Clinical trials
Down Syndrome clinical trials
Below are recruiting down syndrome clinical trials, each written for real people, not researchers. We’re tracking 3,187 recruiting studies, each written for real people, not researchers, below.
Recruiting studies
- NCT06873841Recruiting
Cognitive therapy with or without biofeedback for tics in teens and young adults
This trial tests a talking therapy that helps manage tics by changing thoughts and feelings. Some people also get biofeedback, which uses sensors to help control body responses. Researchers want to see which approach works better for reducing tics in teens and young adults with Tourette's syndrome or bothersome tics.
Montreal, QuebecAges 14–21 - NCT06930417Recruiting
Williams syndrome and related 7q11.23 changes study
This study follows people with Williams syndrome, 7q11.23 duplication, or related genetic changes over time to understand how these conditions affect health and development. It also includes close family members to learn about the genetics.
Philadelphia, PennsylvaniaAges Any age - NCT06940908Recruiting
Living with Guillain-Barré syndrome as a child
This study interviews children who had Guillain-Barré syndrome (GBS) to understand their experiences after recovery. It may help doctors better support young patients with GBS.
Montpellier, OccitanieAges 10–18 - NCT06954103Recruiting
Stroke and heart health study for recent stroke patients
This study looks at how a moderate to severe stroke can affect your heart. It aims to understand the link between stroke and heart problems, which may help improve future care.
Wuhan, HubeiAges 18 years+ - NCT06955143Recruiting
Blood study for acute coronary syndrome patients
This study examines blood samples from people with different types of coronary artery disease to understand the condition better. It may help doctors learn how to treat heart problems in the future.
Lishui, ZhejiangAges 18 years+ - NCT06960369RecruitingPhase 1
Brain stimulation and probiotics for diarrhea-predominant IBS
This trial tests whether combining a type of brain stimulation (repetitive transcranial magnetic stimulation) with a probiotic tablet can help people with diarrhea-predominant irritable bowel syndrome. It aims to improve symptoms by targeting both the brain and the gut.
Suzhou, JiangsuAges 18–70 - NCT07000383Recruiting
Gelsectan for diarrhea-predominant IBS
This trial tests if Gelsectan, a dietary supplement, can safely reduce diarrhea and abdominal pain in people with diarrhea-predominant irritable bowel syndrome (IBS-D). It may be a new option for managing your symptoms.
Ho Chi Minh City, District 5Ages 18 years+ - NCT07043166Recruiting
Heart, kidney, and metabolic health study in Shanghai
This study looks at the link between heart, kidney, and metabolic health in adults living in Shanghai. It follows people who were part of an earlier health study to see how their health changes over time.
Shanghai, Shanghai MunicipalityAges 18 years+ - NCT07086599Recruiting
Sleep problems in psoriatic arthritis and SAPHO syndrome
This study looks at sleep problems in people with psoriatic arthritis or SAPHO syndrome. Participants will stay in the hospital for special sleep tests to understand their sleep issues better.
ParisAges 18 years+ - NCT07091175RecruitingPhase 2
Dupilumab for nephrotic syndrome in children
This trial tests if dupilumab can help children with nephrotic syndrome who still have relapses despite standard treatments. It aims to find a better way to control the disease and reduce steroid side effects.
Singapore, SingaporeAges 6–18 - NCT07102927Recruiting
Virtual reality training for stroke patients with neglect
This trial tests whether virtual reality exercises can help people with right-brain stroke overcome 'neglect' (trouble noticing things on their left side). It aims to improve daily function and quality of life.
SeoulAges 19–99 - NCT07146516Recruiting
Preventing retinal detachment in Stickler syndrome with laser
This study tests whether a preventative laser treatment can lower the risk of retinal detachment in people with Stickler syndrome. It's for those who have not yet had a retinal detachment and are healthy enough for the procedure.
Birmingham, AlabamaAges Any age - NCT07156318Recruiting
Drumming lessons for children with Down syndrome
This study tests whether drumming lessons can help children with Down syndrome. It may help with coordination, focus, or mood.
Nashville, TennesseeAges 7–15 - NCT07178925Recruiting
Long-term study of antiphospholipid syndrome
This trial follows patients with antiphospholipid syndrome over time to learn more about the condition. It may help researchers understand how the disease progresses and how to better manage it.
RouenAges 18–75 - NCT07284641RecruitingPhase 2
Stem cell transplant for immune disorders
This trial tests a stem cell transplant to treat common variable immunodeficiency (CVID) and other immune problems. It aims to replace a faulty immune system with a healthy one from a donor.
Pittsburgh, PennsylvaniaAges 5–40 - NCT07316127RecruitingPhase 2
Blood filtering for autoimmune long COVID
This trial tests if filtering certain antibodies from the blood can help people with long COVID who experience post-exertional malaise (PEM) and reduced function. It aims to see if this treatment reduces symptoms and improves daily life.
AmsterdamAges 18–65 - NCT07344714Recruiting
Predicting breathing help needs for newborns in NICUs
This study looks at newborns in a lower-level NICU to see which ones will need extra breathing support. The goal is to better predict which babies can be kept at their current hospital instead of being moved.
Rochester, MinnesotaAges 7 months–9 months - NCT07350018RecruitingPhase 4
Comparing Two Surfactants for Premature Babies With Breathing Problems
This trial compares two types of surfactant (Calfactant and Poractant Alfa) given through a less invasive method to very premature babies with breathing problems. It aims to see if one works better at helping them breathe without needing a breathing tube.
BursaAges birth–6 hours - NCT07378423Recruiting
Survey on signs of cancer at birth
This trial asks newly diagnosed children and young adults with certain types of cancer to fill out a questionnaire about signs of cancer present at birth. The answers may help improve early detection of childhood cancer.
BernAges Up to 21 years - NCT00556530Recruiting
Study genes and severity in 22q11.2 deletion
This study looks at how genetic differences affect how severe 22q11.2 deletion syndrome is for different people. It may help researchers understand what drives symptom severity and guide future care.
New York, New YorkAges Any age - NCT00697411Recruiting
Study of Aicardi syndrome in X-linked disorders
This trial looks at people with features that suggest Aicardi syndrome, a rare condition that can affect the brain and eyes and may include seizures. Researchers want to better understand the condition and how it shows up, which may help guide care in the future.
Houston, TexasAges Any age - NCT01601171Recruiting
Genetic study of reproductive problems and cleft lip or palate
This study looks at genetic (inherited) causes of certain hormone and reproductive conditions, including Kallmann syndrome and cleft lip/palate. You might be asked for medical and family history and possibly a DNA sample, helping researchers find what drives these conditions.
Lausanne, Canton of VaudAges Any age - NCT02050113Recruiting
Custom endograft repair for complex aortic aneurysms
This trial tests custom-made and doctor-modified grafts to treat complex bulges in the aorta (the body’s main artery) or the part going into the pelvis. It may help people who cannot use standard approved devices or who need treatment urgently because waiting is unsafe.
Worcester, MassachusettsAges 18 years+ - NCT02399527Recruiting
Lymphatic problem registry for tracking outcomes
This study enrolls people with certain lymphatic (lymph fluid) conditions to collect information and track how they do over time. It may help doctors better understand outcomes and improve care.
Boston, MassachusettsAges Any age
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Common questions
- Are there clinical trials for down syndrome?
- Yes. Clin2 currently lists 3,187 recruiting down syndrome studies from the U.S. registry, each rewritten for real people, not researchers, so you can see what it’s testing and who it’s for.
- How do I know if I qualify for a down syndrome trial?
- Each study lists its eligibility criteria — rules about age, diagnosis, and prior treatments. On every Clin2 trial page we explain these in words written for real people and offer a short, optional pre-screen for a fit read. The study team makes the final decision.
- Does it cost anything to join a down syndrome trial?
- Using Clin2 is always free. Many trials cover the cost of the study treatment and related visits; some reimburse travel. The study team explains exactly what’s covered before you decide.
Related conditions
Clin2 helps you find and understand clinical trials and does not provide medical advice. Study data comes from ClinicalTrials.gov. Talk with your doctor about whether a specific trial is right for you.