Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,177 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT07567664Enrolling by invitation
Brain Changes in Neurodegenerative Diseases: A Tracking Study
This research study tracks how brain damage progresses in rare neurodegenerative diseases like frontotemporal dementia, primary progressive aphasia, PSP, CBS, and ALS. Researchers use brain imaging and tests to understand how these diseases spread in the brain, which could help develop better treatments.
Milan, LombardyAges 20–85 - NCT07563842Enrolling by invitation
Defining Abdominal Pressure Complications After Surgery
This study is updating medical definitions for a serious condition called abdominal compartment syndrome—where pressure builds up in the belly after surgery or critical illness. The research involves expert doctors and patients who have experienced this condition, working together to clarify what it is and how to recognize it.
LublinAges 18 years+ - NCT07551960Enrolling by invitation
Testing a Health Risk Prevention Platform for Adults
This study tests a digital platform called STELA that helps adults reduce their risk of heart disease and stroke by identifying and managing modifiable health factors like diet, exercise, and stress. You'll complete health assessments online to see if this preventive approach works.
Třinec, Moravian-Silesian RegionAges 18–80 - NCT07542158Enrolling by invitationPhase 2
Ultra-Low Radiation PET Imaging Study for Brain Scanning
This study tests a new way to take brain imaging scans (PET scans) using a very small amount of radioactive tracer. Researchers want to see if they can get clear pictures of your brain while reducing your radiation exposure compared to standard scans.
Englewood, New JerseyAges 18–120 - NCT07521371Enrolling by invitation
Intranasal Insulin for Autism in Children and Young Adults
This study observes how intranasal insulin (a form of insulin delivered through the nose) affects children and young adults with autism spectrum disorder who are already using or planning to use it as part of their regular care. Researchers will track changes in behavior and social skills over about 6 months.
Spring, TexasAges 4–21 - NCT07437924Enrolling by invitation
Bruxism and pelvic floor health in young women
This study looks at whether teeth grinding (bruxism) is linked to pelvic floor muscle function in young women. If you are 18–30 and either grind your teeth or do not, you may help researchers understand this connection.
KonyaAges 18–30 - NCT07424898Enrolling by invitation
Lactose Intolerance and Gut Health Study
This study looks at how lactose intolerance is linked to gut health. It is for adults with ongoing digestive issues like bloating, pain, or diarrhea, to see if their gut lining may be more sensitive.
IstanbulAges 18–70 - NCT07404384Enrolling by invitation
Slow breathing and resistance exercise for fibromyalgia
This study tests whether combining slow breathing exercises with light weightlifting (biceps curls) can help women with fibromyalgia feel better. It focuses on improving symptoms through a simple home-based routine.
Málaga, MálagaAges 18 years+ - NCT07331766Enrolling by invitation
Collaborative care for chronic pain patients
This trial tests a team-based treatment approach for people with chronic pain. You'll work with at least two pain clinic specialists to create a care plan that fits your needs.
Ottestad, InnlandetAges 18 years+ - NCT07320937Enrolling by invitation
Yiqi Fuyuan Paste formula for chronic fatigue syndrome
This trial tests whether a traditional Chinese medicine formula (Yiqi Fuyuan Paste) can help reduce fatigue in people with chronic fatigue syndrome. It is a double-blind, placebo-controlled study, meaning neither you nor the doctor will know which treatment you receive.
Shanghai, Pudong New AreaAges 18–65 - NCT07316075Enrolling by invitation
Heart and metabolic health in silent pheochromocytoma or paraganglioma
This study looks at heart and metabolic health in people who have pheochromocytomas or paragangliomas that do not produce extra hormones. It aims to understand whether these 'silent' tumors affect cardiovascular and metabolic health, and how they compare to other cases.
AthensAges 18 years+ - NCT07256795Enrolling by invitation
ME/CFS after COVID-19 vs. before the pandemic
This study looks at how the brain's protective barrier and immune system work in people with ME/CFS, comparing those who got sick before the COVID-19 pandemic to those who developed ME/CFS after a COVID-19 infection. It aims to understand why some people have lasting brain fog, fatigue, and other neuropsychiatric symptoms.
Baltimore, MarylandAges 18–70 - NCT07239167Enrolling by invitation
Weight change study for adults with obesity
This study looks at how weight changes affect health in adults with obesity. You may qualify if you have a high BMI and are willing to try a weight loss program.
Taipei, Zhongzheng DistAges 18 years+ - NCT07235345Enrolling by invitation
Lung medication with different oxygen levels for premature babies
This study tests a lung medication called pulmonary surfactant, given with different oxygen levels, to help very premature babies (born before 32 weeks) who have breathing difficulties. The goal is to see which oxygen level works best with non-invasive breathing support.
Henan, ZhengzhouAges 6 months–7 months - NCT07221565Enrolling by invitationPhase 1/Phase 2
Immune mapping trial for autoimmune conditions
This trial is testing a new way to map the immune system using electromagnetic signals and forecast how your body's immune system will respond. It may help people with autoimmune conditions like lupus or rheumatoid arthritis find new treatment options.
New York, New YorkAges Any age - NCT07209527Enrolling by invitationEarly Phase 1
Truway diagnostic tools in primary care
This trial tests new diagnostic tools that doctors can use in primary care. Researchers want to see if these tools help find the right diagnosis faster and more accurately.
New York, New YorkAges Any age - NCT07182175Enrolling by invitation
Heart health during adrenal tumor surgery study
This study looks at how different types of adrenal tumors might affect the heart during and after surgery. It aims to help doctors understand and reduce the risk of heart injury in patients having these tumors removed.
BeijingAges 18 years+ - NCT07176117Enrolling by invitation
Surfactant via airway device for breathing trouble in newborns
This trial tests if giving surfactant (a natural substance that helps lungs stay open) through a special airway device can help late preterm and early term infants with breathing problems. The goal is to see if this approach works better than current methods without needing a breathing tube.
Chula Vista, CaliforniaAges 8 months–9 months - NCT07171710Enrolling by invitation
Cyclosporine eye drops and tear duct plugs for dry eye in Sjögren's
This trial tests if using special eye drops (cyclosporine) along with tiny plugs placed in the tear ducts can improve dry eye symptoms in people with Sjögren's syndrome. The goal is to see if this combination works better than the drops alone.
Tianjin, Tianjin MunicipalityAges Any age - NCT07171424Enrolling by invitation
Understanding symptom questionnaires for overactive bladder
This study aims to better understand symptom questionnaires for women with overactive bladder (OAB). It will help doctors and patients know what changes in symptom scores mean for daily life.
IstanbulAges 18 years+ - NCT07169058Enrolling by invitation
Hands-on therapy for sleep apnea: a gentle technique
This study tests a gentle manual therapy applied to the neck to see if it can improve breathing and vital signs during sleep. It is for people with moderate to severe sleep apnea who are not currently using a CPAP machine or other breathing devices.
Mardin, MardinAges 18–65 - NCT07162285Enrolling by invitation
Bubble CPAP for Preterm Babies with Breathing Problems
This trial tests a special breathing support called bubble CPAP, given right after birth in the delivery room, to help preterm babies (born before 34 weeks) who are having trouble breathing. It aims to see if starting this treatment early can improve their breathing and health.
DhakaAges 5 minutes–30 minutes - NCT07112040Enrolling by invitation
Brief therapy for women after sexual violence
This trial tests a short therapy program for women who have experienced sexual violence in the past 6 months. The goal is to help reduce stress and trauma symptoms early on.
Madrid, Pozuelo de AlarcónAges 18 years+ - NCT07083713Enrolling by invitation
Group coaching for life goals with chronic conditions
This study tests if group coaching helps people with certain chronic conditions set and achieve life goals. You would join phone or video sessions with a coach and others like you.
Philadelphia, PennsylvaniaAges 18 years+
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,177 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.