device that creates a connection between parts of your stomach or small intestine without needing stitches, for people with certain blockages or digestive issues.
Westmount, QuebecAges 18 years+ - NCT07321626RecruitingPhase 1
Romiplostim for platelet recovery after stem cell transplant
This trial tests if romiplostim, a drug that helps the body make platelets, can speed up platelet recovery after a special type of stem cell transplant from a half-matched donor. It may help reduce bleeding risk during the recovery period.
HangzhouAges 18 years+ - NCT07325110Recruiting
Teens with chronic pain: yoga in occupational therapy
This study looks at whether adding yoga to occupational therapy helps teens with chronic pain better understand their body's signals. It aims to improve daily function and well-being.
Hartford, ConnecticutAges 11–21 - NCT07326111RecruitingPhase 4
Tirzepatide for PCOS and weight in women
This study tests if tirzepatide (a once-weekly injection) can improve periods and metabolic health in women with PCOS who are overweight. If you have PCOS, irregular cycles, and a BMI of 27 or higher, you might qualify.
BochumAges 18–45 - NCT07326215Recruiting
A study of a device that removes carbon dioxide from the blood
This trial tests a device called PrismaLung+ that helps remove extra carbon dioxide from the blood of patients on breathing machines. It may help people whose lungs are struggling despite gentle ventilation settings.
Beijing, Beijing MunicipalityAges 18 years+ - NCT07327684Recruiting
Imaging brown fat activity with ultrasound
This study uses a special camera (photoacoustic/ultrasound) to look at a type of fat called 'brown fat' that helps your body burn energy. You may be able to join as a healthy volunteer or if you have a condition like type 2 diabetes or PCOS.
BeijingAges 18–80 - NCT07327775Recruiting
ADHD and fibromyalgia in mothers
This study looks at how having fibromyalgia affects mothers who also have a child with ADHD. It compares them to mothers of children without ADHD to see if the burden of care is different.
EdirneAges 18–50 - NCT07329257Recruiting
Project PENGUIN: Study of rare brain development disorders
This study looks at rare and ultra-rare conditions that affect brain development. It aims to learn more about what causes these conditions. You may join if you or your child have a diagnosed or suspected neurogenetic disorder.
Columbia, MissouriAges Up to 99 years - NCT07334444Recruiting
Improving sleep apnea care for children with Down syndrome
This study looks at how sleep apnea is managed in children with Down syndrome. It aims to find better treatment approaches by reviewing data from kids who visited ear, nose, and throat (ENT) or sleep specialists in Strasbourg.
StrasbourgAges birth–17 years - NCT07336394Recruiting
Study on rare heart muscle diseases using advanced MRI
This study uses a special heart MRI to better diagnose and understand rare heart muscle diseases. It may help doctors predict risks and make more accurate treatment decisions.
BeijingAges Any age - NCT07336797RecruitingPhase 2
Empagliflozin for weight and metabolism in HIV
This trial tests if empagliflozin, a diabetes medicine, can improve weight and metabolism in people with HIV who take dolutegravir and have a high body mass index (BMI). It may help reduce weight gain linked to HIV treatment.
CairoAges 18–65 - NCT07338929Recruiting
Physical performance test for kidney transplant evaluation
This study measures physical performance in adults being evaluated for a kidney transplant. It helps understand how fitness levels may affect transplant outcomes.
MartinAges 18 years+ - NCT07339189Recruiting
AI Suicide Prevention for Older Adults With HIV
This trial tests a smartphone-based AI program designed to help people with HIV who have had suicidal thoughts. It aims to reduce suicide risk by teaching coping skills through text-based conversations.
Newark, New JerseyAges 50 years+ - NCT06446453Recruiting
Lung Ultrasound-Guided Surfactant For Preterm Infants
This study tests whether giving surfactant medication guided by a lung ultrasound, instead of by X-ray, helps preterm babies with breathing problems get better without needing a breathing tube. Babies in the study receive surfactant through a thin tube while still on non-invasive breathing support.
Hartford, ConnecticutAges birth–2 hours - NCT07307066Recruiting
Ventilation feedback study for lung protection in ARDS
This study tests a computer system that gives real-time breathing machine advice to help protect the lungs of patients with severe lung injury (ARDS). It may help doctors adjust the ventilator settings to cause less damage.
Qujing, YunnanAges 18–75 - NCT03802695RecruitingPhase 1
Orca-Q pill to help during stem cell transplant
This Phase 1 trial studies Orca-Q to see if it is safe and works when added around the time of an allogeneic (donor) stem cell transplant for certain blood cancers. If you qualify, the study may offer a new option for managing the transplant immune response.
Duarte, CaliforniaAges 12–78 - NCT04356469RecruitingPhase 2
Donor stem cell transplant for serious blood disorders in children
This trial tests a special type of donor stem cell transplant (with donor T-cells removed) to treat serious non-cancer blood problems in children. It may help by resetting the bone marrow so the body can make healthy blood cells again.
St. Petersburg, FloridaAges birth–21 years - NCT06996119RecruitingPhase 1
Preventing graft-versus-host disease after stem cell transplant
This trial tests adding a drug called emapalumab to standard medications (cyclophosphamide, tacrolimus, mycophenolate mofetil) to prevent graft-versus-host disease in adults receiving a donor stem cell transplant. This approach aims to reduce complications after transplant.
Duarte, CaliforniaAges 18–75
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,196 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.