Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,201 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07268859Recruiting
Fan to prevent ticagrelor-related shortness of breath
This study tests whether using a small fan can help reduce the shortness of breath (dyspnea) that some people feel when they first start taking the blood thinner ticagrelor after a heart attack.
Istanbul, AvcılarAges 18–65 - NCT07269743Recruiting
Aerosol therapy for ARDS patients on ventilators
This trial tests whether delivering medication through a ventilator mask (aerosol therapy) can help adults with ARDS breathe better. It is designed for patients who are already on a breathing machine.
Lucknow, Uttar PradeshAges 18 years+ - NCT07269847Recruiting
Beef-heavy diet study for adults with pre-diabetes
This study tests whether a diet rich in beef can improve metabolic health in adults with pre-diabetes or metabolic syndrome compared to a typical healthy U.S. diet. Eligible participants will follow one of two meal plans for several weeks.
Guelph, Ontario - onAges 18–74 - NCT07270978RecruitingPhase 1
CD33-targeting cells for leukemia with leftover cancer cells
This trial tests a new treatment using special immune cells that target a protein called CD33 on leukemia cells. It's for people with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS) who still have small amounts of cancer cells left after other treatments.
Charlottesville, VirginiaAges 18 years+ - NCT07272187Recruiting
Heat therapy for small pancreatic and adrenal tumors
This trial tests a new treatment that uses an endoscope (a thin, flexible tube with a camera) to deliver heat energy directly to certain small tumors in the pancreas or adrenal gland. It may be an option for people who cannot have surgery or whose tumors are growing slowly.
Herlev, Capital RegionAges 18 years+ - NCT07273838RecruitingPhase 2
SGLT2 inhibitor for acute heart and kidney failure
This study tests whether a medicine called an SGLT2 inhibitor (which lowers blood sugar and helps the kidneys) can improve outcomes for people with acute heart failure and kidney problems. Participation involves taking the study drug or a placebo for a short time.
New Haven, ConnecticutAges 18–85 - NCT07276542RecruitingPhase 2/Phase 3
Ketamine for phantom limb pain: a six-month outpatient study
This study tests whether ketamine, given as an outpatient treatment, can reduce phantom limb pain over six months. You would come to a clinic for multiple ketamine sessions, with at least a week between each session, and be followed for a year.
Sacramento, CaliforniaAges 18–65 - NCT07278843Recruiting
Understanding vision loss in Usher syndrome type 1B
This study follows people with Usher syndrome type 1B over time to learn how vision loss progresses. It also tests new ways to measure functional vision, which may help design future treatments.
Paris, Île-de-France RegionAges 3–75 - NCT07281456RecruitingPhase 2
Testing a new oral drug for Sjögren's disease safety
This study tests the safety of a daily pill called Tofacitinib for adults with mild-to-moderate Sjögren's disease. It aims to see if this drug helps manage symptoms when other treatments haven't worked well.
Bethesda, MarylandAges 18–75 - NCT07283094RecruitingPhase 1
FHD-286 with decitabine and venetoclax for AML
This early-phase trial tests a new study drug called FHD-286 combined with two standard AML medicines (decitabine and venetoclax). It is for people with a high-risk type of AML that is either newly diagnosed (and you cannot have strong chemotherapy) or has come back after one prior treatment.
The Bronx, New YorkAges 18 years+ - NCT07283341Recruiting
Diet and Gut Movement in Irritable Bowel Syndrome
This study looks at how diet affects gut movement in children with irritable bowel syndrome (IBS). It may help find better ways to manage IBS symptoms.
Philadelphia, PennsylvaniaAges 8–18 - NCT07283809Recruiting
Heart care study for patients with common heart problems
This study is collecting information about people with common heart conditions to help doctors learn how to offer better care. If you have had a heart attack, heart failure, or atrial fibrillation, your experience can help improve treatment for others.
Montevarchi, AREZZOAges 18 years+ - NCT07284888Recruiting
Prone positioning for ARDS patients on ventilators
This study looks at how placing patients on their stomach (prone positioning) affects those with serious lung failure (ARDS) who are on a breathing machine. It aims to learn more about the best practices for this treatment in the ICU.
Nanjing, JiangsuAges 18 years+ - NCT07285044RecruitingPhase 2
Home cancer treatment program for Florida panhandle residents
This study tests whether people with certain cancers can safely receive their regular intravenous treatments at home instead of coming to the clinic. It aims to make treatment more convenient and improve satisfaction, especially for those living in the Florida Panhandle.
Jacksonville, FloridaAges 18 years+ - NCT07285915Recruiting
Stress and Cortisol in Cardiac Arrest
This study looks at how stress (specifically the hormone cortisol) affects people during a cardiac arrest. It may help doctors understand and improve care.
Pilsen, Czech RepublicAges 18–100 - NCT07289399Recruiting
Walking with diet for psoriasis and PCOS
This study tests whether adding treadmill walking to a diet plan helps women with psoriasis and PCOS who are obese. It compares the effects of diet alone versus diet plus walking on skin and hormone health.
Giza, DokkiAges 35–45 - NCT07290296Recruiting
Comparing muscle release and taping for knee pain
This trial compares two treatments for kneecap pain that has lasted at least 3 months: a muscle release technique and kinesio taping. The goal is to see which one helps reduce pain from daily activities like climbing stairs, running, or sitting for long periods.
CairoAges 18–30 - NCT07290712Recruiting
Intensive Care Recovery Study in the DACH Region
This study follows patients who spent more than 72 hours in the intensive care unit (ICU) to understand long-term effects and recovery. It may help improve care for future ICU patients.
Vienna, State of ViennaAges 18 years+ - NCT07290660Recruiting
Motor imagery and exercise for shoulder pain
This study tests whether combining mental movement training with targeted exercises can reduce shoulder pain caused by impingement syndrome. It aims to improve your shoulder function without surgery.
IstanbulAges 25–65 - NCT07293702Recruiting
IASTM therapy for shoulder pain from impingement
This study tests a hands-on therapy called IASTM (instrument-assisted soft tissue mobilization) to see if it can reduce pain, improve movement, and help your shoulder feel more stable. It is for people with subacromial impingement syndrome, a common cause of shoulder pain.
IstanbulAges 40–60 - NCT07294014Recruiting
Foot Arch Study in Women With Lipedema
This study looks at the arch of the foot and how the foot works in women with lipedema, a condition where fat builds up unevenly, usually in the legs. Participants will have their existing foot X-rays reviewed to compare foot structure between those with and without lipedema.
IstanbulAges 18–65 - NCT07296991Recruiting
Virtual reality exercise study for sedentary adults
This study tests if watching a virtual reality (VR) exercise video can give some of the same health benefits as real exercise. It might help people who are not active now and have slightly high blood sugar or blood pressure.
Detroit, MichiganAges 25–40 - NCT07297303Recruiting
Lung health study after stem cell transplant
This study follows lung health after a stem cell transplant from a donor, to understand and manage chronic graft-versus-host disease (a condition where donor cells attack the body). It may help people who are about to have their first donor transplant.
TaipeiAges 18 years+ - NCT07297576Recruiting
Sulforaphane to speed blood recovery after cord blood transplant
This trial tests if a natural compound called sulforaphane can help your blood cells recover faster after a cord blood transplant for high-risk blood cancers. If you qualify, you would receive this supplement along with your transplant.
TianjingAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,201 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.