Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,186 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06095440Recruiting
A study on treatment results for hepatorenal syndrome
This study looks back at medical records of people who had hepatorenal syndrome (a type of kidney failure linked to liver disease) while in the hospital. The goal is to understand what treatments were used and how well patients did, which might help guide future care.
Dallas, TexasAges 18–85 - NCT06096597RecruitingPhase 2/Phase 3
Amniotic Membrane Therapy for Bladder Pain
This trial tests a treatment made from amniotic membrane (a natural tissue) to help reduce pain and discomfort in people with Interstitial Cystitis (also called Painful Bladder Syndrome). It is for women who have tried at least one other treatment without success.
Clevleand, OhioAges 18 years+ - NCT06162546Recruiting
Registry for resistant nephrotic syndrome in children
This study tracks children with nephrotic syndrome whose kidney disease does not respond to usual treatments. It aims to collect information and samples to better understand resistant forms of the condition.
ViennaAges Up to 75 years - NCT06255678Recruiting
Angio-based check of heart artery treatment effect
This trial tests if special software can check the result of a balloon or stent procedure by looking at the X-ray movie of your heart arteries. It may help doctors decide if more treatment is needed.
WarsawAges 18 years+ - NCT06261918Recruiting
Breast cancer study: linking metabolism to tumor behavior
This study looks at how your metabolism (things like blood sugar and cholesterol) might be linked to tumor genes and growth in people with breast cancer. The goal is to find new ways to treat the disease based on your metabolic profile. You may be eligible if you have locally advanced breast cancer (Stage II–III) and are willing to share your medical records.
RomaAges 18 years+ - NCT06401538RecruitingPhase 2
BMB-101 for absence epilepsy and DEE
This trial tests a new drug called BMB-101 for people with absence epilepsy (including Jeavons syndrome) or developmental epileptic encephalopathies (DEE) like Dravet or Lennox-Gastaut. It aims to see if the drug can reduce seizure frequency and is safe.
Randwick, New South WalesAges 18–65 - NCT07523581RecruitingPhase 2
Exaluren for Alport Syndrome Kidney Disease
This study tests whether a new medication called exaluren can slow kidney damage in people with Alport Syndrome caused by specific genetic mutations. Alport Syndrome is a genetic condition that damages the kidneys, and this trial aims to see if exaluren can help preserve kidney function and reduce protein loss in urine.
Los Angeles, CaliforniaAges 12 years+ - NCT06337149Recruiting
Breathing and attention in children with Ondine syndrome
This study looks at how breathing affects attention in children with Ondine syndrome, also known as Congenital Central Hypoventilation Syndrome (CCHS). It aims to understand if children with this condition have changes in attention and how those relate to their breathing patterns, helping doctors plan better care.
ParisAges 6–16 - NCT06353620Recruiting
Brain connections study for certain epilepsies and genetic syndromes
This study uses MRI and a special EEG to understand brain connections in people with specific types of epilepsy or genetic conditions like Angelman syndrome and Dup15q. It may help find better ways to treat these conditions.
Conegliano, TrevisoAges 6–75 - NCT06373003Recruiting
Studying antiphospholipid syndrome without antibodies
This trial looks at people who have symptoms of antiphospholipid syndrome (APS) but test negative for the usual antibodies. It will compare these patients to those with positive antibody tests to better understand the condition and improve diagnosis and treatment.
Roma, RomeAges 18–65 - NCT06385353Recruiting
First leg clot size and long-term risk
This study looks at how the size and location of a first-time leg blood clot affects the risk of long-term problems like chronic pain or swelling. You may join if you have a new, symptomatic clot in one leg and haven't had one before.
Vichy, AllierAges 18 years+ - NCT06399640RecruitingPhase 1
Eltanexor and Venetoclax for relapsed MDS or AML
This trial tests two oral drugs, eltanexor and venetoclax, for people with MDS or AML that came back or did not get better after prior treatment. The goal is to see if this combination can help control the cancer.
Memphis, TennesseeAges 18 years+ - NCT06462430Recruiting
Registry for children with PTEN Hamartoma Tumor Syndrome
This study is creating a registry (a database) of children with PTEN Hamartoma Tumor Syndrome, a condition that can cause growths, large head size, and other health issues. By joining, you help doctors learn more about the condition and how to better care for kids like yours.
IstanbulAges 1 year+ - NCT06465953RecruitingPhase 3
Ivosidenib vs azacitidine for IDH1-mutated MDS
This trial tests if the drug ivosidenib alone or azacitidine alone can help people with a specific type of MDS that has an IDH1 mutation. It is for people who have not had strong MDS treatments yet.
Denver, ColoradoAges 18 years+ - NCT06544018Recruiting
Sleep and body clock study for CAPS patients and family members
This study looks at how CAPS (a genetic condition that causes inflammation) affects sleep and daily body rhythms. It compares people with CAPS to healthy family members living in the same home, to understand differences without any treatment being tested.
BronAges 6 years+ - NCT06551285Recruiting
Nutrition supplement for PCOS: effects on health and quality of life
This study tests whether a nutritional supplement can improve metabolism, reduce inflammation, and enhance quality of life in women with polycystic ovary syndrome (PCOS). It aims to help manage PCOS symptoms through dietary support.
Valencia, ValenciaAges 18–45 - NCT06554522RecruitingPhase 4
Testing CPAP for Premature Babies with Breathing Problems
This trial tests a breathing support method called CPAP for premature babies with breathing problems in Africa. It may help your baby get better oxygen and avoid more invasive treatments.
BanguiAges 1 hour–1 day - NCT06607991RecruitingPhase 1
Blinatumomab for children with steroid-resistant nephrotic syndrome
This trial tests a drug called blinatumomab for children with a kidney condition that doesn't respond to standard treatments. It aims to see if it can help when other drugs have failed or caused side effects.
Hangzhou, ZhejiangAges 2–17 - NCT06650943Recruiting
Nursing help for weight and metabolic health in early psychosis
This study tests a nursing program to help people with early psychosis manage weight and reduce the risk of metabolic syndrome (a cluster of conditions that raise heart disease risk). It's designed for people who have had their first psychotic episode within the last 5 years.
Bilbao, VizcayaAges Any age - NCT06681012Recruiting
Gelsectan for irritable bowel syndrome with diarrhea
This trial tests a supplement called Gelsectan to see if it reduces diarrhea and belly pain in people with diarrhea-predominant irritable bowel syndrome (IBS-D). It may help if you have loose, urgent stools more often than not.
LeuvenAges 18–65 - NCT06684782Recruiting
Restless leg syndrome in Thai Parkinson's patients
This trial is looking at how common restless leg syndrome is in people with Parkinson's disease in Thailand. It aims to better understand the link between the two conditions so doctors can improve care for people with both.
Bangkok, BangkokAges 18–80 - NCT06769373Recruiting
Whirlpool and contrast bath for CRPS after wrist fracture
This study tests whether warm water whirlpool baths or alternating hot and cold water baths (contrast bath) can help reduce pain and improve function in people with Complex Regional Pain Syndrome (CRPS) after a wrist fracture that was treated without surgery.
Afyonkarahisar, AfyonkarahisarAges 18–70 - NCT06783725Recruiting
Sleep help for people with Down syndrome
This study tests a sleep intervention to improve quality of life for people with Down syndrome who have trouble sleeping. A caregiver will help track sleep and take part in activities to improve sleep habits.
Birmingham, AlabamaAges 1–30 - NCT06825377Recruiting
Comparing high-protein vs. standard nutrition for ICU patients
This trial tests whether a high-protein diet or standard protein diet is better for critically ill patients who are at risk for refeeding syndrome (dangerous shifts in fluids and minerals when starting nutrition after starvation). The goal is to see which type of nutrition helps recovery.
TehranAges 18–65
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,186 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.