Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,177 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07074158Enrolling by invitation
Looking for long COVID clues in blood
This study compares the blood of people with ongoing long COVID symptoms to healthy people, to look for differences in immune signals and gut bacteria. It could help find better ways to diagnose or treat long COVID.
Palo Alto, CaliforniaAges 18 years+ - NCT07072676Enrolling by invitation
Can a walker help prevent falls in neuromuscular disease?
This study tests if using assistive walking devices, after a short training period, can lower the risk of falls in people with neuromuscular diseases. It aims to help you stay steady and safe on your feet.
Bad FeilnbachAges 65–65 - NCT07053813Enrolling by invitation
Preventive genetic medicine trial for cancer risk
This trial tests whether a special program can help people with cancer-related genetic changes get the right screening and prevention care. It aims to improve how doctors manage your health based on your genes.
Denver, ColoradoAges 18–75 - NCT07053566Enrolling by invitation
Back muscle strengthening for rotator cuff tendinopathy
This study tests whether strengthening a back muscle (latissimus dorsi) helps people with rotator cuff tendinopathy. You may be able to join if you have had shoulder pain for at least 3 months and meet certain medical criteria.
AnkaraAges 18–50 - NCT06982456Enrolling by invitation
Manual therapy for neck pain in physiotherapy students
This study tests if manual therapy techniques help students with localized neck pain feel better. It focuses on pain in the upper shoulder muscle.
MurciaAges 18–40 - NCT06977555Enrolling by invitation
Talking with ICU patients on a breathing machine
This study looks at how nurses and doctors communicate with patients who are awake but on a breathing machine (ventilator) in the intensive care unit (ICU). The goal is to improve communication and make the experience better for patients.
OsloAges 18 years+ - NCT06970171Enrolling by invitation
Willingness to use a sleep apnea mouthpiece
This trial tests how well people accept a mouthpiece (mandibular advancement device) to treat obstructive sleep apnea (a condition where your breathing stops and starts during sleep). If you have sleep apnea and can wear a device that moves your lower jaw forward while you sleep, you may be able to join.
Greifswald, Mecklenburg-VorpommernAges 18–75 - NCT06938217Enrolling by invitation
Low-flow ECMO for adults with severe breathing failure
This study tests whether a gentler, low-blood-flow version of ECMO (a machine that helps oxygenate blood outside the body) is safe and effective for adults with very severe breathing failure. It is for patients who are already on a breathing machine and have very low oxygen levels despite that support.
San Antonio, TexasAges 18–65 - NCT06917794Enrolling by invitation
Genetic risk study for colon cancer patients
This study looks at how your genetic background and ancestry affect your risk for colon cancer. If you have been diagnosed with colon cancer and have a tumor sample available, you may be able to help researchers develop better risk scores.
Fortaleza, CearáAges 18 years+ - NCT06888570Enrolling by invitation
Liver health study for children & young adults with Down syndrome
This study looks at how eating patterns and body composition relate to fatty liver in children and young adults with Trisomy 21 (Down syndrome) or other genetic intellectual disabilities. It may help understand who is at risk and how to prevent liver problems.
Madrid, MadridAges 5–22 - NCT06879444Enrolling by invitation
Core strength and pelvic floor in Sjogren's
This study looks at how core stability and pelvic floor muscles work in people with primary Sjogren's syndrome. If you have this condition, the results may help doctors understand changes in muscle function.
Denizli, DenizliAges 18–65 - NCT06843096Enrolling by invitation
Special mammogram for finding breast cancer when origin is unknown
This trial uses a special mammogram with contrast dye to look for breast cancer in people who have cancer that started somewhere unknown (called Cancer of Unknown Primary). It may help find if the breast is the source, which could guide treatment.
RomeAges 18 years+ - NCT06837038Enrolling by invitation
Rhythmic beats to improve walking after stroke or Parkinson's
This trial tests whether listening to rhythmic music while walking can improve gait problems caused by stroke, Parkinson's disease, or other parkinsonism conditions. It is designed for people who can walk on their own but have an uneven or slow pace.
Beijing, Beijing MunicipalityAges 50–80 - NCT06830226Enrolling by invitation
Domperidone and preterm breast milk nutrients
This study looks at how domperidone, a medicine used to help increase breast milk supply, affects the nutritional content of breast milk from mothers of premature babies. By understanding this, doctors can better support your baby's growth.
LisbonAges Any age - NCT06826807Enrolling by invitation
Lifestyle change study for fatty liver disease
This study tests whether adding a liver stiffness measurement to a lifestyle program helps people with MASLD (a type of fatty liver disease) improve their liver health. It is designed for people who have fatty liver and at least one sign of metabolic syndrome, like high blood pressure or diabetes.
Bangkoknoi, BangkokAges 18–80 - NCT06807177Enrolling by invitation
Collagen injections for chronic neck pain
This trial tests if collagen injections into the neck can reduce chronic muscle pain and whether certain blood markers can show how well the treatment works. It may help if you have had neck pain for more than 12 weeks.
WarsawAges 18–65 - NCT06783998Enrolling by invitation
Breathing muscle health in sleep apnea
This trial studies how sleep apnea affects the muscles you use to breathe. It may help doctors better understand and treat breathing problems in people with sleep apnea.
Mersin, MersinAges 18 years+ - NCT06725199Enrolling by invitation
NMR metabolomic study in fibromyalgia
This study uses a special MRI-like test (NMR) to look at chemical changes in the body of people with fibromyalgia. It aims to better understand the condition and could help find new ways to diagnose or treat it.
Istanbul, IstanbulAges 18–65 - NCT06722443Enrolling by invitation
Probiotics and Prebiotics for Obesity
This trial tests whether adding probiotics and prebiotics to your diet can help with obesity and related health problems like prediabetes, diabetes, high cholesterol, or high blood pressure.
Granada, SpainAges 18–75 - NCT06710314Enrolling by invitation
Metabolic syndrome and recovery after colorectal cancer surgery
This trial studies how metabolic syndrome (a mix of high blood pressure, diabetes, and other factors) changes after colorectal cancer surgery. It aims to understand why some people's metabolic syndrome gets better after their tumor is removed, which could lead to better treatments.
Chongqing, Chongqing MunicipalityAges 18 years+ - NCT06708000Enrolling by invitationPhase 3
Personalized testing for new chest pain
This trial compares a personalized evaluation approach to standard care for people with new chest pain who might have heart disease. It aims to see if tailoring tests can improve diagnosis and outcomes.
HerningAges 30–75 - NCT06679972Enrolling by invitation
Impact of pregnancy liver condition on baby's breathing
This study looks at how a pregnancy liver condition (intrahepatic cholestasis) affects the baby's breathing after birth. It compares newborns whose mothers had this condition (and took medication for it) with newborns whose mothers did not have any liver issues during pregnancy.
Bucharest, BucharestAges 1 hour–4 weeks - NCT06657001Enrolling by invitation
Personalized nutrition study for gut health
This study uses information from your gut bacteria (microbiome) to create personalized nutrition advice. It is for people with gut conditions like IBD, IBS, or celiac disease, as well as healthy volunteers.
Rochester, MinnesotaAges 18 years+ - NCT06608407Enrolling by invitation
Platelet-rich plasma to prevent scar re-formation
This trial tests if a treatment called platelet-rich plasma (a concentration of your own blood cells) can help prevent scar tissue from coming back after surgery for Asherman's syndrome, a condition where scar tissue forms inside the uterus.
Beijing, Beijing MunicipalityAges 20–40
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,177 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.